scholarly journals Rapid Diagnosis of Mdr-Tb by Cbnaat Technique

2021 ◽  
Vol 39 ◽  
pp. S97
Author(s):  
Vishal Kulkarni ◽  
Shahriar Roushani
Keyword(s):  
Rapid Diagnosis ◽  
Mdr Tb

scholarly journals EBUS-TBNA in the rapid microbiological diagnosis of drug-resistant mediastinal tuberculous lymphadenopathy

2019 ◽  
Vol 5 (4) ◽  
pp. 00008-2019
Author(s):  
Prashant N. Chhajed ◽  
Preyas J. Vaidya ◽  
Neha P. Mandovra ◽  
Vinod B. Chavhan ◽  
Tejashree T. Lele ◽  
...  
Keyword(s):  
Needle Aspiration ◽  
Drug Susceptibility Testing ◽  
Rapid Diagnosis ◽  
Endobronchial Ultrasound ◽  
Rifampicin Resistance ◽  
Tuberculous Lymphadenitis ◽  
Drug Resistant ◽  
Transbronchial Needle Aspiration ◽  
Mdr Tb ◽  
Culture Positive

This study aimed to examine the use of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the rapid diagnosis of mediastinal tuberculous lymphadenitis and drug-resistant mediastinal tuberculous lymphadenitis.A diagnosis of TB was confirmed by a positive Xpert MTB/RIF test or Mycobacterium tuberculosis culture. Rifampicin-resistant TB (RR-TB) or multidrug-resistant TB (MDR-TB) was diagnosed upon the detection of rifampicin resistance by Xpert MTB/RIF or resistance to rifampicin and isoniazid by phenotypic drug susceptibility testing (DST).Xpert MTB/RIF was positive in 43 of 56 patients (77%) and TB culture was positive in 31 of 56 patients (55%). Of these 56 patients, 25 (45%) were Xpert MTB/RIF positive and TB culture negative, 13 (23%) were Xpert MTB/RIF negative and TB culture positive, and 18 (32%) were Xpert MTB/RIF positive and TB culture positive. 11 patients (20%) had drug-resistant TB: seven with RR/MDR-TB, one with pre-extensively drug-resistant (XDR) TB, two with XDR-TB and one with isoniazid mono-resistance.An Xpert MTB/RIF assay carried out on EBUS-TBNA specimens provides rapid diagnosis of TB. Xpert MTB/RIF testing appears to have additional and more rapid sensitivity compared with culture alone. Culture-based DST provides an additional exclusive yield and the full resistance profile in addition to or instead of rifampicin resistance.

MDR TB Outbreak in Hospital Nursery

1999 ◽  
Vol 20 (02) ◽  
pp. 146-147
Author(s):  
Gina Pugliese ◽  
Martin S. Favero
Keyword(s):  
Mdr Tb

Solid-phase immunoelectron microscopy for rapid diagnosis of enteroviruses

1984 ◽  
Vol 42 ◽  
pp. 226-227 ◽  
Author(s):  
K. Pegg-Feige ◽  
F. W. Doane
Keyword(s):  
Electron Microscopy ◽  
Cell Culture ◽  
Immunoelectron Microscopy ◽  
Detection Method ◽  
Solid Phase ◽  
Protein A ◽  
Plant Viruses ◽  
Rapid Diagnosis ◽  
Virus Diagnosis ◽  
Antiviral Antibody

Immunoelectron microscopy (IEM) applied to rapid virus diagnosis offers a more sensitive detection method than direct electron microscopy (DEM), and can also be used to serotype viruses. One of several IEM techniques is that introduced by Derrick in 1972, in which antiviral antibody is attached to the support film of an EM specimen grid. Originally developed for plant viruses, it has recently been applied to several animal viruses, especially rotaviruses. We have investigated the use of this solid phase IEM technique (SPIEM) in detecting and identifying enteroviruses (in the form of crude cell culture isolates), and have compared it with a modified “SPIEM-SPA” method in which grids are coated with protein A from Staphylococcus aureus prior to exposure to antiserum.

Tuberkulose in der Schweiz

2011 ◽  
Vol 68 (7) ◽  
pp. 365-368 ◽  
Author(s):  
Otto Brändli ◽  
Jean Pierre Zellweger
Keyword(s):  
Mdr Tb ◽  
Seltene Krankheit

Die Tuberkulose (TB) ist heute in der Schweiz zwar eine seltene Krankheit mit nur noch 2.8 Neuerkrankungen pro Jahr unter Schweizern. Sie kommt aber mit einem Anteil von 70 % in ausländischen Bevölkerungsgruppen noch relativ häufig vor. Nachdem die Gesamtzahlen während über 100 Jahren rückläufig waren, wurde zwischen 2007 und 2009 eine Zunahme von 478 auf 556 Fälle beobachtet, deren Ursache unklar bleibt. Das Auftreten von multiresistenten Formen (1.4 % MDR- TB) und die verzögerte Diagnosestellung erfordern weiterhin die volle Aufmerksamkeit der Ärzte und der Gesundheitsbehörden. Die Lungenligen engagieren sich bei der Umgebungsuntersuchung und Behandlung der TB und unterstützen die Ärzte mit dem „TB-Handbuch“ und einer Gratis-Hotline.

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