Stress does not appear to negatively affect testicular function in infertile men

2020 ◽  
Vol 113 (4) ◽  
pp. 771
Author(s):  
R. Matthew Coward
1990 ◽  
Vol 127 (3) ◽  
pp. 523-532 ◽  
Author(s):  
F. Jockenhövel ◽  
S. A. Khan ◽  
E. Nieschlag

ABSTRACT Serum FSH levels in fertile and infertile men were determined by applying the Sertoli cell in-vitro bioassay and six different immunoassays. Bioassay and immunoassay estimates were significantly correlated (r ranging from 0·78 to 0·86; P<0·01). On average, all immunoassays measured lower FSH concentrations in samples with low FSH levels and higher FSH concentrations in those with high FSH levels compared with the bioassay. Ratios of bioactivity to immunoreactivity (B/I) were highest in fertile men and lowest in men with severe disturbances of testicular function. Depending on which immunoassay was used these differences were either significant or only marginal. Dose–response characteristics for WHO FSH standard preparation 78/549, used in the bioassay as well as in the immunoassays, were different between immunoassays and the bioassay, suggesting that decreasing B/I ratios with increasing FSH serum levels were method-related and reflected different slopes of the dose–response characteristics of the assays, rather than being true changes in the molecular composition of FSH. The present investigation underlines the necessity of choosing the immunoassay used for comparison with the bioassay carefully and of validating the system in regard to parallelism between dose–response characteristics. B/I ratios must be interpreted with great caution and previous studies which report changing B/I ratios in various endocrine situations may have to be reevaluated. Journal of Endocrinology (1990) 127, 523–532


Andrologia ◽  
2012 ◽  
Vol 45 (6) ◽  
pp. 379-385 ◽  
Author(s):  
M. C. Lardone ◽  
A. Piottante ◽  
R. Valdevenito ◽  
M. Ebensperger ◽  
A. Castro

2005 ◽  
Vol 173 (4S) ◽  
pp. 368-368
Author(s):  
Shai Shefi ◽  
Phiroz Tarapore ◽  
Paul J. Turek
Keyword(s):  

2004 ◽  
Vol 171 (4S) ◽  
pp. 415-415
Author(s):  
Deborah M. Spaine ◽  
Renato Fraietta ◽  
Carolina Homsi ◽  
Agnaldo P. Cedenho ◽  
Miguel Srougi

2004 ◽  
Vol 171 (4S) ◽  
pp. 365-365
Author(s):  
Tamer M. Said ◽  
Shyam Allamaneni ◽  
Kiran P. Nallella ◽  
Rakesh K. Sharma ◽  
Mohamed A. Bedaiwy ◽  
...  
Keyword(s):  

10.32947/357 ◽  
2018 ◽  
Vol 18 (1) ◽  
pp. 1-10

Thirty three infertile women were divided into two groups according to their BMI (21 obese and 12 overweight) there age ranges between (16-41) years, with their husbands twenty one infertile men and twelve fertile men and their ages range between (23-46) years. In the present study we observed that several indicators affect the fertility such as BMI in infertile obese women which was 34.65 kg/m2. That is higher than that of overweight infertile women that recorded 24.87 kg/m2. obese housewives scored the highest percentage (85.71%) compared with the overweight group (25%), In addition the obese age group between 30-41 years scored (66.67%) compared with the overweight group whose members’ age 16-29.9 years scored 75%. However, drinking cola (soft drink) percentage in obese infertile women was (85.71%) and the tea consumption was higher in overweight group (66.67%). The hormones FSH and LH decrease in obese women but serum prolactin hormone increased twice about 29.27 ng/ml in comparison with overweight group. Testosterone hormone decreased in obese women but Leptin in obese women (19.52 μg/L) was higher than that of overweight women (11.03 μg/L). Infertile unemployed men got the highest percentage of 66.67%. Besides, the smoker infertile men were higher in percentage (80.95%) compared with fertile men 41.67%. The elevated LH, FSH and prolactin values are significantly high (p<0.01) (7.895 mlU/ml, 9.89 mlU/ml and 13.33 ng/ml) respectively, but the testosterone was significantly low (3.91 ng/dl) in comparison with fertile men(21.76ng/dl). Whileleptin significantly increased in infertile men more than the fertile ones. These changes in hormones have a great correlation with semen characteristics as the abnormalities in sperms increased to (64.52) and the percentage of rapid, progressive and non -progressive motility decreased, but the immotile motility was highly significant (65.71) in infertile men. As a result this indicates that the reason of infertility is shared between the wife and husband.


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