A new unified conceptual framework involving maintenance energy, metabolism and toxicity for research on degradation of organic pollutants

Continued improvement through genetic selection and the use of entire males has resulted in pigs with considerable potential for lean tissue growth rate. These animals have, however, lower appetites and this suggests that there may be considerable differences in the partition and in the efficiency of utilisation of dietary nutrients, compared with those previously recommended by ARC (1981). There may also be differences in energy expenditure since Campbell and Taverner (1988) and Rao and McCracken (1990) have suggested that animals of high potential for lean tissue growth rate have higher maintenance energy requirements. There is little information on the energy requirements of pigs of different growth potential and the present experiments were designed to evaluate the effects of feeding levels on nutrient partition and energy metabolism of pigs of different body weights and sex.

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Simulation of energy metabolism in the simple-stomached animal

British Journal Of Nutrition ◽

10.1079/bjn19780034 ◽

1978 ◽

Vol 39 (2) ◽

pp. 235-254 ◽

Cited By ~ 30

Author(s):

A. R. Schulz

Keyword(s):

Energy Metabolism ◽

Adenosine Triphosphate ◽

Metabolic Pathways ◽

Close Agreement ◽

Energy Requirement ◽

Maintenance Energy ◽

Quasi Steady State ◽

Computer Programme ◽

Energy Retention ◽

Maintenance Energy Requirement

1. A computer programme is described which simulates energy metabolism in the whole animal. Simulation was based on representation of the animal as a quasi-steady-state system.2. Input for the programme consisted of the chemical composition of the diet and an estimate of either the maintenance energy requirement or an estimate of energy retention.3. Simulation was performed by estimating the yield of adenosine triphosphate in the major metabolic pathways operative in simple-stomached animals, and on the utilization of adenosine triphosphate in major anabolic processes.x4. Results obtained from simulation were in close agreement with experimental observations reported by McCracken (1975).

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Mitochondrial matrix calcium ions regulate energy production in myocardium: A cytochemical study

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100134429 ◽

1990 ◽

Vol 48 (2) ◽

pp. 166-167

Author(s):

W.A. Jacob ◽

R. Hertsens ◽

A. Van Bogaert ◽

M. De Smet

Keyword(s):

Energy Metabolism ◽

Calcium Ions ◽

Energy Production ◽

Regulation Of Respiration ◽

Free Calcium ◽

Mitochondrial Matrix ◽

Cytochemical Study ◽

Nmr Techniques

In the past most studies of the control of energy metabolism focus on the role of the phosphorylation potential ATP/ADP.Pi on the regulation of respiration. Studies using NMR techniques have demonstrated that the concentrations of these compounds for oxidation phosphorylation do not change appreciably throughout the cardiac cycle and during increases in cardiac work. Hence regulation of energy production by calcium ions, present in the mitochondrial matrix, has been the object of a number of recent studies.Three exclusively intramitochondnal dehydrogenases are key enzymes for the regulation of oxidative metabolism. They are activated by calcium ions in the low micromolar range. Since, however, earlier estimates of the intramitochondnal calcium, based on equilibrium thermodynamic considerations, were in the millimolar range, a physiological correlation was not evident. The introduction of calcium-sensitive probes fura-2 and indo-1 made monitoring of free calcium during changing energy metabolism possible. These studies were performed on isolated mitochondria and extrapolation to the in vivo situation is more or less speculative.

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A conceptual framework for advanced practice: an action research project operationalizing anadvanced practitioner/consultant nurse role

Journal of Clinical Nursing ◽

10.1046/j.1365-2702.1997.00143.x ◽

1997 ◽

Vol 6 (3) ◽

pp. 179-190 ◽

Cited By ~ 20

Author(s):

Kim Manley

Keyword(s):

Action Research ◽

Conceptual Framework ◽

Advanced Practice ◽

Action Research Project ◽

Research Project ◽

Nurse Role

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Evaluating research in developmental disabilities: a conceptual framework for reviewing treatment outcomes

Developmental Medicine & Child Neurology ◽

10.1017/s0012162299000110 ◽

1999 ◽

Vol 41 (1) ◽

pp. 55-59 ◽

Cited By ~ 51

Author(s):

Charlene Butler ◽

Henry Chambers ◽

Murray Goldstein ◽

Susan Harris ◽

Judy Leach ◽

...

Keyword(s):

Developmental Disabilities ◽

Conceptual Framework ◽

Treatment Outcomes

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Understanding Why Older People Develop a Wish to Die

Crisis ◽

10.1027/0227-5910/a000078 ◽

2011 ◽

Vol 32 (4) ◽

pp. 204-216 ◽

Cited By ~ 52

Author(s):

M. L. Rurup ◽

H. R. W. Pasman ◽

J. Goedhart ◽

D. J. H. Deeg ◽

A. J. F. M. Kerkhof ◽

...

Keyword(s):

Older People ◽

Cohort Studies ◽

Conceptual Framework ◽

Life Events ◽

Traumatic Life Events ◽

Quantitative Studies ◽

Wish To Die ◽

Open Coding ◽

Death Wishes ◽

Depth Interviews

Background: Quantitative studies in several European countries showed that 10–20% of older people have or have had a wish to die. Aims: To improve our understanding of why some older people develop a wish to die. Methods: In-depth interviews with people with a wish to die (n = 31) were carried out. Through open coding and inductive analysis, we developed a conceptual framework to describe the development of death wishes. Respondents were selected from two cohort studies. Results: The wish to die had either been triggered suddenly after traumatic life events or had developed gradually after a life full of adversity, as a consequence of aging or illness, or after recurring depression. The respondents were in a situation they considered unacceptable, yet they felt they had no control to change their situation and thus progressively “gave up” trying. Recurring themes included being widowed, feeling lonely, being a victim, being dependent, and wanting to be useful. Developing thoughts about death as a positive thing or a release from problems seemed to them like a way to reclaim control. Conclusions: People who wish to die originally develop thoughts about death as a positive solution to life events or to an adverse situation, and eventually reach a balance of the wish to live and to die.

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