Prognostic value of androgen receptor expression and molecular alterations in metastatic triple negative or low hormone receptor breast carcinomas

2021 ◽  
Author(s):  
Tiansheng Shen ◽  
Lai Wei ◽  
Xiaoxian Li ◽  
Anil V. Parwani ◽  
Zaibo Li
Keyword(s):  
Androgen Receptor ◽  
Hormone Receptor ◽  
Prognostic Value ◽  
Triple Negative ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Breast Carcinomas ◽  
Molecular Alterations

scholarly journals IMMUNOHISTOCHEMICAL EXPRESSION OF ANDROGEN RECEPTOR IN TRIPLE NEGATIVE BREAST CARCINOMA AT ARMED FORCES INSTITUTE OF PATHOLOGY, RAWALPINDI

2021 ◽  
Vol 71 (1) ◽  
pp. 7-11
Author(s):  
Amna Ameer ◽  
Farhan Akhtar ◽  
Hafeez Ud Din ◽  
Rabia Ahmad
Keyword(s):  
Androgen Receptor ◽  
Breast Carcinoma ◽  
Triple Negative ◽  
Histological Grade ◽  
Armed Forces ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Breast Carcinomas ◽  
Immunohistochemical Expression ◽  
Triple Negative Breast Carcinoma

Objective: To determine the frequency of immunohistochemical expression of androgen receptor in triplenegative breast carcinoma. Study Design: Cross sectional study. Duration and Place of Study: This study included 30 cases confirmed as triple negative breast carcinoma atArmed Forces Institute of Pathology Rawalpindi, from Jan to Jul 2018. Methodology: Anti-androgen receptor antibody was applied and assessed. Positive expression was defined asgreater and equal to 10% nuclear immunostaining. SPSS-24 was used for analyzing data. Results: Out of 30 cases of triple negative breast carcinoma (TNBC), all patients were female. Patients’ agesranged between 21-72 years with a mean age of 46.35 years and a standard deviation of ± 13.4. Androgen receptor expression was positive in 8 cases (27%) of all triple negative breast carcinomas. Out of these androgen receptor (AR) triple negative breast carcinomas; all 8 cases were of histological subtype invasive ductal (mammary) carcinoma, non special type, 7 cases (23%) were of histological grade 3 and 1 was of histological grade 2. Conclusion: Androgen receptor expression is observed in 8 cases (27%) of triple negative breast carcinoma cases. Such patients can be selected as candidates for anti- androgen receptor targeted therapy.

Clinical significance of immunohistochemical androgen receptor expression in triple negative breast cancer

The Breast ◽  
2017 ◽  
Vol 32 ◽  
pp. S45-S46
Author(s):  
E. Sakata ◽  
A. Makino ◽  
H. Miyahira ◽  
Y. Endo ◽  
H. Shibuya ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Clinical Significance ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Receptor Expression ◽  
Androgen Receptor Expression

scholarly journals Androgen receptor expression in triple negative breast cancer and its relationship to prognostic factors

2017 ◽  
Vol 27 (3) ◽  
pp. 199-205
Author(s):  
Maximiliano Cassilha Kneubil ◽  
◽  
Alessandra Eifler Guerra Godoy ◽  
Guilherme Portela Coelho ◽  
Rafael Grochot ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Androgen Receptor ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Receptor Expression ◽  
Androgen Receptor Expression

Abstract P3-04-07: Androgen receptor expression in triple negative breast cancer

2015 ◽  
Author(s):  
Hannah Gilmore ◽  
Vinay Varadan ◽  
Nicole Williams ◽  
Cheryl L Thompson ◽  
Stephanie Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Receptor Expression ◽  
Androgen Receptor Expression

scholarly journals Androgen Receptor Expression in Early Triple-Negative Breast Cancer: Clinical Significance and Prognostic Associations

Cancers ◽  
2014 ◽  
Vol 6 (3) ◽  
pp. 1351-1362 ◽  
Author(s):  
Mirco Pistelli ◽  
Miriam Caramanti ◽  
Tommasina Biscotti ◽  
Alfredo Santinelli ◽  
Alessandra Pagliacci ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Clinical Significance ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Receptor Expression ◽  
Androgen Receptor Expression
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