MALDI-TOF mass spectrometry following short incubation on a solid medium is a valuable tool for rapid pathogen identification from positive blood cultures

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Alexander Hoffmann ◽  
Gabriele Geis ◽  
Sören Gatermann
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Author(s):  
Neele J. Froböse ◽  
Evgeny A. Idelevich ◽  
Frieder Schaumburg

When blood cultures are flagged as positive, they are incubated on solid media to produce enough biomass of the bacterium for identification and susceptibility testing. Rapid turnaround times for laboratory results could save lives, and we wanted to assess which solid medium is best to shorten the time to species identification using MALDI-TOF mass spectrometry.


2016 ◽  
Vol 26 (5) ◽  
pp. 69-73
Author(s):  
Lina Savickaitė ◽  
Jelena Kopeykinienė

Rapid identification of the infecting organism may aid in choosing appropriate antimicrobial therapy. We used MALDI-TOF mass spectrometry to identify bacteria directly from the positive blood culture samples (n=21). 85,71 percent of these results was identified using of MALDI-TOF mass spectrometry. Identification time of bacteria directly from the blood culture takes more than 1 hour for 27,8 percent results.


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Gisèle Cha Yapo-Kouadio ◽  
Anne-Cécile Normand ◽  
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Pierre Marty ◽  
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