Heart rate variability in the frequency domain in chronic Chagas disease: Correlation of autonomic dysfunction with variables of daily clinical practice

2011 ◽  
Vol 150 (3) ◽  
pp. 357-358 ◽  
Author(s):  
Fabiana C. Gerbi ◽  
Jorge T. Takahashi ◽  
Augusto Cardinalli-Neto ◽  
Paulo Roberto Nogueira ◽  
Reinaldo B. Bestetti
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Clinical Practice ◽  
Frequency Domain ◽  
Chagas Disease ◽  
Autonomic Dysfunction ◽  
Daily Clinical Practice ◽  
Chronic Chagas Disease

scholarly journals Heart rate variability: Analysis of time-domain indices in patients with chronic Chagas disease before and after an exercise program

2013 ◽  
Vol 32 (3) ◽  
pp. 219-227 ◽  
Author(s):  
Marcus Vinicius Amaral da Silva Souza ◽  
Carla Cristiane Santos Soares ◽  
Juliana Rega de Oliveira ◽  
Cláudia Rosa de Oliveira ◽  
Paloma Hargreaves Fialho ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Chagas Disease ◽  
Time Domain ◽  
Exercise Program ◽  
Heart Rate Variability Analysis ◽  
Variability Analysis ◽  
Before And After ◽  
Chronic Chagas Disease

scholarly journals Chemical Sympathectomy Restores Baroreceptor-Heart Rate Reflex and Heart Rate Variability in Rats With Chronic Nitric Oxide Deficiency

2015 ◽  
pp. 459-466 ◽  
Author(s):  
M. CHASWAL ◽  
S. DAS ◽  
J. PRASAD ◽  
A. KATYAL ◽  
M. FAHIM
Keyword(s):  
Nitric Oxide ◽  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Autonomic Dysfunction ◽  
Sympathetic Innervation ◽  
Chemical Sympathectomy ◽  
Principal Mechanism ◽  
Cardiac Autonomic Dysfunction

Nitric oxide (NO) plays a crucial role not only in regulation of blood pressure but also in maintenance of cardiac autonomic tone and its deficiency induced hypertension is accompanied by cardiac autonomic dysfunction. However, underlying mechanisms are not clearly defined. We hypothesized that sympathetic activation mediates hemodynamic and cardiac autonomic changes consequent to deficient NO synthesis. We used chemical sympathectomy by 6-hydroxydopamine to examine the influence of sympathetic innervation on baroreflex sensitivity (BRS) and heart rate variability (HRV) of chronic NG-nitro-L-arginine methyl ester (L-NAME) treated adult Wistar rats. BRS was determined from heart rate responses to changes in systolic arterial pressure achieved by intravenous administration of phenylephrine and sodium nitroprusside. Time and frequency domain measures of HRV were calculated from 5-min electrocardiogram recordings. Chronic L-NAME administration (50 mg/kg per day for 7 days orally through gavage) in control rats produced significant elevation of blood pressure, tachycardia, attenuation of BRS for bradycardia and tachycardia reflex and fall in time as well as frequency domain parameters of HRV. Sympathectomy completely abolished the pressor as well as tachycardic effect of chronic L-NAME. In addition, BRS and HRV improved after removal of sympathetic influence in chronic L-NAME treated rats. These results support the concept that an exaggerated sympathetic activity is the principal mechanism of chronic L NAME hypertension and associated autonomic dysfunction.

Impaired heart rate variability in patients with chronic Chagas' disease

1991 ◽  
Vol 121 (6) ◽  
pp. 1727-1734 ◽  
Author(s):  
Stefano Guzzetti ◽  
Daniel Iosa ◽  
Marica Pecis ◽  
Luisa Bonura ◽  
Marco Prosdocimi ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Chagas Disease ◽  
Chronic Chagas Disease

Cardiac Dysrhythmias and Autonomic Dysfunction in Chronic Spinal Cord Injury: A 24-Hour Holter Monitoring and Heart Rate Variability Study

1999 ◽  
Vol 13 (4) ◽  
pp. 235-241 ◽  
Author(s):  
Gülçin Demirel ◽  
Seref Demirel ◽  
Hürriyet Yilmaz ◽  
Vakur Akkaya ◽  
Dursun Atilgan ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Heart Rate ◽  
Spinal Cord Injury ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Autonomic Dysfunction ◽  
Time Domain ◽  
Chronic Spinal Cord Injury ◽  
Cardiac Dysrhythmias ◽  
Cord Injury

The purpose of this study is to evaluate chronic spinal cord injury (SCI) patients for the incidence of cardiac dysrhythmias and the level of autonomic nervous system (ANS) dysfunction using 24-hour Holter recordings and long-term time-domain and frequency-domain heart rate variability (HRV) analysis. There was no difference be tween groups for the frequency of ventricular or supraventricular ectopics, minimal and mean heart rate, and the longest RR intervals. Maximum heart rate was lower in the quadriplegic group compared with controls (124.1 ± 11.2 vs. 139.4 ± 10.9, p < 0.05). Frequency-domain spectral analysis of high, low, total frequency powers, and ratio LF/HF showed no significant difference between groups. On time-domain analy sis SDANN (94.5 ± 26.4 vs. 131.1 ± 15.1, p < 0.0 1) and SDNN (110.1 ± 29.2 vs. 143.6 ± 19. 1, p < 0.05) were significantly lower in quadriplegics compared with controls. SDANN (74.0 ± 17.9 vs. 115.0 ± 14.2 p < 0.01) and SDNN ( 90.2 ± 21.1 vs. 130.0 ± 22.0 p < 0.05) were significantly lower in complete quadriplegics com pared with incomplete quadriplegics. When the effect of wake (07-22)-sleep (23-07) cycle on frequency-domain parameters were assessed, HF (12.38 ± 5.1 vs. 21.18 ± 8.05, p = 0.001) and TP (35.93 ± 10.5 vs. 45.68 ± 12.68, p = 0.004) showed the physiologic increase during sleep in controls, but was unchanged in quadriplegics (10.48 ± 5.39 vs. 13.35 ± 8.03, p = 0.205 and 30.67 ± 10.61 vs. 37.01 ± 17.59, p = 0.208, respectively). In paraplegics a blunted increase in HF (14.61 ± 7.69 vs. 19.85 ± 14.13, p = 0.09) and TP (38.5 ± 12.77 vs. 47.13 ± 23.08, p = 0.08) was observed. LF showed no significant change in the three groups. Heart rate circadian rhythm was preserved in all three groups (p < 0.01). We concluded that chronic complete cer vical SCI may disrupt modulatory sympathetic flow and downregulates parasympa thetic activity but causes no major arrhythmias needing treatment. Key Words: Chronic spinal cord injury—Cardiac dysrhythmia—Autonomic dysfunction-Heart rate variability.

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