Association of lysyl oxidase (arginine 158 glycine) polymorphism with zinc-vitamin a supplementation in oral submucous fibrosis

2011 ◽  
Vol 40 (10) ◽  
pp. e28
Author(s):  
S. Mukherjee ◽  
A.K. Katarkar ◽  
J.G. Ray ◽  
K. Chaudhuri
Keyword(s):  
Vitamin A ◽  
Lysyl Oxidase ◽  
Oral Submucous Fibrosis ◽  
Vitamin A Supplementation ◽  
Submucous Fibrosis

scholarly journals Zinc and vitamin A can minimise the severity of oral submucous fibrosis

2010 ◽  
Vol 2010 (may11 1) ◽  
pp. bcr1020092348-bcr1020092348 ◽  
Author(s):  
R. Dhariwal ◽  
S. Mukherjee ◽  
S. P. (Mohanty) ◽  
A. Chakraborty ◽  
J. G. Ray ◽  
...  
Keyword(s):  
Vitamin A ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Genetic Susceptibility and Protein Expression of Extracellular Matrix Turnover-Related Genes in Oral Submucous Fibrosis

2020 ◽  
Vol 21 (21) ◽  
pp. 8104
Author(s):  
Ru-Hsiu Cheng ◽  
Yi-Ping Wang ◽  
Julia Yu-Fong Chang ◽  
Yu-Hwa Pan ◽  
Mei-Chi Chang ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Oral Cancer ◽  
Genetic Susceptibility ◽  
Molecular Mechanisms ◽  
Lysyl Oxidase ◽  
Oral Submucous Fibrosis ◽  
Tissue Inhibitors Of Metalloproteinases ◽  
Contributing Factors ◽  
Plasminogen Activator Inhibitor 1 ◽  
Submucous Fibrosis

Betel quid (BQ) chewing increased the risk of oral cancer and oral submucous fibrosis (OSMF), an oral premalignant disorder (OPMD) with malignant transformation potential. BQ components such as areca nut (AN), trauma by coarse AN fiber, catechin, copper, alkaloids, stimulated reactive oxygen species (ROS), inflammation and cytotoxicity are suggested to be the contributing factors. They may induce tissue inflammation, proliferation of fibroblasts and collagen deposition, myofibroblast differentiation and contraction, collagen cross-links and inhibit collagen phagocytosis, finally leading to the development of OSMF and oral cancer. These events are mediated by BQ components-induced changes of extracellular matrix (ECM) turnover via regulation of TGF-β1, plasminogen activator inhibitor-1 (PAI-1), cystatin, lysyl oxidase (LOX) and tissue inhibitors of metalloproteinases (TIMPs) and metalloproteinases (MMPs). Genetic susceptibility is also involved in these disease processes. Further understanding the molecular mechanisms of BQ-induced OSMF and oral cancer can be helpful for future disease prevention and treatment.

The upregulation of lysyl oxidase in oral submucous fibrosis and squamous cell carcinoma

2007 ◽  
Vol 28 (6) ◽  
pp. 246-251 ◽  
Author(s):  
C. Trivedy ◽  
K. A. A. S. Warnakulasuriya ◽  
V. K. Hazarey ◽  
M. Tavassoli ◽  
P. Sommer ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lysyl Oxidase ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

Comment on Mukherjee S et al. “Zinc and Vitamin A as a low cost management of oral submucous fibrosis”

Oral Oncology ◽  
2012 ◽  
Vol 48 (11) ◽  
pp. e46 ◽  
Author(s):  
Revant H. Chole ◽  
Shailesh M. Gondivkar ◽  
Amol R. Gadbail ◽  
Swati V. Balsaraf
Keyword(s):  
Vitamin A ◽  
Cost Management ◽  
Low Cost ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

Association between lysyl oxidase polymorphisms and oral submucous fibrosis in older male areca chewers

2008 ◽  
Vol 38 (1) ◽  
pp. 109-113 ◽  
Author(s):  
Tzong-Ming Shieh ◽  
His-Feng Tu ◽  
Ti-Hsuan Ku ◽  
Shu-Shin Chang ◽  
Kuo-Wei Chang ◽  
...  
Keyword(s):  
Lysyl Oxidase ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Effect of Lysyl Oxidase G473 A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis

2021 ◽  
Vol 22 (8) ◽  
pp. 2493-2499
Author(s):  
Sanjit Mukherjee ◽  
Atul Katarkar ◽  
Richa Dhariwal ◽  
Sweta Mohanty ◽  
Basudev Mahato ◽  
...  
Keyword(s):  
Lysyl Oxidase ◽  
Oral Submucous Fibrosis ◽  
Collagen Expression ◽  
Soluble Collagen ◽  
Submucous Fibrosis
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