Penaeus monodon SERPIN, PmSERPIN6, is implicated in the shrimp innate immunity

2010 ◽  
Vol 29 (5) ◽  
pp. 890-898 ◽  
Author(s):  
Teerada Homvises ◽  
Anchalee Tassanakajon ◽  
Kunlaya Somboonwiwat
2014 ◽  
Vol 44 (1) ◽  
pp. 163-172 ◽  
Author(s):  
Tracy H.T. Ma ◽  
John A.H. Benzie ◽  
Jian-Guo He ◽  
Cheng-Bo Sun ◽  
Siuming F. Chan

2019 ◽  
Vol 78 ◽  
pp. 02002
Author(s):  
Liang Zhou ◽  
Guoqiang Li ◽  
Anguo Li ◽  
Yang Jiao ◽  
Jianhua Huang ◽  
...  

Crustins are crucial antimicrobial peptides in shrimp and play very important roles in innate immunity. In this research, a Type I crustin from Penaeus monodon (CarcininPm1) contained 108 residues was studied. The first 16 residues are signal peptide. It contained ten cysteines but did not form an intact whey acidic protein (WAP) domain. CarcininPm1 was observed to widely distribute in all tissues, while highly expressed in intestine. The expression level of CarcininPm1 in hepatopancreas was up-regulated 12- 20 times during 4-12h post challenged by Vibrio parahaemolyticus. And the transcription in heart, stomach and gills was also significantly enhanced at 4h post challenge. The mature peptide was expressed successfully in Eschericha coli by fusing to a SUMO protein, with protein production around 8 mg/mL. After cleavage with SUMO protease, carcininPm1 was obtained indicating its potential applications.


2016 ◽  
Vol 53 ◽  
pp. 114 ◽  
Author(s):  
Napol Kaewkascholkul ◽  
Kulwadee Somboonviwat ◽  
Ikuo Hirono ◽  
Anchalee Tassanakajon ◽  
Kunlaya Somboonwiwat

2009 ◽  
Vol 138 (33) ◽  
pp. 428-430
Author(s):  
Luke A.J. O'Neill
Keyword(s):  

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