Effect of the 2006 U.S. Donor Heart Allocation Policy Change on Waitlist Complications and Post-Transplant Mortality Among Candidates Supported With Mechanical Circulatory Support

2015 ◽  
Vol 34 (4) ◽  
pp. S94
Author(s):  
O. Wever-Pinzon ◽  
M. Farr ◽  
Y. Naka ◽  
H. Takayama ◽  
I. George ◽  
...  
Keyword(s):  
Policy Change ◽  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
Donor Heart ◽  
Allocation Policy ◽  
Post Transplant

scholarly journals Post-transplant outcome in patients bridged to transplant with temporary mechanical circulatory support devices

2019 ◽  
Vol 38 (8) ◽  
pp. 858-869 ◽  
Author(s):  
Michael Yaoyao Yin ◽  
Omar Wever-Pinzon ◽  
Mandeep R. Mehra ◽  
Craig H. Selzman ◽  
Alice E. Toll ◽  
...  
Keyword(s):  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
Transplant Outcome ◽  
Post Transplant ◽  
Mechanical Circulatory Support Devices ◽  
Support Devices

An updated estimate of post‐transplant survival after implementation of the new donor heart allocation policy

2021 ◽  
Author(s):  
Kevin A. Lazenby ◽  
Nikhil Narang ◽  
Kenley M. Pelzer ◽  
Gege Ran ◽  
William F. Parker
Keyword(s):  
Donor Heart ◽  
Allocation Policy ◽  
Transplant Survival ◽  
Post Transplant

Impact of mechanical circulatory support on post-transplant stroke risk

2021 ◽  
Vol 44 (10) ◽  
pp. 675-680
Author(s):  
Nandini Nair ◽  
Shengping Yang ◽  
Enrique Gongora
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Mechanical Circulatory Support ◽  
Stroke Risk ◽  
Total Artificial Heart ◽  
Circulatory Support ◽  
Study Cohort ◽  
Mechanical Support ◽  
Ischemic Time ◽  
Post Transplant

The effect of type of mechanical circulatory support on stroke risk during the early post-transplant period remains undefined in patients bridged to transplant. This study assesses if the type of circulatory support device affects stroke risk in this population. The study cohort of 4257 adult patients bridged with mechanical support to cardiac transplant were derived from the UNOS transplant registry data. Risk factors assessed were age, gender, ischemic time, diabetes (recipient), durable mechanical support at listing and mechanical ventilation pre-transplant. Descriptive statistics were used to describe characteristics of the study cohort. Univariate logistic regression was used to test if there is a significant association between stroke event and all the potential risk factors. Multivariate logistic regression was used to test such associations while adjusting for all other risk factors. Odds ratios (ORs) and their 95% confidence intervals (CIs) in parenthesis, were calculated. p < 0.05 was considered significant. Patients on Extracorporeal membrane oxygenation (ECMO) had the highest risk of stroke immediately post-transplant prior to discharge (OR 3.03, {1.16, 7.95}) followed by Total Artificial Heart (TAH) (OR 2.03, {1.01, 4.07) as compared to those only on a Left Ventricular Assist Device (LVAD). Ischemic time (OR 1.3 {1.09, 1.45}) and diabetes (OR 1.8 {1.29, 2.51}) were significant risk factors. Patients on ECMO and TAH had a 203% and 103% increase respectively in the odds of having a stroke prior to discharge as compared to those only on LVADS.

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