Synthesis, characterization and antimicrobial activity of a novel chitosan Schiff bases based on heterocyclic moieties

2020 ◽  
Vol 153 ◽  
pp. 492-501 ◽  
Author(s):  
Amira A. Hamed ◽  
Ismail A. Abdelhamid ◽  
Gamal R. Saad ◽  
Nadia A. Elkady ◽  
Maher Z. Elsabee
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Bases ◽  
Chitosan Schiff Bases

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF 3-FORMYL INDOLE BASED SCHIFF BASES

2018 ◽  
Vol 7 (6) ◽  
Author(s):  
Singh Gurvinder ◽  
Singh Prabhsimran ◽  
Dhawan R. K.
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Analysis ◽  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Biological Evaluation ◽  
Fungal Strain ◽  
Bacterial Strains ◽  
Standard Drug ◽  
Gram Negative ◽  
E Coli

In order to develop new antimicrobial agents, a series of 3-formyl indole based Schiff bases were synthesized by reacting 3-formyl indole(indole-3-carboxaldehyde) with substituted aniline taking ethanol as solvent. The reaction was carried in the presence of small amount of p-toluene sulphonic acid as catalyst.All the synthesized compounds were characterized by IR, 1H-NMR spectral analysis. All the synthesized compounds were evaluated for antimicrobial activity against two gram positive bacterial strains (B. subtilisand S. aureus) and two gram negative bacterial strains (P. aeruginosaand E. coli) and one fungal strain (C. albicans). All the synthesized compounds were found to have moderate to good antimicrobial activity. The  standard drug amoxicillin, fluconazole were used for antimicrobial activity. Among the synthesized compounds, the maximum antimicrobial activity was shown by compounds GS04, GS07, GS08 and GS10.

scholarly journals Synthesis of new Cadmium(II) Complexes of Schiff Bases as Alkaline Phosphatase Inhibitors and their Antimicrobial Activity

2021 ◽  
pp. 103308
Author(s):  
Rana Muhammad Irfan ◽  
Muhammad Ashraf Shaheen ◽  
Muhammad Saleem ◽  
Muhammad Nawaz Tahir ◽  
Khurram Shahzad Munawar ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Alkaline Phosphatase ◽  
Schiff Bases ◽  
Phosphatase Inhibitors

Synthesis and characterization of novel dimerics-triazine derivatives as potential anti-bacterial agents against MDR clinical isolates

2018 ◽  
Vol 42 (13) ◽  
pp. 10676-10688 ◽  
Author(s):  
Doaa R. Ramadan ◽  
Aly A. Elbardan ◽  
Adnan A. Bekhit ◽  
Ayman El-Faham ◽  
Sherine N. Khattab
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Bases ◽  
Mammalian Cells ◽  
High Selectivity ◽  
Bacterial Activity ◽  
Selectivity Index ◽  
Synthesis And Characterization ◽  
Triazine Derivatives ◽  
Ampicillin Trihydrate

Several dimerics-triazine Schiff bases displayed more potent anti-bacterial activity compared with ampicillin trihydrate. They revealed significantly low MIC values towards the tested MDR strains and showed a high selectivity index towards antimicrobial activity againstK. pneumoniaeandMRSA1compared to mammalian cells.

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