In vitro activity of a novel compound, Mul-1867, against clinically significant fungi Candida spp. and Aspergillus spp.

2017 ◽  
Vol 50 (1) ◽  
pp. 47-54
Author(s):  
George Tetz ◽  
Michael Cynamon ◽  
Gregory Hendricks ◽  
Daria Vikina ◽  
Victor Tetz
1999 ◽  
Vol 44 (5) ◽  
pp. 697-700 ◽  
Author(s):  
M. Chávez ◽  
S. Bernal ◽  
A. Valverde ◽  
M. J. Gutierrez ◽  
G. Quindós ◽  
...  

2017 ◽  
Vol 72 (5) ◽  
pp. 1355-1358 ◽  
Author(s):  
Dina A. Boikov ◽  
Jeffrey B. Locke ◽  
Kenneth D. James ◽  
Ken Bartizal ◽  
Jack D. Sobel

Drugs ◽  
1988 ◽  
Vol 35 (Supplement 2) ◽  
pp. 14-21 ◽  
Author(s):  
Satoshi Nakashio ◽  
Masao Nakamura

2015 ◽  
Vol 29 (10) ◽  
pp. 1628-1633 ◽  
Author(s):  
Maura Di Vito ◽  
Paola Mattarelli ◽  
Monica Modesto ◽  
Antonietta Girolamo ◽  
Milva Ballardini ◽  
...  

1996 ◽  
Vol 40 (9) ◽  
pp. 2229-2231 ◽  
Author(s):  
H M Wardle ◽  
D Law ◽  
D W Denning

We compared the in vitro activity of BMS-181184, the first compound of a new class of antifungal agents, the pradimicins, with those of fluconazole and amphotericin B against 64 clinical isolates of Candida species. MICs were determined by a microdilution method with high resolution medium for BMS-181184 and fluconazole and antibiotic medium no. 3 with 2% glucose for amphotericin B. MICs of BMS-181184 for all yeasts were in the range of 0.78 to 12.5 micrograms/ml. BMS-181184 was active against isolates resistant to other antifungal agents, consistent with a novel mode of action. Minimum fungicidal concentrations for 16 isolates showed that BMS-181184 was fungicidal. Clinical studies are now required to confirm its activity.


1997 ◽  
Vol 41 (10) ◽  
pp. 2310-2311 ◽  
Author(s):  
D Law ◽  
C B Moore ◽  
D W Denning

The in vitro activity of Schering 56592, a new azole drug, was compared with those of fluconazole and itraconazole against 103 isolates of Candida comprising 10 different species. Schering 56592 was more active than itraconazole and fluconazole, and it was active against many fluconazole-resistant isolates.


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