Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature

2009 ◽  
Vol 135 (3) ◽  
pp. 231-237 ◽  
Author(s):  
Markus Schmidt-Heydt ◽  
Ahmed Abdel-Hadi ◽  
Naresh Magan ◽  
Rolf Geisen
Keyword(s):  
Gene Cluster ◽  
Water Activity ◽  
Aspergillus Flavus ◽  
Aflatoxin Biosynthesis ◽  
Biosynthesis Gene Cluster ◽  
Biosynthesis Gene ◽  
Complex Regulation

scholarly journals HypC, the Anthrone Oxidase Involved in Aflatoxin Biosynthesis

2010 ◽  
Vol 76 (10) ◽  
pp. 3374-3377 ◽  
Author(s):  
Kenneth C. Ehrlich ◽  
Ping Li ◽  
Leslie Scharfenstein ◽  
Perng-Kuang Chang
Keyword(s):  
Enzyme Activity ◽  
Gene Cluster ◽  
Gene Disruption ◽  
Open Reading Frame ◽  
Aflatoxin Biosynthesis ◽  
Biosynthesis Gene Cluster ◽  
Reading Frame ◽  
Biosynthesis Gene ◽  
Norsolorinic Acid

ABSTRACT On the basis of gene disruption and enzyme activity, hypC, an open reading frame in the region between the pksA (aflC) and nor-1 (aflD) genes in the aflatoxin biosynthesis gene cluster, encodes a 17-kDa oxidase that converts norsolorinic acid anthrone to norsolorinic acid.

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