Steroidal glycoalkaloids from Solanum lyratum inhibit the pro-angiogenic activity of A549-derived exosomes

Fitoterapia ◽  
2020 ◽  
Vol 141 ◽  
pp. 104481
Author(s):  
Xiao Du ◽  
Jian-Nong Wang ◽  
Jian Sun ◽  
Tong Wu ◽  
Xiao-Qiang Cao ◽  
...  
Keyword(s):  
Angiogenic Activity ◽  
Solanum Lyratum

Highly Potent rhenium(I) Tricarbonyl Complexes with Dual Anticancer and Anti-Angiogenic Activity Against Colorectal Carcinoma

2020 ◽  
Author(s):  
Joachim Delasoie ◽  
Aleksandar Pavic ◽  
Noémie Voutier ◽  
Sandra Vojnovic ◽  
Aurélien Crochet ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Anticancer Drugs ◽  
Xenograft Model ◽  
Therapeutic Window ◽  
Low Doses ◽  
Sunitinib Malate ◽  
Angiogenic Activity ◽  
Antimetastatic Activity ◽  
Clinical Drugs

Synthesized and characterized a series of rhenium(I) trycarbonyl-based complexes with increased lipophilicity. Two of these novel compounds were discovered to possess remarkable anticancer, anti-angiogenic and antimetastatic activity <i>in vivo</i> (zebrafish-human CRC xenograft model), being effective at very low doses (1-3 µM). At doses as high as 250 µM the complexes did not provoke toxicity issues encountered in clinical anticancer drugs (cardio-, hepato-, and myelotoxicity). The two compounds exceed the antiproliferative and anti-angiogenic potency of clinical drugs cisplatin and sunitinib-malate, and display a large therapeutic window.

Crocin Rich Extract of Nyctanthes arbor-tristis Flower Calyx Induces Anti-angiogenic Activity

2015 ◽  
Vol 06 (999) ◽  
pp. 1-1
Author(s):  
Neha D.Pawar ◽  
Shital S.Panchal ◽  
Kumaravelu J. ◽  
Tasneem Shahmalak ◽  
Chhaya Gadgoli
Keyword(s):  
Angiogenic Activity

scholarly journals Vinegar-processed Curcuma phaeocaulis promotes anti-angiogenic activity and reduces toxicity in zebrafish and rat models

2021 ◽  
Vol 59 (1) ◽  
pp. 410-417
Author(s):  
Wan Liao ◽  
Yi Chen ◽  
Zongping Zhu ◽  
Jiao Chen ◽  
Tianhui Gao ◽  
...  
Keyword(s):  
Angiogenic Activity ◽  
Rat Models

Impact of alginate concentration on the viability, cryostorage, and angiogenic activity of encapsulated fibroblasts

2016 ◽  
Vol 65 ◽  
pp. 269-277 ◽  
Author(s):  
Swetaparna Mohanty ◽  
Yang Wu ◽  
Nilay Chakraborty ◽  
Pravansu Mohanty ◽  
Gargi Ghosh
Keyword(s):  
Angiogenic Activity ◽  
Alginate Concentration

Functionalization of Ultrabithorax Materials with Vascular Endothelial Growth Factor Enhances Angiogenic Activity

2016 ◽  
Vol 17 (11) ◽  
pp. 3558-3569 ◽  
Author(s):  
David W. Howell ◽  
Camille L. Duran ◽  
Shang-Pu Tsai ◽  
Sarah E. Bondos ◽  
Kayla J. Bayless
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Vascular Endothelial ◽  
Angiogenic Activity ◽  
Endothelial Growth Factor
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