Polar body genetic diagnosis (PbGD) is a useful tool to improve the results of assisted reproductive technology (ART) and helps couples in their reproductive decisions

2008 ◽  
Vol 90 ◽  
pp. S306-S307
Author(s):  
J.A. Crosby ◽  
C. Fabres ◽  
E. Fernandez ◽  
A. Mackenna ◽  
Y. Triantafilo ◽  
...  
Author(s):  
Bamgboye M Afolabi ◽  
Abayomi B Ajayi ◽  
Tola Ajayi ◽  
Victor D Ajayi ◽  
Ifeoluwa Oyetunji ◽  
...  

Introduction: COVID-19 pandemic has taken the world by storm and consequently, various reproductive medicine societies had since issued guidelines based on best judgement for the safety of IVF patients and attending health staffs Objective: The objective of this study was to assess the opinions of IVF staff in sub-Sahara Africa on the awareness of COVID-19 on Assisted Reproductive Technology. The study also evaluated some of the measures that can mitigate the effects of the virus in IVF clinics. Methodology: Different cadres of staff at Nordica Fertility Center (NFC) in Lagos, Nigeria were interviewed. Those interviewed included the Medical Director, Clinicians/Gynecologists, Clinic Manager, Nurses, Embryologists, Counsellor, Business Developing Unit, Client Liaison Officers and Accounts Officer. Their responses were collated, and the key points were documented. Each staff in face mask was visited by one interviewer who observed all government-recommended sanitary precautions including wearing a facemask and maintaining social distance between her and the interviewee. Result: The response of the MD on the fate of IVF clinic in Africa within the next 6 months to 1 year of the Covid-19 pandemic was that the overall economy is a major determinant of the ability of clients to pay for IVF services. Infertile women would still want to have children but “how would they pay for the services?” since ART is not subsidized by the government but mostly paid as out-of-pocket expense in this part of the world. The main points were that IVF clinics are not immune to the economy and vaccine may or may not favor IVF, reasons being; The virus is about 5 months old hence still much to be discovered There is no solid evidence that the virus affects reproduction No evidence of mother-to-child transmission and The virus can survive in cold environment therefore, it could survive cryopreservation. The embryologist was of the opinion that IVF clinics in Africa need to understand the virus more to decide whether: Attend to COVID-19 patients or not and if so, how best to care for them Better prepare modalities of cryopreservation such as Appropriate equipment Batching gametes together with HIV or Hepatitis patients In same or separate equipment and Getting special cryo-tanks for Covid-19 patients. Embryologist agreed that clinics will be able to perform other adjunct fertility treatment such as Pre-implantation Genetic Diagnosis (PGD), dependent on clinics’ ability to have separate equipment for Covid19-positive and negative patients. Conclusion: Africa is not left behind in experiencing the effects of COVID-19 and ART, for which concerns for the survival of privately owned clinics to ensure and safeguard the health and safety of patients, staff and the unborn babies are expressed. As of now, no-one is sure of patients that are symptomatic and those not symptomatic, as testing in the country, just like in most parts of the world, are still inadequate. When a vaccine is available, it may be mandatory for every IVF patient to get a shot. The main points of other cadres of staff are discussed.


2012 ◽  
Vol 61 (3) ◽  
pp. 75-82
Author(s):  
Julija Artemevna Loginova ◽  
Olga Gavrilovna Chiryaeva

Preimplantation genetic diagnosis was first reported 20 years ago. During this time the range of possibilities of assisted reproductive technology has expanded and the possibility of molecular diagnosis of single cells greatly increased. Preimplantation diagnosis has evolved from an experimental procedure to an efficient form of Prenatal Diagnosis, which broadened the indications for Prenatal Diagnosis and can be applied at the earliest stage. This review shows the current state of preimplantation genetic diagnosis and describes its capabilities


2003 ◽  
Vol 80 (2) ◽  
pp. 467-468 ◽  
Author(s):  
Lawrence Werlin ◽  
Ingrid Rodi ◽  
Alan DeCherney ◽  
Ellen Marello ◽  
David Hill ◽  
...  

Author(s):  
Amber Mathiesen ◽  
Kali Roy

For those with an increased risk of having a child with a genetic condition, reproductive options include avoiding pregnancy altogether, undertaking prenatal diagnosis in a current pregnancy, and preventing the transmission of the genetic changes responsible for the condition to a child. This chapter on assisted reproductive technology and reproductive options for the at-risk couple describes the basic techniques of assisted reproductive technologies as well as reproductive testing options prior to in vitro fertilization, including preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD). It includes a brief overview of ovarian stimulation, intrauterine insemination (IUI), and in vitro fertilization. This chapter discusses the details of PGS including the process and its limitations. It also includes a discussion of PGD, including the process, such as linkage analysis, and limitations, such as allele dropout.


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