Left ventricular mass and risk of cardiovascular events and all-cause death among ethnic Chinese—The Chin-Shan Community Cardiovascular Cohort study

Preterm birth and epicardial fat thickness (EFT) constitute novel risk factors for the onset of future adverse cardiovascular events. In total, 30 ex-extremely low birth weight (ex-ELBW) subjects (10 males, 20 females, aged 17–28) were enrolled and compared with 30 healthy peers. EFT was significantly higher (8.7±0.7 mm v. 5.6±0.9 mm; P<0.001) in ex-ELBW than in controls and was correlated with birth weight (r=−0.47, P=0.0009), gestational age (r=−0.39, P=0.03) and cardiac left ventricular mass (r=0.51, P=0.004). When excluding the influence of body mass index, birth weight was the sole remaining determinant of EFT, irrespective of gestational age (r=−0.37, P=0.04). The same findings when excluding the possible influence of blood pressure values on the cardiac structures (r=−0.40, P=0.028). In conclusion, EFT is significantly higher in former preterm subjects and is likewise associated with an increase in left ventricular mass. In view of the acknowledged correlation between the latter and an increased incidence of cardiovascular diseases, EFT appears to be an easy-to-measure tool capable of predicting the likely development of future adverse cardiovascular events in these subjects.

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P-238 Left Ventricular Mass volume Ratio and Hazard of Adverse Cardiovascular Events

CVD Prevention and Control ◽

10.1016/s1875-4570(09)60430-7 ◽

2009 ◽

Vol 4 ◽

pp. S119

Author(s):

Michael Chuang ◽

Philimon Gona ◽

Carol J. Salton ◽

Christopher J. O'Donnell ◽

Warren J. Manning

Keyword(s):

Left Ventricular Mass ◽

Cardiovascular Events ◽

Volume Ratio ◽

Left Ventricular ◽

Ventricular Mass ◽

Mass Volume

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Indexation of left ventricular mass to predict adverse clinical outcomes in pre-dialysis patients with chronic kidney disease: KoreaN cohort study of the outcome in patients with chronic kidney disease

PLoS ONE ◽

10.1371/journal.pone.0233310 ◽

2020 ◽

Vol 15 (5) ◽

pp. e0233310

Author(s):

Sung Woo Lee ◽

Hyang Ki Min ◽

Dong-Wan Chae ◽

Kook-Hwan Oh ◽

Curie Ahn ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Cohort Study ◽

Kidney Disease ◽

Clinical Outcomes ◽

Left Ventricular Mass ◽

Left Ventricular ◽

Dialysis Patients ◽

Ventricular Mass

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Left Ventricular Mass at MRI and Long-term Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis (MESA)

Radiology ◽

10.1148/radiol.2019182871 ◽

2019 ◽

Vol 293 (1) ◽

pp. 107-114 ◽

Cited By ~ 7

Author(s):

Nadine Kawel-Boehm ◽

Richard Kronmal ◽

John Eng ◽

Aaron Folsom ◽

Gregory Burke ◽

...

Keyword(s):

Left Ventricular Mass ◽

Cardiovascular Events ◽

Left Ventricular ◽

Ethnic Study ◽

Ventricular Mass

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BP in Dialysis: Results of a Pilot Study

Journal of the American Society of Nephrology ◽

10.1681/asn.2017020135 ◽

2017 ◽

Vol 29 (1) ◽

pp. 307-316 ◽

Cited By ~ 23

Author(s):

Dana C. Miskulin ◽

Jennifer Gassman ◽

Ronald Schrader ◽

Ambreen Gul ◽

Manisha Jhamb ◽

...

Keyword(s):

Left Ventricular Mass ◽

Confidence Intervals ◽

Cardiovascular Events ◽

Moving Average ◽

Left Ventricular ◽

Full Scale ◽

Major Adverse Cardiovascular Events ◽

Ventricular Mass ◽

Potential Benefits ◽

Rate Ratios

The optimal BP target for patients receiving hemodialysis is unknown. We randomized 126 hypertensive patients on hemodialysis to a standardized predialysis systolic BP of 110–140 mmHg (intensive arm) or 155–165 mmHg (standard arm). The primary objectives were to assess feasibility and safety and inform the design of a full-scale trial. A secondary objective was to assess changes in left ventricular mass. Median follow-up was 365 days. In the standard arm, the 2-week moving average systolic BP did not change significantly during the intervention period, but in the intensive arm, systolic BP decreased from 160 mmHg at baseline to 143 mmHg at 4.5 months. From months 4–12, the mean separation in systolic BP between arms was 12.9 mmHg. Four deaths occurred in the intensive arm and one death occurred in the standard arm. The incidence rate ratios for the intensive compared with the standard arm (95% confidence intervals) were 1.18 (0.40 to 3.33), 1.61 (0.87 to 2.97), and 3.09 (0.96 to 8.78) for major adverse cardiovascular events, hospitalizations, and vascular access thrombosis, respectively. The intensive and standard arms had similar median changes (95% confidence intervals) in left ventricular mass of −0.84 (−17.1 to 10.0) g and 1.4 (−11.6 to 10.4) g, respectively. Although we identified a possible safety signal, the small size and short duration of the trial prevent definitive conclusions. Considering the high risk for major adverse cardiovascular events in patients receiving hemodialysis, a full-scale trial is needed to assess potential benefits of intensive hypertension control in this population.

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