Fragmentation pathways of dianionic [Pt2(μ-P2O5H2)4+X,Y]2− (X,Y=H, K, Ag) species in an ion trap induced by collisions and UV photoexcitation

2016 ◽  
Vol 395 ◽  
pp. 7-19 ◽  
Author(s):  
Sebastian V. Kruppa ◽  
Yevgeniy Nosenko ◽  
Marc-Oliver Winghart ◽  
Simon P. Walg ◽  
Manfred M. Kappes ◽  
...  
Keyword(s):  
Ion Trap ◽  
Fragmentation Pathways

Fragmentation pathways of heroin-related alkaloids revealed by ion trap and quadrupole time-of-flight tandem mass spectrometry

2008 ◽  
Vol 22 (18) ◽  
pp. 2851-2862 ◽  
Author(s):  
Zhengxiang Zhang ◽  
Bo Yan ◽  
Kelin Liu ◽  
Tao Bo ◽  
Yiping Liao ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Ion Trap ◽  
Time Of Flight ◽  
Tandem Mass ◽  
Fragmentation Pathways

Fragmentation pathways of organoarsenical compounds by electrospray ion trap multiple mass spectrometry (MS6)

2001 ◽  
Vol 926 (1) ◽  
pp. 167-174 ◽  
Author(s):  
B.R Larsen ◽  
C Astorga-Llorens ◽  
M.H Florêncio ◽  
A.M Bettencourt
Keyword(s):  
Mass Spectrometry ◽  
Ion Trap ◽  
Fragmentation Pathways

Fragmentation studies of selected drugs utilized in palliative care

2018 ◽  
Vol 24 (6) ◽  
pp. 420-436 ◽  
Author(s):  
Tomasz Grześkowiak ◽  
Agnieszka Zgoła-Grześkowiak ◽  
Danuta Rusińska-Roszak ◽  
Iwona Zaporowska-Stachowiak ◽  
Magdalena Jeszka-Skowron
Keyword(s):  
Palliative Care ◽  
Mass Spectra ◽  
Ion Trap ◽  
Linear Ion Trap ◽  
Triple Quadrupole ◽  
Hyoscine Butylbromide ◽  
Fragmentation Pathways ◽  
Future Studies ◽  
Ion Trap Mass Spectrometer

The results of research on selected drugs used in palliative care are presented, including fentanyl, tramadol, metoclopramide, hyoscine butylbromide, midazolam, haloperidol, levomepromazine and clonazepam. Interpretation of their ESI mass spectra obtained by the use of a triple quadrupole linear ion trap mass spectrometer is given. As a result, fragmentation pathways described in the literature are complemented and presented with more details. On their basis, transitions for quantitative analysis are selected and chromatographic conditions for the determination of the palliative care drugs are proposed as well. These results enable future studies on palliative care drugs in elderly patients including both their quantitation in body fluids and easier identification of their metabolites.

scholarly journals Elucidation of the Mass Fragmentation Pathways of Tomatidine and β1-Hydroxytomatine using Orbitrap Mass Spectrometry

2015 ◽  
Vol 10 (4) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Giovanni Caprioli ◽  
Michael Cahill ◽  
Serena Logrippo ◽  
Kevin James
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectra ◽  
Ion Trap ◽  
Biological Effects ◽  
Biologically Active ◽  
Fragmentation Pathways ◽  
Multi Stage ◽  
Orbitrap Mass Spectrometry ◽  
Characteristic Fragmentation ◽  
Collisional Induced Dissociation

Tomatoes, members of the Solanaceae plant family, produce biologically active secondary metabolites, including glycoalkaloids, which may have both adverse and beneficial biological effects. Using the linear ion trap (LIT) mass spectrometry, multi-stage collision induced dissociation (CID) experiments (MSn) were performed to elucidate characteristic fragmentation pathways of the glycoalkaloid, tomatidine and of β1-hydroxytomatine. High resolution with high accuracy mass analysis using an Orbitrap fourier transform MS with higher-energy collisional induced dissociation (HCD) was used to produce mass spectra data across a wide spectral range for confirmation of proposed ion structures and formulae.

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