Glutaredoxin-1 promotes pregnancy-induced vascular complications by altering placental angiogenesis

Background: Haemostatic puncture closure devices for rapid and effective hemostasis after arterial catheterisation are a comfortable alternative to manual compression. Implanting a collagen plug against the vessel wall may become responsible for other kind of vascular injuries i.e. thrombotic or stenotic lesions and peripheral embolisation. The aim of this paper is to report our clinically relevant vascular complications after Angio-Seal® and to discuss the results in the light of the current literature. Patients and methods: We report the symptomatic vascular complications in 17 of 7376 patients undergoing diagnostic or therapeutic catheterisation between May 2000 and March 2003 at the University Hospital Basel. Results: Most patients presented with ischaemic symptoms, arterial stenoses or occlusions and thrombotic lesions (n = 14), whereas pseudoaneurysms were extremely rare (n = 3). Most patients with ischaemic lesions underwent vascular surgery and all patients with a pseudoaneurysm were successfully treated by ultrasound-guided compression. Conclusions: Severe vascular complications after Angio-Seal® are rare, consistent with the current literature. There may be a shift from pseudoaneurysms to ischaemic lesions.

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Paraoxonase-1 and myeloperoxidase correlate with vascular biomarkers in overweight patients with newly diagnosed untreated hyperlipidaemia

VASA ◽

10.1024/0301-1526/a000643 ◽

2017 ◽

Vol 46 (5) ◽

pp. 370-376 ◽

Cited By ~ 2

Author(s):

Anita Szentpéteri ◽

Noémi Zsíros ◽

Viktória E. Varga ◽

Hajnalka Lőrincz ◽

Mónika Katkó ◽

...

Keyword(s):

Adhesion Molecule ◽

Oxidized Ldl ◽

Vascular Complications ◽

Cd40 Ligand ◽

Paraoxonase 1 ◽

Intercellular Adhesion Molecule ◽

Pon1 Activity ◽

Intercellular Adhesion Molecule 1 ◽

Inflammatory Parameters ◽

Vascular Biomarkers

Abstract. Background: In hyperlipidaemic state, increased levels of myeloperoxidase (MPO) and decreased paraoxonase-1 (PON1) activity have been reported; however, their relationships with other atherosclerotic biomarkers have not been completely clarified. Patients and methods: Serum concentrations of lipid and inflammatory parameters, MPO levels, and PON1 activities were investigated in 167 untreated hyperlipidaemic patients with and without vascular complications and in 32 healthy controls. Additionally, levels of CD40 ligand (sCD40L) and asymmetric dimethyl arginine (ADMA), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1, and oxidized LDL were determined. Results: We found elevated C-reactive protein (CRP), ADMA, sCD40L, sICAM-1 concentrations, and higher MPO levels in patients with vascular complications compared to those without. The PON1 arylesterase activity correlated negatively with sCD40L, ADMA, and sICAM-1 levels, respectively. In contrast, MPO concentrations showed positive correlations with sCD40L, ADMA, and sICAM-1 levels, respectively. Conclusions: It can therefore be stated that PON1 activity and MPO level correlate strongly with the vascular biomarkers, highlighting the importance of the HDL-associated pro- and antioxidant enzymes in the development of endothelial dysfunction and atherogenesis.

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Use of vascular closure devices for endovascular interventions requiring a direct puncture of PETE grafts

VASA ◽

10.1024/0301-1526/a000677 ◽

2018 ◽

Vol 47 (2) ◽

pp. 119-124 ◽

Cited By ~ 2

Author(s):

Artur I. Milnerowicz ◽

Aleksandra A. Milnerowicz ◽

Marcin Protasiewicz ◽

Wiktor Kuliczkowski

Keyword(s):

Statistical Significance ◽

Vascular Complications ◽

Vascular Complication ◽

Inguinal Region ◽

Closure Device ◽

Manual Compression ◽

Direct Puncture ◽

Endovascular Interventions ◽

Vascular Closure Devices ◽

Closure Group

Abstract. Background: Effectiveness of vascular closure devices during endovascular procedures requiring a direct puncture of a vascular prosthesis placed in the inguinal region is unknown. Patients and methods: The retrospective analysis included 134 patients with a history of polyethylene terephthalate (PETE) graft implantation in the inguinal region. In 20 (15 %) patients, haemostasis was achieved with manual compression, in 21 (16 %) with the StarClose™, and in 93 (69 %) with the AngioSeal™ device. Results: The incidence of vascular complications in the manual compression group was higher (at a threshold of statistical significance) than in the device closure group (45.0 vs. 24.5 %, p = 0.059). The difference was considered statistically significant when manual compression was compared with the AngioSeal™ closure group (45.0 vs. 13.9 %, p < 0.01). The vascular complication rate in the StarClose™ group was significantly higher than in the AngioSeal™ group (71.4 vs. 13.9 %, p < 0.000001). While haematomas were the only vascular complications observed after application of AngioSeal™, both haematomas and pseudoaneurysms were found in the StarClose™ group. Conclusions: The AngioSeal™ vascular closure device provides better local haemostasis than the StarClose™ device or manual compression during endovascular interventions requiring a direct puncture of PETE grafts

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Transradial Approach for ad hoc Coronary Interventions: Procedural Results and Vascular Complications

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(97)83787-4 ◽

1998 ◽

Vol 31 (2) ◽

pp. 17A-18A ◽

Cited By ~ 1

Author(s):

G Barbeau

Keyword(s):

Ad Hoc ◽

Vascular Complications ◽

Transradial Approach ◽

Coronary Interventions

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Platelet Behaviour in Non-Insulin-Dependent Diabetes -Influence of Vascular Complications, Treatment and Metabolic Control

Thrombosis and Haemostasis ◽

10.1055/s-0038-1661564 ◽

1986 ◽

Vol 55 (03) ◽

pp. 361-365 ◽

Cited By ~ 8

Author(s):

I Peacock ◽

M Hawkins ◽

S Heptinstall

Keyword(s):

Blood Glucose ◽

Metabolic Control ◽

Platelet Reactivity ◽

Platelet Rich Plasma ◽

Vascular Complications ◽

Adenosine Diphosphate ◽

Glycosylated Haemoglobin ◽

Insulin Dependent Diabetes ◽

Lipid Levels ◽

Insulin Dependent

SummaryPlatelet-rich plasma was prepared from 47 patients with noninsulin-dependent diabetes treated with glibenclamide and metformin, and 21 controls. The release of radio-labelled 5-hydroxy-tryptamine in response to aggregating agents (adenosine diphosphate, adrenaline and sodium arachidonate), and the effects on release of a selective thromboxane inhibitor (UK-34787) were investigated. Subsequently, 20 of the diabetic subjects were chosen at random for treatment with insulin; the remainder continued to take tablets. Platelet studies were then repeated, in all patients, after 4 and 6 months.The results showed an association between platelet behaviour and the presence of vascular complications, and were consistent with previous observations of reduced platelet reactivity in patients taking sulphonylureas. There was no correlation of platelet reactivity with blood glucose, glycosylated haemoglobin or lipid levels.

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VASCULAR COMPLICATIONS OF CHRONIC PANCREATITIS AND ROLE OF EUS IN MANAGEMENT: EXPERIENCE FROM TERTIARY CARE CENTER IN NORTHWESTERN INDIA

10.1055/s-0040-1704545 ◽

2020 ◽

Author(s):

V Goel ◽

A Jhajharia ◽

V Chauhan ◽

M Ameta ◽

V Agarwal

Keyword(s):

Chronic Pancreatitis ◽

Care Center ◽

Tertiary Care ◽

Vascular Complications ◽

Tertiary Care Center ◽

Northwestern India ◽

Management Experience

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Vascular Complications after Peripheral (V-A) ECLS Cannulation in Cardiogenic Shock

10.1055/s-0040-1705366 ◽

2020 ◽

Author(s):

C. Ilias ◽

N. Pizanis ◽

A. Koch ◽

M. Papathanasiou ◽

P. Luedike ◽

...

Keyword(s):

Cardiogenic Shock ◽

Vascular Complications

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Downsizing – the Future of Interventional Cardiology

Interventional Cardiology Review ◽

10.15420/icr.2012.7.1.28 ◽

2012 ◽

Vol 7 (1) ◽

pp. 28

Author(s):

Giovanni Amoroso ◽

Keyword(s):

Contrast Agent ◽

Vascular Complications ◽

Cost Savings ◽

Length Of Hospital Stay ◽

Interventional Cardiology ◽

Coronary Intervention ◽

Transradial Approach ◽

Technical Developments ◽

Coronary Procedures ◽

Angiographic Image

The concept of downsized catheters (i.e., using catheters smaller than 6 French) for invasive coronary procedures, such as diagnostic cardiac catheterisation and percutaneous coronary intervention, has been developing over the years, particularly as a result of the rise of the transradial approach. Recent advances have allowed the use of smaller and sheathless catheters, which confer a number of advantages – such as fewer vascular complications, reduced use of contrast agent and reduced haemostasis – thus increasing patient safety and comfort and allowing more rapid patient mobilisation. Reductions in patient complications, number and length of hospital stay, and amount of contrast agent used can also lead to cost savings. While the use of smaller catheters has been hindered in the past because of poor angiographic image quality, new automated contrast injectors have helped overcome this limitation. There is a need to make interventional cardiologists worldwide more aware of the benefits of downsizing, in the light of the latest technical developments and the increased use of transradial approach.

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Management and Prevention of Vascular Complications Related to Transcatheter Aortic Valve Implantation and Aortic Aneurysm Repair Procedures – A Technical Note

Interventional Cardiology Review ◽

10.15420/icr.2010.5.1.81 ◽

2010 ◽

Vol 5 (1) ◽

pp. 81

Author(s):

Andrea Pacchioni ◽

Dimitris Nikas ◽

Carlo Penzo ◽

Salvatore Saccà ◽

Luca Favero ◽

...

Keyword(s):

Aortic Valve ◽

Aortic Aneurysm ◽

Transcatheter Aortic Valve Implantation ◽

Severe Aortic Stenosis ◽

Vascular Complications ◽

Technical Note ◽

Closure Device ◽

Transcatheter Aortic Valve ◽

Aortic Valve Implantation ◽

Valve Implantation

Transcatheter aortic valve implantation (TAVI) and endovascular aortic repair (EVAR) are increasingly being used as therapeutic options for patients with severe aortic stenosis who are ineligible for surgery and who have aortic aneurysm with suitable anatomical features. These procedures can be associated with severe complications, especially related to vascular access and the use of a large introducer sheath (from 18 to 24 French [Fr]). In this article we describe possible vascular complications emerging during TAVI and EVAR and their appropriate management, beginning with patient selection, the correct way to perform vessel puncture and the use of a vascular closure device, up to the recently proposed cross-over technique, which is thought to minimise the risk of dangerous consequences of vascular damage.

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