scholarly journals Short-term outcomes of laparoscopic versus open hepatectomy in the elderly patient: systematic review and meta-analysis

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S828
Author(s):  
K. Verkoulen ◽  
N. Hildebrand ◽  
M. Dewulf ◽  
D. Heise ◽  
F. Ulmer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Elderly Patient ◽  
Meta Analysis ◽  
The Elderly ◽  
Short Term ◽  
Open Hepatectomy

scholarly journals Short-term outcomes of laparoscopic versus open hepatectomy in the elderly patient: systematic review and meta-analysis

HPB ◽  
2021 ◽  
Author(s):  
Nicole Hildebrand ◽  
Koen Verkoulen ◽  
Maxime Dewulf ◽  
Daniel Heise ◽  
Florian Ulmer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Elderly Patient ◽  
Meta Analysis ◽  
The Elderly ◽  
Short Term ◽  
Open Hepatectomy

scholarly journals Impact of short-term exposure to extreme temperatures on diabetes mellitus morbidity and mortality? A systematic review and meta-analysis

2021 ◽  
Author(s):  
Xuping Song ◽  
Liangzhen Jiang ◽  
Dongdong Zhang ◽  
Xinyi Wang ◽  
Yan Ma ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Meta Analysis ◽  
Heat Exposure ◽  
The Elderly ◽  
Morbidity And Mortality ◽  
Cochrane Library ◽  
Extreme Temperatures ◽  
Short Term ◽  
Short Term Exposure

Abstract The relationship between diabetes mellitus and short-term exposure to extreme temperatures remains controversial. A systematic review and meta-analysis were performed to assess the association between extreme temperatures and diabetes mellitus morbidity and mortality. PubMed, Embase, the Cochrane Library, Web of Science and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) were searched since inception to January 1, 2019, and updated on November 17, 2020. The results were combined using random effects model and reported as relative risk (RR) with 95% confidence interval (CI). 32 studies met the included criteria. (1) Both heat and cold exposures have impact on diabetes. (2) For heat exposure, the subgroup analysis revealed that the effect on diabetes mortality (RR = 1.139, 95% CI: 1.089–1.192) was higher than morbidity (RR = 1.012, 95% CI: 1.004–1.019). (3) With the increase of definition threshold, the impact of heat exposure on diabetes rised. (4) A stronger association between heat exposure and diabetes was observed in the elderly (≥ 60 years old) (RR = 1.040, 95% CI: 1.017–1.064). In conclusion, both short-term exposure to heat and cold temperatures have impact on diabetes. The elderly is the vulnerable population of diabetes exposure to heat temperature. Developing definitions of heatwaves at the regional level are suggested.

scholarly journals Ambient temperature and cardiovascular mortality: a systematic review and meta-analysis

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3574 ◽  
Author(s):  
Mohammad Taghi Moghadamnia ◽  
Ali Ardalan ◽  
Alireza Mesdaghinia ◽  
Abbas Keshtkar ◽  
Kazem Naddafi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cold Exposure ◽  
Cardiovascular Mortality ◽  
Meta Analysis ◽  
Heat Exposure ◽  
The Elderly ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Short Term ◽  
Relationship Of

Introduction Our study aims at identifying and quantifying the relationship between the cold and heat exposure and the risk of cardiovascular mortality through a systematic review and meta-analysis. Material and Methods A systematic review and meta-analysis were conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Peer-reviewed studies about the temperature and cardiovascular mortality were retrieved in the MEDLINE, Web of Science, and Scopus databases from January 2000 up to the end of 2015. The pooled effect sizes of short-term effect were calculated for the heat exposure and cold exposure separately. Also, we assessed the dose–response relationship of temperature-cardiovascular mortality by a change in units of latitudes, longitude, lag days and annual mean temperature by meta-regression. Result After screening the titles, abstracts and full texts, a total of 26 articles were included in the meta-analysis. The risk of cardiovascular mortality increased by 5% (RR, 1.055; 95% CI [1.050–1.060]) for the cold exposure and 1.3% (RR, 1.013; 95% CI [1.011–1.015]) for the heat exposure. The short-term effects of cold and heat exposure on the risk of cardiovascular mortality in males were 3.8% (RR, 1.038; 95% CI [1.034–1.043]) and 1.1%( RR, 1.011; 95% CI [1.009–1.013]) respectively. Moreover, the effects of cold and heat exposure on risk of cardiovascular mortality in females were 4.1% (RR, 1.041; 95% CI [1.037–1.045]) and 1.4% (RR, 1.014; 95% CI [1.011–1.017]) respectively. In the elderly, it was at an 8.1% increase and a 6% increase in the heat and cold exposure, respectively. The greatest risk of cardiovascular mortality in cold temperature was in the 14 lag days (RR, 1.09; 95% CI [1.07–1.010]) and in hot temperatures in the seven lag days (RR, 1.14; 95% CI [1.09–1.17]). The significant dose–response relationship of latitude and longitude in cold exposure with cardiovascular mortality was found. The results showed that the risk of cardiovascular mortality increased with each degree increased significantly in latitude and longitude in cold exposure (0.2%, 95% CI [0.006–0.035]) and (0.07%, 95% CI [0.0003–0.014]) respectively. The risk of cardiovascular mortality increased with each degree increase in latitude in heat exposure (0.07%, 95% CI [0.0008–0.124]). Conclusion Our findings indicate that the increase and decrease in ambient temperature had a relationship with the cardiovascular mortality. To prevent the temperature- related mortality, persons with cardiovascular disease and the elderly should be targeted. The review has been registered with PROSPERO (registration number CRD42016037673).

Laparoscopic versus open hepatectomy for malignant liver tumours in the elderly: systematic review and meta-analysis

2021 ◽  
Author(s):  
Ali Yasen Y. Mohamedahmed ◽  
Shafquat Zaman ◽  
Mohamed Albendary ◽  
Jenny Wright ◽  
Hiba Abdalla ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
The Elderly ◽  
Liver Tumours ◽  
Open Hepatectomy ◽  
Malignant Liver

Exercise interventions in lateral elbow tendinopathy have better outcomes than passive interventions, but the effects are small: a systematic review and meta-analysis of 2123 subjects in 30 trials

2020 ◽  
pp. bjsports-2020-102525
Author(s):  
Stefanos Karanasios ◽  
Vasileios Korakakis ◽  
Rod Whiteley ◽  
Ioannis Vasilogeorgis ◽  
Sarah Woodbridge ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Short Term ◽  
Lateral Elbow ◽  
Long Term Follow Up ◽  
Wait And See ◽  
Lateral Elbow Tendinopathy

ObjectiveTo evaluate the effectiveness of exercise compared with other conservative interventions in the management of lateral elbow tendinopathy (LET) on pain and function.DesignSystematic review and meta-analysis.MethodsWe used the Cochrane risk-of-bias tool 2 for randomised controlled trials (RCTs) to assess risk of bias and the Grading of Recommendations Assessment, Development and Evaluation methodology to grade the certainty of evidence. Self-perceived improvement, pain intensity, pain-free grip strength (PFGS) and elbow disability were used as primary outcome measures.Eligibility criteriaRCTs assessing the effectiveness of exercise alone or as an additive intervention compared with passive interventions, wait-and-see or injections in patients with LET.Results30 RCTs (2123 participants, 5 comparator interventions) were identified. Exercise outperformed (low certainty) corticosteroid injections in all outcomes at all time points except short-term pain reduction. Clinically significant differences were found in PFGS at short-term (mean difference (MD): 12.15, (95% CI) 1.69 to 22.6), mid-term (MD: 22.45, 95% CI 3.63 to 41.3) and long-term follow-up (MD: 18, 95% CI 11.17 to 24.84). Statistically significant differences (very low certainty) for exercise compared with wait-and-see were found only in self-perceived improvement at short-term, pain reduction and elbow disability at short-term and long-term follow-up. Substantial heterogeneity in descriptions of equipment, load, duration and frequency of exercise programmes were evident.ConclusionsLow and very low certainty evidence suggests exercise is effective compared with passive interventions with or without invasive treatment in LET, but the effect is small.PROSPERO registration numberCRD42018082703.

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