Potential role of lycopene in targeting proprotein convertase subtilisin/kexin type-9 to combat hypercholesterolemia

2017 ◽  
Vol 108 ◽  
pp. 394-403 ◽  
Author(s):  
Sahir Sultan Alvi ◽  
Irfan A. Ansari ◽  
Imran Khan ◽  
Johar Iqbal ◽  
M. Salman Khan
Keyword(s):  
Potential Role ◽  
Proprotein Convertase

scholarly journals Potential Role of Proprotein Convertase SKI-1 in the Mineralization of Primary Bone

2008 ◽  
Vol 189 (1-4) ◽  
pp. 25-32 ◽  
Author(s):  
Jeff P. Gorski ◽  
Nichole T. Huffman ◽  
Chaoying Cui ◽  
Ellen P. Henderson ◽  
Ronald J. Midura ◽  
...  
Keyword(s):  
Potential Role ◽  
Proprotein Convertase ◽  
Primary Bone

POPDC proteins and cardiac function

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand
Keyword(s):  
Potential Role ◽  
Striated Muscle ◽  
Short Review ◽  
Effector Proteins ◽  
Muscle Disease ◽  
Disease Genes ◽  
Protein Protein Interaction ◽  
Interaction Partners ◽  
And Function

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.

1255: Potential Role of Postoperative Azotemia in Predicting Response to Interleukin-2 (IL-2) Immunotherapy Following Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 414-414
Author(s):  
John S. Lam ◽  
Rakhee H. Gael ◽  
Tobias Klatte ◽  
Fairooz F. Kabbinavar ◽  
Arie S. Belldegrun ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Potential Role ◽  
Interleukin 2 ◽  
Cytoreductive Nephrectomy

The Effect of Path Length and Display Size on Memory for Spatial Information

2012 ◽  
Vol 59 (3) ◽  
pp. 147-152 ◽  
Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay
Keyword(s):  
Path Length ◽  
Potential Role ◽  
Spatial Information ◽  
Recall Performance ◽  
Minor Role ◽  
Length Effect ◽  
Serial Memory ◽  
Fixed Reference ◽  
A Minor

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.

The Potential Role of the Cytochrome P-450 2D6 Pharmacogenetic Polymorphism in Drug Abuse

1997 ◽  
Author(s):  
Edward M. Sellers ◽  
S. Victoria Otton ◽  
Rachel F. Tyndale
Keyword(s):  
Drug Abuse ◽  
Potential Role ◽  
Cytochrome P 450

Potential Role of Sex-Steroid Depletion in Dementia: Implications for Treatment

2009 ◽  
Author(s):  
Channing Harris
Keyword(s):  
Potential Role ◽  
Sex Steroid

Evaluating the potential role of phosphatidylethanol as sensitive and specific biomarker for monitoring sobriety in liver transplant candidates

2017 ◽  
Author(s):  
F Braun ◽  
A Bernsmeier ◽  
W Weinmann ◽  
M Yegles ◽  
T Becker ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Potential Role ◽  
Transplant Candidates

Business Model Literature Overview

2014 ◽  
pp. 79-130 ◽  
Author(s):  
Ales Novak
Keyword(s):  
Business Model ◽  
Financial Reporting ◽  
Business Models ◽  
Potential Role ◽  
Financial Instruments ◽  
Business Logic ◽  
Literature Overview ◽  
Ifrs 9 ◽  
Definition Of

The term ?business model' has recently attracted increased attention in the context of financial reporting and was formally introduced into the IFRS literature when IFRS 9 Financial Instruments was published in November 2009. However, IFRS 9 did not fully define the term ‘business model'. Furthermore, the literature on business models is quite diverse. It has been conducted in largely isolated fashion; therefore, no generally accepted definition of ?business model' has emerged. Therefore, a better understanding of the notion itself should be developed before further investigating its potential role within financial reporting. The aim of this paper is to highlight some of the perceived key themes and to identify other bases for grouping/organizing the literature based on business models. The contributions this paper makes to the literature are twofold: first, it complements previous review papers on business models; second, it contains a clear position on the distinction between the notions of the business model and strategy, which many authors identify as a key element in better explaining and communicating the notion of the business model. In this author's opinion, the term ‘strategy' is a dynamic and forward-looking notion, a sort of directional roadmap for future courses of action, whereas, ‘business model' is a more static notion, reflecting the conceptualisation of the company's underlying core business logic. The conclusion contains the author's thoughts on the role of the business model in financial reporting.

Potential role of vitamin D in restoring sensitivity to mTOR inhibitors in hepatocellular carcinoma (HCC): 1,25(OH)vitamin D (VitD) reverts everolimus (EVE) resistance in a hcc cell line

2017 ◽  
Author(s):  
Claudia Pivonello ◽  
Donatella Paola Provvisiero ◽  
Mariarosaria Negri ◽  
Gilda Di Gennaro ◽  
Angelis Cristina de ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Vitamin D ◽  
Cell Line ◽  
Potential Role ◽  
Mtor Inhibitors
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