scholarly journals Insertion sequence mediated imipenem resistance in Indian anaerobic bacterial isolates and susceptibility trends in Bacteroides fragilis

2021 ◽  
Vol 58 ◽  
pp. 21003964
Author(s):  
Anshul Sood ◽  
Pallab Ray ◽  
Archana Angrup
2009 ◽  
Vol 34 (6) ◽  
pp. 608-609
Author(s):  
Giuliana Lo Cascio ◽  
Laura Macaccaro ◽  
Anna Rita Centonze ◽  
Jozef Sóki ◽  
Roberta Fontana ◽  
...  

1999 ◽  
Vol 43 (11) ◽  
pp. 2808-2810 ◽  
Author(s):  
Kikuo Yamazoe ◽  
Naoki Kato ◽  
Haru Kato ◽  
Kaori Tanaka ◽  
Yoshihiro Katagiri ◽  
...  

ABSTRACT The cfiA gene, encoding an imipenem-hydrolyzing metallo-β-lactamase produced by Bacteroides fragilis, and insertion-like elements were detected by PCR amplification withB. fragilis strains isolated in Japan. The cfiAgene was found in 1.9 and 4.1% of the imipenem-susceptible B. fragilis isolates collected from 1987 to 1988 and from 1992 to 1994, respectively. Insertion-like elements adjacent to thecfiA gene were found in all nine metallo-β-lactamase-producing imipenem-resistant strains tested but not in nine cfiA-positive strains with no detectable metallo-β-lactamase activity.


2008 ◽  
Vol 52 (11) ◽  
pp. 4115-4120 ◽  
Author(s):  
Raffaele Zarrilli ◽  
Domenico Vitale ◽  
Anna Di Popolo ◽  
Maria Bagattini ◽  
Ziad Daoud ◽  
...  

ABSTRACT We investigated the basis of the carbapenem resistance of 17 multidrug-resistant Acinetobacter baumannii clinical isolates collected from 2004 to 2005 at the Saint George University Hospital in Beirut, Lebanon. A. baumannii isolates were clonally related and were susceptible to colistin and trimethoprim-sulfamethoxazole, susceptible or intermediate to ampicillin-sulbactam and meropenem, and resistant to all other antimicrobials. Conjugation experiments demonstrated that resistance to imipenem could be transferred along with a plasmid containing the carbapenem-hydrolyzing oxacillinase bla OXA-58 gene. The plasmid that we called pABIR was 29,823 bp in size and showed a novel mosaic structure composed of two origins of replication, four insertion sequence (IS) elements, and 28 open reading frames. The bla OXA-58 gene was flanked by IS18 and ISAba3 elements at the 5′ and 3′ ends, respectively. The production of the carbapenem-hydrolyzing oxacillinase OXA-58 was apparently the only mechanism for carbapenem resistance in A. baumannii isolates causing the outbreak at the Lebanese Hospital.


1986 ◽  
Vol 30 (5) ◽  
pp. 645-648 ◽  
Author(s):  
G J Cuchural ◽  
M H Malamy ◽  
F P Tally

1992 ◽  
Vol 45 (4) ◽  
pp. 542-547 ◽  
Author(s):  
KAORI BANDOH ◽  
KUNITOMO WATANABE ◽  
YOSHINORI MUTO ◽  
YASUNORI TANAKA ◽  
NAOKI KATO ◽  
...  

2001 ◽  
Vol 52 (2-3) ◽  
pp. 271-280 ◽  
Author(s):  
Elisabeth Nagy ◽  
J. Sóki ◽  
Edit Urbán ◽  
Ildikó Sz'ke ◽  
Eleonóra Fodor ◽  
...  

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