Prevalence, long-term prognosis and medical alternatives for patients admitted for acute coronary syndromes and prasugrel contraindication

Ischemic heart disease is the leading cause of death in Europe among males over 45 years of age and females older than 65. The aim of the study: to evaluate the informative value of the models in ACS patients using GRACE (GR) risk score, to identify additional informative indicators for short-term and long-term prognosis following ACS, and to evaluate the prognostic reliability of the integrated model. The study included 1491 patients who in 2005 were treated for ACS in the Department of Cardiology, the Hospital of Kaunas University of Medicine. We devised an adjusted prognostic index for making short and long-term prognosis in patients with acute coronary syndromes (STEMI and NSETMI). Following adjustment of the GR scores, the prognostic value improved for STEMI patients. Ill. 2, bibl. 12, tabl. 3 (in English; abstracts in English and Lithuanian).http://dx.doi.org/10.5755/j01.eee.110.4.292

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Circulating Osteoprotegerin Levels and Long-Term Prognosis in Patients With Acute Coronary Syndromes

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2007.09.058 ◽

2008 ◽

Vol 51 (6) ◽

pp. 627-633 ◽

Cited By ~ 132

Author(s):

Torbjørn Omland ◽

Thor Ueland ◽

Anna M. Jansson ◽

Anita Persson ◽

Thomas Karlsson ◽

...

Keyword(s):

Acute Coronary Syndromes ◽

Coronary Syndromes ◽

Long Term Prognosis

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Long-term prognosis of south Asians following acute coronary syndromes

Canadian Journal of Cardiology ◽

10.1016/s0828-282x(08)70640-8 ◽

2008 ◽

Vol 24 (7) ◽

pp. 585-587 ◽

Cited By ~ 11

Author(s):

Ramya Raghavan ◽

Elham Rahme ◽

Hacene Nedjar ◽

Thao Huynh

Keyword(s):

Acute Coronary Syndromes ◽

South Asians ◽

Coronary Syndromes ◽

Long Term Prognosis

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Effect of Acarbose on Long-Term Prognosis in Acute Coronary Syndromes Patients with Newly Diagnosed Impaired Glucose Tolerance

Journal of Diabetes Research ◽

10.1155/2016/1602083 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 6

Author(s):

Peng Yun ◽

Ai-ming Du ◽

Xue-jun Chen ◽

Jing-cheng Liu ◽

Hu Xiao

Keyword(s):

Glucose Tolerance ◽

Impaired Glucose Tolerance ◽

Acute Coronary Syndromes ◽

Control Group ◽

Newly Diagnosed ◽

Adverse Cardiovascular Event ◽

Coronary Syndromes ◽

Long Term Prognosis

Objective. To investigate the effect of acarbose therapy on the long-term prognosis of patients with acute coronary syndromes (ACS) complicating newly diagnosed impaired glucose tolerance (IGT).Methodology. 135 patients hospitalized for ACS who had been newly diagnosed with IGT were randomly assigned to acarbose group (150 mg/day,n=67) or control group (no acarbose,n=68). All cases in each group were given the same elementary treatment. Mean follow-up was 2.3 years. The incidence of major adverse cardiovascular event (MACE) and carotid intima-middle thickness (CIMT) were statistically analyzed.Results. During the mean follow-up of 2.3 years, the risk of recurrent MACE in acarbose group was decreased significantly compared with that in control group (26.67% versus 46.88%,P<0.05); at the same time, thickening of the CIMT was significantly slower than the control group ((1.28 ± 0.42) mm versus (1.51 ± 0.64) mm,P<0.05).Conclusions. Acarbose can effectively reduce the risk of MACE in ACS patients with newly diagnosed IGT, simultaneously retarding the progression of carotid intima-media thickness.

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