Erratum to ‘FOLFIRINOX or FOLFOXIRI in locally advanced duodenal adenocarcinoma: are we missing out?’

Appropriate surgical management of periampullary adenocarcinoma (ampullary adenocarcinoma, duodenal adenocarcinoma, distal cholangiocarcinoma, and pancreatic head adenocarcinoma) requires a familiarity with both anatomy and cancer biology. This review describes the clinical behavior of the various subtypes of periampullary adenocarcinoma, the appropriate diagnostic evaluation of the patient afflicted with these malignancies, the surgical anatomy of the pancreas and peripancreatic region, and the nature and outcome of contemporary therapeutic interventions. This review contains 9 figures, 7 tables, and 30 references. Key words: American Joint Committee on Cancer staging system, ampullary adenocarcinoma, borderline resectable, distal cholangiocarcinoma, duodenal adenocarcinoma, locally advanced, pancreatic adenocarcinoma, superior mesenteric artery first dissection

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Neoadjuvant chemotherapy in locally advanced duodenal adenocarcinoma

ecancermedicalscience ◽

10.3332/ecancer.2018.816 ◽

2018 ◽

Vol 12 ◽

Cited By ~ 4

Author(s):

Carlos Velandia ◽

Rafael Delgado Morales ◽

Carlos Coello ◽

Armando Gil Mendoza ◽

Gabriel Pérez ◽

...

Keyword(s):

Neoadjuvant Chemotherapy ◽

Locally Advanced ◽

Duodenal Adenocarcinoma

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FOLFIRINOX or FOLFOXIRI in locally advanced duodenal adenocarcinoma: are we missing out?

ESMO Open ◽

10.1136/esmoopen-2019-000633 ◽

2020 ◽

Vol 5 (5) ◽

pp. e000633

Author(s):

Angela Lamarca ◽

Lucy Foster ◽

Juan W Valle ◽

Thomas Satyadas ◽

Ajith Siriwardena

Keyword(s):

Locally Advanced ◽

Duodenal Adenocarcinoma

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Successful Extensive Multiorgan Resection of Malignant Duodenal Tumor: A Case Report

Acta Chirurgica Latviensis ◽

10.2478/chilat-2020-0009 ◽

2020 ◽

Vol 18 (1) ◽

pp. 36-38

Author(s):

Ilva Spiridonova ◽

Armands Sīviņš

Keyword(s):

Overall Survival ◽

Case Report ◽

Surgical Treatment ◽

Survival Rate ◽

Late Stage ◽

Locally Advanced ◽

Overall Survival Rate ◽

Duodenal Adenocarcinoma ◽

Gastrointestinal Malignancies ◽

Duodenal Tumor

SummaryDuodenal adenocarcinoma is one of the rarest tumours of all gastrointestinal malignancies. Due to rarity and late symptoms, duodenal cancers are diagnosed in late stage, but overall survival rate is high. We present a case of locally advanced duodenal adenocarcinoma with successful surgical treatment including multiorgan resection.

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A pathological complete response by chemotherapy with S-1 and oxaliplatin for a locally advanced duodenal adenocarcinoma in Lynch syndrome: a case report

Surgical Case Reports ◽

10.1186/s40792-019-0712-8 ◽

2019 ◽

Vol 5 (1) ◽

Author(s):

Satoshi Yasuda ◽

Suzuka Harada ◽

Akinori Tsujimoto ◽

Satoko Aoki ◽

Takeshi Takei ◽

...

Keyword(s):

Lynch Syndrome ◽

Abdominal Wall ◽

Pathological Complete Response ◽

Locally Advanced ◽

Complete Response ◽

Tnm Staging ◽

Upper Gastrointestinal Endoscopy ◽

Duodenal Adenocarcinoma ◽

Curative Intent ◽

Chemotherapeutic Regimen

Abstract Background Although primary duodenal adenocarcinoma (DA) is a rare malignancy representing ~ 0.5% of all gastrointestinal cancers, the incidence of DA is more frequent in Lynch syndrome. Because of its rarity, treatment strategies or optimal chemotherapeutic regimens have not been clearly defined for advanced DA. Case presentation A 72-year-old woman with Lynch syndrome visited our hospital with a right upper abdominal pain. Computed tomography (CT) showed wall thickness with enhancement in the second portion of the duodenum and adjacent abdominal wall, which suggested direct tumor invasion to the abdominal wall. Upper gastrointestinal endoscopy (UGE) showed a large ulcerative tumor in the second portion of the duodenum, and histological analysis revealed a poorly differentiated adenocarcinoma. A cT4N0M0, cStage IIB (Union for International Control Cancer TNM staging) DA was diagnosed. After three courses of chemotherapy with S-1 and oxaliplatin (SOX), follow-up CT and UGE showed shrinkage of the duodenal tumor. Therefore, the patient underwent pancreaticoduodenectomy with lymph node dissection with curative intent. Histological examination showed a pathological complete response to SOX therapy. The postoperative course was uneventful, and the patient was discharged on postoperative day 29. The patient received no adjuvant chemotherapy, and there has been no evidence of recurrence 6 months after the operation. Conclusions SOX therapy provided a remarkable response and can be an optimal chemotherapeutic regimen for advanced DA in Lynch syndrome.

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