scholarly journals Early detection of kidney dysfunction in Egyptian patients with beta-thalassemia major

2017 ◽  
Vol 65 (3) ◽  
pp. 85-89 ◽  
Author(s):  
Osama ELsayed Bekhit ◽  
Hanaa H. El Dash ◽  
Marwa Salah Ahmed
Keyword(s):  
Early Detection ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Kidney Dysfunction ◽  
Beta Thalassemia Major ◽  
Egyptian Patients

GlutathioneS-transferase gene polymorphism: Relation to cardiac iron overload in Egyptian patients with Beta Thalassemia Major

Hematology ◽  
2015 ◽  
Vol 21 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Galila M. Mokhtar ◽  
Eman M. Sherif ◽  
Nevin M. Habeeb ◽  
Abeer A. Abdelmaksoud ◽  
Eman A. El-Ghoroury ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Iron Overload ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Cardiac Iron ◽  
Beta Thalassemia Major ◽  
Transferase Gene ◽  
Egyptian Patients ◽  
Cardiac Iron Overload

scholarly journals Electrocardiographic markers for the early detection of cardiac disease in patients with beta-thalassemia major

2010 ◽  
Vol 86 (2) ◽  
pp. 159-162 ◽  
Author(s):  
Kemal Nisli ◽  
Yavuz Taner ◽  
Oner Naci ◽  
Salcioglu Zafer ◽  
Karakas Zeynep ◽  
...  
Keyword(s):  
Early Detection ◽  
Cardiac Disease ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Beta Thalassemia Major ◽  
Electrocardiographic Markers

Study of Heart Diseases in Egyptian Patients with Beta Thalassemia Major

2014 ◽  
Vol 25 (4) ◽  
pp. 117-122
Author(s):  
Mona Hassan El Tagui ◽  
Mona Mohamed Hamdy ◽  
Mai Saad Eldin Mahmoud Badr
Keyword(s):  
Heart Diseases ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Beta Thalassemia Major ◽  
Egyptian Patients

scholarly journals Atrial fibrillation in beta thalassemia major: how to perform effective screening and early detection

Hematology ◽  
2017 ◽  
Vol 22 (6) ◽  
pp. 368-369 ◽  
Author(s):  
Vincenzo Russo ◽  
Andrea Antonio Papa ◽  
Anna Rago ◽  
Gerardo Nigro
Keyword(s):  
Atrial Fibrillation ◽  
Early Detection ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Effective Screening ◽  
Beta Thalassemia Major

scholarly journals Assessment of Subclinical Renal Glomerular and Tubular Dysfunction in Children with Beta Thalassemia Major

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 100
Author(s):  
Asmaa A. Mahmoud ◽  
Doaa M. Elian ◽  
Nahla MS. Abd El Hady ◽  
Heba M. Abdallah ◽  
Shimaa Abdelsattar ◽  
...  
Keyword(s):  
Cystatin C ◽  
Kidney Injury ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Good Survival ◽  
Control Group ◽  
Healthy Children ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Beta Thalassemia Major

Background: A good survival rate among patients with beta thalassemia major (beta-TM) has led to the appearance of an unrecognized renal disease. Therefore, we aimed to assess the role of serum cystatin-C as a promising marker for the detection of renal glomerular dysfunction and N-acetyl beta-D-glucosaminidase (NAG) and kidney injury molecule 1 (KIM-1) as potential markers for the detection of renal tubular injury in beta-TM children. Methods: This case-control study was implemented on 100 beta-TM children receiving regular blood transfusions and undergoing iron chelation therapy and 100 healthy children as a control group. Detailed histories of complete physical and clinical examinations were recorded. All subjected children underwent blood and urinary investigations. Results: There was a significant increase in serum cystatin-C (p < 0.001) and a significant decrease in eGFR in patients with beta-TM compared with controls (p = 0.01). There was a significant increase in urinary NAG, KIM-1, UNAG/Cr, and UKIM-1/Cr (p < 0.001) among thalassemic children, with a significant positive correlation between serum cystatin-C, NAG and KIM-1 as regards serum ferritin, creatinine, and urea among thalassemic patients. A negative correlation between serum cystatin-C and urinary markers with eGFR was noted. Conclusion: Serum cystatin-C is a good marker for detection of glomerular dysfunction. NAG and KIM-1 may have a predictive role in the detection of kidney injury in beta-TM children.

Beta-Thalassemia Major alters Sofosbuvir/Ledipasvir exposure in Hepatitis-C virus Infected Adolescent Patients

2021 ◽  
pp. 101747
Author(s):  
Iman A. El-Baraky ◽  
Maggie M. Abbassi ◽  
Fatma S. Ebied ◽  
Mohamed Hassany ◽  
Nirmeen A. Sabry ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Beta Thalassemia Major ◽  
Adolescent Patients
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