TGIF, a homeodomain transcription factor, regulates retinal progenitor cell differentiation

2008 ◽  
Vol 87 (6) ◽  
pp. 571-579 ◽  
Author(s):  
Shinya Satoh ◽  
Sumiko Watanabe
Keyword(s):  
Transcription Factor ◽  
Cell Differentiation ◽  
Progenitor Cell ◽  
Retinal Progenitor Cell ◽  
Homeodomain Transcription Factor ◽  
Retinal Progenitor

scholarly journals Redox Signaling via Lipid Peroxidation Regulates Retinal Progenitor Cell Differentiation

2019 ◽  
Vol 50 (1) ◽  
pp. 73-89.e6 ◽  
Author(s):  
Shahad Albadri ◽  
Federica Naso ◽  
Marion Thauvin ◽  
Carole Gauron ◽  
Carola Parolin ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Cell Differentiation ◽  
Progenitor Cell ◽  
Redox Signaling ◽  
Retinal Progenitor Cell ◽  
Retinal Progenitor

scholarly journals A gene network downstream of transcription factor Math5 regulates retinal progenitor cell competence and ganglion cell fate

2005 ◽  
Vol 280 (2) ◽  
pp. 467-481 ◽  
Author(s):  
Xiuqian Mu ◽  
Xueyao Fu ◽  
Hongxia Sun ◽  
Phillip D. Beremand ◽  
Terry L. Thomas ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Ganglion Cell ◽  
Cell Fate ◽  
Gene Network ◽  
Progenitor Cell ◽  
Retinal Progenitor Cell ◽  
Retinal Progenitor ◽  
Cell Competence

scholarly journals Meis1 regulates Foxn4 expression during retinal progenitor cell differentiation

Biology Open ◽  
2013 ◽  
Vol 2 (11) ◽  
pp. 1125-1136 ◽  
Author(s):  
M. M. Islam ◽  
Y. Li ◽  
H. Luo ◽  
M. Xiang ◽  
L. Cai
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Retinal Progenitor Cell ◽  
Retinal Progenitor

scholarly journals A nutrient-sensitive restriction point is active during retinal progenitor cell differentiation

Development ◽  
2014 ◽  
Vol 141 (3) ◽  
pp. 697-706 ◽  
Author(s):  
N. K. Love ◽  
N. Keshavan ◽  
R. Lewis ◽  
W. A. Harris ◽  
M. Agathocleous
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Restriction Point ◽  
Retinal Progenitor Cell ◽  
Retinal Progenitor

scholarly journals The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Jerome Korzelius ◽  
Sina Azami ◽  
Tal Ronnen-Oron ◽  
Philipp Koch ◽  
Maik Baldauf ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Cell Differentiation ◽  
Cell Fate ◽  
Progenitor Cell ◽  
Lineage Commitment ◽  
Proneural Gene ◽  
Cell Lineages ◽  
Daughter Cells ◽  
Mechanistic Insight ◽  
Insight Into

Abstract In adult epithelial stem cell lineages, the precise differentiation of daughter cells is critical to maintain tissue homeostasis. Notch signaling controls the choice between absorptive and entero-endocrine cell differentiation in both the mammalian small intestine and the Drosophila midgut, yet how Notch promotes lineage restriction remains unclear. Here, we describe a role for the transcription factor Klumpfuss (Klu) in restricting the fate of enteroblasts (EBs) in the Drosophila intestine. Klu is induced in Notch-positive EBs and its activity restricts cell fate towards the enterocyte (EC) lineage. Transcriptomics and DamID profiling show that Klu suppresses enteroendocrine (EE) fate by repressing the action of the proneural gene Scute, which is essential for EE differentiation. Loss of Klu results in differentiation of EBs into EE cells. Our findings provide mechanistic insight into how lineage commitment in progenitor cell differentiation can be ensured downstream of initial specification cues.

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