Investigation of acquisition time for harmonization of image quality between PET/CT and PET/MRI systems: A phantom study

Optik ◽  
2021 ◽  
pp. 167594
Author(s):  
Seok Hwan Yoon ◽  
Chan Rok Park
Keyword(s):  
Image Quality ◽  
Phantom Study ◽  
Acquisition Time ◽  
Pet Ct

scholarly journals Evaluation of image quality at the detector’s edge of dedicated breast positron emission tomography

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Yoko Satoh ◽  
Utaroh Motosugi ◽  
Masamichi Imai ◽  
Yoshie Omiya ◽  
Hiroshi Onishi
Keyword(s):  
Image Quality ◽  
Chest Wall ◽  
Clinical Studies ◽  
Breast Imaging ◽  
Phantom Study ◽  
Breast Lesions ◽  
Clinical Images ◽  
Dedicated Breast Pet ◽  
Pet Ct ◽  
Significant Difference

Abstract Background Using phantoms and clinical studies in prone hanging breast imaging, we assessed the image quality of a commercially available dedicated breast PET (dbPET) at the detector’s edge, where mammary glands near the chest wall are located. These are compared to supine PET/CT breast images of the same clinical subjects. Methods A breast phantom with four spheres (16-, 10-, 7.5-, and 5-mm diameter) was filled with 18F-fluorodeoxyglucose solution (sphere-to-background activity concentration ratio, 8:1). The spheres occupied five different positions from the top edge to the centre of the detector and were scanned for 5 min in each position. Reconstructed images were visually evaluated, and the contrast-to-noise ratio (CNR), contrast recovery coefficient (CRC) for all spheres, and coefficient of variation of the background (CVB) were calculated. Subsequently, clinical images obtained with standard supine PET/CT and prone dbPET were retrospectively analysed. Tumour-to-background ratios (TBRs) between breast cancer near the chest wall (close to the detector’s edge; peripheral group) and at other locations (non-peripheral group) were compared. The TBR of each lesion was compared between dbPET and PET/CT. Results Closer to the detector’s edge, the CNR and CRC of all spheres decreased while the CVB increased in the phantom study. The disadvantages of this placement were visually confirmed. Regarding clinical images, TBR of dbPET was significantly higher than that of PET/CT in both the peripheral (12.38 ± 6.41 vs 6.73 ± 3.5, p = 0.0006) and non-peripheral (12.44 ± 5.94 vs 7.71 ± 7.1, p = 0.0183) groups. There was no significant difference in TBR of dbPET between the peripheral and non-peripheral groups. Conclusion The phantom study revealed poorer image quality at < 2-cm distance from the detector’s edge than at other more central parts. In clinical studies, however, the visibility of breast lesions with dbPET was the same regardless of the lesion position, and it was higher than that in PET/CT. dbPET has a great potential for detecting breast lesions near the chest wall if they are at least 2 cm from the edge of the FOV, even in young women with small breasts.

Acquisition Protocols to Optimize 68Ga-DOTA-NOC Position Emission Tomography/Computer Tomography Image Quality Based on Patient Body Mass Index and Injected Dose

2020 ◽  
Vol 10 (2) ◽  
pp. 508-514
Author(s):  
Lei Xu ◽  
Lei Lei Zhou ◽  
Zhenyu Zhao ◽  
Qingle Meng ◽  
Rui Yang ◽  
...  
Keyword(s):  
Image Quality ◽  
Dose Group ◽  
Group Versus ◽  
Normal Weight ◽  
Emission Tomography ◽  
Acquisition Time ◽  
Position Emission Tomography ◽  
Weight Group ◽  
Pet Ct ◽  
Overweight Group

Background: The choice of 68Ga-DOTA-1-Nal3-octreotide (68Ga-DOTA-NOC) injected dose and Position emission tomography/computer tomography (PET/CT) acquisition time is still a challenge for obtaining consistently high-quality PET image. Objective: To determine the optimal acquisition protocols based on patient body mass index (BMI) and the injected dose per kilogram for 68Ga-DOTA-NOC PET/CT imaging. Patients and Methods: This was a retrospective analysis of 51 patients (21 males and 30 females) who underwent clinical 68Ga-DOTANOC PET/CT imaging from November 2016 to March 2018 in Nanjing first hospital, the average BMI of these patients was 23.18 ± 3.45 kg/m2 with injected dose of 39.55–110.11 MBq. The study population was classified into groups based on Chinese standard BMI and injected dose. PET image quality and acquisition time were evaluated by coefficient of variance (CV) in the liver slice. Results: (1) The CV significantly increased with increasing weight and BMI (r = 0.647, 0.483, all P < 0.01), and significantly decreased with increasing injected dose per kilogram (r = 0 695, P < 0.01). (2) The CV differed significantly among 4 BMI-based groups, except for normal-weight group versus overweight group and overweight group versus obese group (P < 0.01), and the ratio of overweight group and obese group to normal weight group was approximately 1.1 and 1.2, respectively. Meanwhile, the CV had a significant statistical difference among 3 injected dose per kilogram groups (P < 0.01), and the ratio of that for low dose group and high dose group to moderate dose group was approximately 1.2 and 0.8. Conclusion: The findings showed a feasibility of obtaining consistently high-quality PET image at low injected dose and shorter acquisition time. Estimation of optimal acquisition time and injected dose using CV is valid in improving PET image quality, which can provide reference for the establishment and promotion of 68Ga-DOTA-NOC imaging protocols in China.

scholarly journals Examination of Optimal Window Size and Acquisition Time of Respiratory-gated PET Image: Phantom Study with a SiPM-based PET/CT Scanner

2020 ◽  
Vol 76 (8) ◽  
pp. 795-801
Author(s):  
Ryotaro Sato ◽  
Hayato Odagiri ◽  
Manami Ikawa ◽  
Hironobu Sasaki ◽  
Kentaro Takanami ◽  
...  
Keyword(s):  
Window Size ◽  
Phantom Study ◽  
Acquisition Time ◽  
Ct Scanner ◽  
Gated Pet ◽  
Pet Ct ◽  
Optimal Window

scholarly journals The Effect of Administered Activity on Patient Radiation dose and Image Quality in SPECT at Korle-Bu Teaching Hospital

2017 ◽  
pp. 204-211
Author(s):  
Issahaku Shirazu ◽  
Theophilus Sackey ◽  
Ernest Kojo Eduful
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Phantom Study ◽  
Acquisition Time ◽  
Image Study ◽  
Dynamic Studies ◽  
Increase With Increase ◽  
Medicine Physician ◽  
Patient Radiation Dose ◽  
Administered Activity

The study discussed two parameters these include; administered activity (patients dose) and image quality. The aim is to determine the relationship between administered activity with resultant patient radiation dose and the quality of images produced. This will help make appropriate recommendation to the technologist and the nuclear medicine physician to produce images that would answer clinical question and at the same time maintain a balance with patient's radiation dose and its prognostic consequences. The study include both quadrant bar phantom study and patient image study in the form of static and dynamic studies. To determine image quality both the quadrant bar phantom and the patients images were assess by using SNR. The quadrant bar phantom was imaged by placing it on flood field uniform phantom which contained the radionuclide. The flood field uniformity phantom was filled with water and then an injected activity, which varied between 5 to 45 mCi of Tc-99 m were added and mixed thoroughly by several shaking for about 5 minutes. Images of the quadrant bar phantom together with real patients’ images with varied injected activities were analyzed. The study shows that as the administered activity increases from 5 to 45mCi the image quality increases significantly, which is based on the increase in SNR. Where the image quality increases from 17.06 to 22.29 in LEAP collimator and 13.56 to 21.51 in LEHR collimator using patients’ static images. In addition, the image quality also increases from 18.26 to 20.44 in LEAP and 13.51 to 21.47 in LEHR collimator using quadrant bar phantom studies. Furthermore, in the of dynamic patients images, the SNR had minimal variation from 5.40 to 29.86 in LEAP and 7.11 to 21.99 in LEHR. Furthermore the reduction in administered activity increases the acquisition time from 7 to 20mins for LEAP collimator and 8 to 22 mins for LEHR collimator. In addition, with the phantom study, the acquisition time increases from 12 to 19 mins for LEAP and 13 to 15 mins for LEHR collimator. Dynamic studies varies slightly in acquisition time just approximately a min increase with increase in administered activity.

PET/CT BiographTM Sensation 16

2006 ◽  
Vol 45 (03) ◽  
pp. 126-133 ◽  
Author(s):  
Y. Bercier ◽  
M. Schwaiger ◽  
S. I. Ziegler ◽  
M.-J. Martínez
Keyword(s):  
Image Quality ◽  
Count Rate ◽  
Signal To Noise Ratio ◽  
Reconstruction Algorithm ◽  
Considerable Change ◽  
Acquisition Time ◽  
Average Increase ◽  
Scatter Fraction ◽  
Pet Ct ◽  
Before And After

SummaryAim: The new PET/CT Biograph Sensation 16 (BS16) tomographs have faster detector electronics which allow a reduced timing coincidence window and an increased lower energy threshold (from 350 to 400 keV). This paper evaluates the performance of the BS16 PET scanner before and after the Pico-3D electronics upgrade. Methods: Four NEMA NU 2–2001 protocols, (i) spatial resolution, (ii) scatter fraction, count losses and random measurement, (iii) sensitivity, and (iv) image quality, have been performed. Results: A considerable change in both PET count-rate performance and image quality is observed after electronics upgrade. The new scatter fraction obtained using Pico-3D electronics showed a 14% decrease compared to that obtained with the previous electronics. At the typical patient background activity (5.3 kBq/ml), the new scatter fraction was approximately 0.42. The noise equivalent count-rate (RNEC) performance was also improved. The value at which the RNEC curve peaked, increased from 3.7·104s-1 at 14 kBq/ml to 6.4·104s-1 at 21 kBq/ml (2R-NEC rate). Likewise, the peak true count-rate value increased from 1.9·105s-1 at 22 kBq/ml to 3.4·105s-1 at 33 kBq/ml. An average increase of 45% in contrast was observed for hot spheres when using AW-OSEM (4ix8s) as the reconstruction algorithm. For cold spheres, the average increase was 12%. Conclusion: The performance of the PET scanners in the BS16 tomographs is improved by the optimization of the signal processing. The narrower energy and timing coincidence windows lead to a considerable increase of signal- to-noise ratio. The existing combination of fast detectors and adapted electronics in the BS16 tomographs allow imaging protocols with reduced acquisition time, providing higher patient throughput.

The image quality, lesion detectability, and acquisition time of 18F-FDG total-body PET/CT in oncological patients

2020 ◽  
Vol 47 (11) ◽  
pp. 2507-2515 ◽  
Author(s):  
Yi-Qiu Zhang ◽  
Peng-Cheng Hu ◽  
Run-Ze Wu ◽  
Yu-Shen Gu ◽  
Shu-Guang Chen ◽  
...  
Keyword(s):  
Image Quality ◽  
Acquisition Time ◽  
Lesion Detectability ◽  
Oncological Patients ◽  
Pet Ct ◽  
18F Fdg ◽  
Total Body

scholarly journals Evaluation of image quality at the detector’s edge of dedicated breast positron emission tomography

2020 ◽  
Author(s):  
Yoko Satoh ◽  
Utaroh Motosugi ◽  
Masamichi Imai ◽  
Yoshie Omiya ◽  
Hiroshi Onishi
Keyword(s):  
Positron Emission Tomography ◽  
Image Quality ◽  
Chest Wall ◽  
Clinical Studies ◽  
Phantom Study ◽  
Emission Tomography ◽  
Breast Lesions ◽  
Clinical Images ◽  
Positron Emission ◽  
Pet Ct

Abstract Background: The dedicated breast positron emission tomography (dbPET) scanner (Elmamo, Shimadzu, Kyoto, Japan) has received approval from the Japanese Pharmaceutical Affairs Law and is commercially available in Japan. We assessed image quality of dbPET at the detector's edge, where the mammary glands near the chest wall are located in phantom and clinical studies.Methods: A breast phantom with four spheres (16, 10, 7.5, and 5 mm diameter) was filled with 18F-fluorodeoxyglucose solution (sphere-to-background ratio, 8:1). The spheres occupied five different positions from the top edge to the centre of the detector and were scanned for 5 min in each position. Reconstructed images were visually evaluated, and the contrast-to-noise ratio (CNR), contrast recovery coefficient (CRC) for the 5-mm sphere, and coefficient of variation of the background (CVB) were calculated. Subsequently, clinical images obtained with standard spine PET/CT and prone dbPET were retrospectively analysed. Tumour-to-background ratios (TBRs) between breast cancer near the chest wall (close to the detector’s edge; peripheral group) and at other locations (non-peripheral group) were compared. The TBR of each lesion was compared between dbPET and PET/computed tomography (CT).Results: Closer to the detector’s edge, the CNR and CRC decreased while the CVB increased in the phantom study. The disadvantages of this placement were visually confirmed. Regarding clinical images, TBR of dbPET was significantly higher than that of PET/CT in both the peripheral (12.38±6.41 vs 6.73±3.5, p=0.0006) and non-peripheral (12.44±5.94 vs 7.71±7.1, p=0.0183) groups. There was no significant difference in TBR of dbPET between the peripheral and non-peripheral groups (12.4±6.4 vs 12.4±5.9, p=0.8261).Conclusion: The phantom study revealed poorer image quality closer to the detector edge at a depth of <2 cm from the detector's edge than at other more central parts. In clinical studies, however, the visibility of breast lesions with dbPET was the same regardless of the lesion position, and it was higher than that in PET/CT. dbPET has a great potential for detecting breast lesions near the chest wall if they are at least 2 cm from the edge of the FOV, even in young women with small breasts.

scholarly journals Clinical evaluation of PET image quality as a function of acquisition time in a new TOF-PET/MR compared to TOF-PET/CT - initial results

2015 ◽  
Vol 2 (S1) ◽  
Author(s):  
Konstantinos Zeimpekis ◽  
Martin Huellner ◽  
Felipe De Galiza Barbosa ◽  
Edwin Ter Voert ◽  
Helen Davison ◽  
...  
Keyword(s):  
Image Quality ◽  
Clinical Evaluation ◽  
Acquisition Time ◽  
Pet Ct ◽  
Initial Results ◽  
Tof Pet

scholarly journals Image quality and detectability in Siemens Biograph PET/MRI and PET/CT systems—a phantom study

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Silje Kjærnes Øen ◽  
Lars Birger Aasheim ◽  
Live Eikenes ◽  
Anna Maria Karlberg
Keyword(s):  
Image Quality ◽  
Phantom Study ◽  
Siemens Biograph ◽  
Pet Ct

Dependence of image quality on acquisition time for the PET/CT Biograph mCT

2014 ◽  
Vol 24 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Flavia Molina-Duran ◽  
Dietmar Dinter ◽  
Frederic Schoenahl ◽  
Stefan O. Schoenberg ◽  
Gerhard Glatting
Keyword(s):  
Image Quality ◽  
Acquisition Time ◽  
Pet Ct
Sign in / Sign up

Export Citation Format

Share Document