Lack of association between two polymorphisms in the corticotropin-releasing hormone gene promoter and preterm birth in a Hispanic population

2012 ◽  
Vol 118 (2) ◽  
pp. 173-174
Author(s):  
Laura Diaz-Cueto ◽  
Pablo Dominguez-Lopez ◽  
Claudia Cordoba-Zavala ◽  
Patricia Casas-Gonzalez ◽  
Fabian Arechavaleta-Velasco
Keyword(s):  
Preterm Birth ◽  
Gene Promoter ◽  
Hispanic Population ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Predicting Risk of Preterm Birth: The Roles of Stress, Clinical Risk Factors, and Corticotropin-Releasing Hormone

2002 ◽  
Vol 4 (1) ◽  
pp. 54-64 ◽  
Author(s):  
R. Jeanne Ruiz ◽  
Judith Fullerton ◽  
Charles E. L. Brown ◽  
Donald J. Dudley
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Perceived Stress ◽  
Gestational Age ◽  
Maternal Plasma ◽  
Clinical Risk Factors ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Clinical Risk ◽  
Prospective Longitudinal

The relationships and predictive abilities of perceived stress, selected clinical risk factors, and corticotropin-releasing hormone (CRH) levels in maternal plasma were investigated for their association with preterm labor (PTL), preterm birth, and gestational age at delivery. An exploratory, prospective, longitudinal research design was used to measure CRH 4 times over pregnancy, perceived stress at 24 and 32 weeks of pregnancy, clinical risk factors, and genitourinary infections in low-income women. Multiple regression analyses revealed that a model of measurement of perceived stress at 24 or 32 weeks, CRH at 24 or 32 weeks, and PTL (indicated by a diagnosis by the physicians on the medical record and greater than 5 contractions per hour on the fetal monitor) was predictive of as much as 0.23 to 0.27 of the variance in gestational age at birth. Entering ethnicity as a variable into a model did not improve the predictive value. An analysis of variance between Caucasian and Hispanic ethnic groups revealed differences in CRH levels. However, simple regression analysis of ethnicity as a predictor showed a weak r 2 with no significance for prediction. There was some evidence of an association of smoking with stress and both PTL and preterm birth. The measurement of stress combined with the measurement of CRH from maternal plasma may improve the prediction of which pregnant women are at risk for preterm birth. The measurement of CRH has potential as an early biological marker of preterm birth.

scholarly journals Regulation of the Human Corticotropin-Releasing-Hormone Gene Promoter Activity by Antidepressant Drugs in Neuro-2A and AtT-20 Cells

2004 ◽  
Vol 29 (4) ◽  
pp. 785-794 ◽  
Author(s):  
Bogusława Budziszewska ◽  
Lucylla Jaworska-Feil ◽  
Magdalena Tetich ◽  
Agnieszka Basta-Kaim ◽  
Marta Kubera ◽  
...  
Keyword(s):  
Promoter Activity ◽  
Antidepressant Drugs ◽  
Gene Promoter ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Vitamin D and corticotropin-releasing hormone in term and preterm birth: potential contributions to preterm labor and birth outcome

2017 ◽  
Vol 31 (21) ◽  
pp. 2911-2917 ◽  
Author(s):  
Sara A. Mohamed ◽  
Abdeljabar El Andaloussi ◽  
Ayman Al-Hendy ◽  
Ramkumar Menon ◽  
Faranak Behnia ◽  
...  
Keyword(s):  
Vitamin D ◽  
Preterm Birth ◽  
Preterm Labor ◽  
Birth Outcome ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

scholarly journals Antipsychotic Drugs Inhibit the Human Corticotropin-Releasing-Hormone Gene Promoter Activity in Neuro-2A Cells—an Involvement of Protein Kinases

2005 ◽  
Vol 31 (4) ◽  
pp. 853-865 ◽  
Author(s):  
Agnieszka Basta-Kaim ◽  
Bogusława Budziszewska ◽  
Lucylla Jaworska-Feil ◽  
Magdalena Tetich ◽  
Marta Kubera ◽  
...  
Keyword(s):  
Protein Kinases ◽  
Promoter Activity ◽  
Antipsychotic Drugs ◽  
Gene Promoter ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone
Sign in / Sign up

Export Citation Format

Share Document