An estimation of serum malondialdehyde, superoxide dismutase and vitamin A in oral submucous fibrosis and its clinicopathologic correlation

2007 ◽  
Vol 11 (1) ◽  
pp. 23 ◽  
Author(s):  
JV Tupkari ◽  
SR Barpande ◽  
SuryakantB Metkari
Keyword(s):  
Superoxide Dismutase ◽  
Vitamin A ◽  
Oral Submucous Fibrosis ◽  
Clinicopathologic Correlation ◽  
Submucous Fibrosis

scholarly journals Zinc and vitamin A can minimise the severity of oral submucous fibrosis

2010 ◽  
Vol 2010 (may11 1) ◽  
pp. bcr1020092348-bcr1020092348 ◽  
Author(s):  
R. Dhariwal ◽  
S. Mukherjee ◽  
S. P. (Mohanty) ◽  
A. Chakraborty ◽  
J. G. Ray ◽  
...  
Keyword(s):  
Vitamin A ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Oral submucous fibrosis: A quantitative assessment of serum malondialdehyde, superoxide dismutase and correlation with clinical staging

2017 ◽  
Vol 21 (1) ◽  
pp. 41
Author(s):  
Ratnakar Bale ◽  
KiranKumar Kattappagari ◽  
Desai Vidya ◽  
Sivapradobh Vuddandi ◽  
Charani Gummalla ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Quantitative Assessment ◽  
Oral Submucous Fibrosis ◽  
Clinical Staging ◽  
Submucous Fibrosis

Comment on Mukherjee S et al. “Zinc and Vitamin A as a low cost management of oral submucous fibrosis”

Oral Oncology ◽  
2012 ◽  
Vol 48 (11) ◽  
pp. e46 ◽  
Author(s):  
Revant H. Chole ◽  
Shailesh M. Gondivkar ◽  
Amol R. Gadbail ◽  
Swati V. Balsaraf
Keyword(s):  
Vitamin A ◽  
Cost Management ◽  
Low Cost ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Superoxide dismutase and glutathione peroxidase in oral submucous fibrosis, oral leukoplakia, and oral cancer: A comparative study

2012 ◽  
Vol 4 (2) ◽  
pp. 114 ◽  
Author(s):  
Yadavalli Guruprasad ◽  
RaghavendraMahadev Naik ◽  
Anuradha Pai ◽  
D Sujatha ◽  
KS Ganapathy ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Oral Cancer ◽  
Glutathione Peroxidase ◽  
Comparative Study ◽  
Oral Submucous Fibrosis ◽  
Oral Leukoplakia ◽  
Submucous Fibrosis

scholarly journals Evaluation of Salivary Superoxide Dismutase Levels in Oral Submucous Fibrosis – A Cross Sectional Study

2021 ◽  
Vol 3 (3) ◽  
pp. 34-37
Author(s):  
Kavita Nagar ◽  
G.P. Sujatha ◽  
Ashok Lingappa
Keyword(s):  
Superoxide Dismutase ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Control Group ◽  
Study Group ◽  
Cross Sectional ◽  
Potential Biomarker ◽  
Increased Risk ◽  
Potentially Malignant ◽  
Submucous Fibrosis

Background: Oral Submucous Fibrosis (OSMF) is a potentially malignant disorder with areca nut being the main etiological agent. Increased risk of malignant potential of OSMF necessitates the early diagnosis of the condition. Superoxide dismutase (SOD) scavenges oxygenated free radicals and can be used as a potential biomarker for oral cancer detection. Objectives: The present study was conducted to estimate and compare salivary SOD levels in patients with OSMF and healthy controls and to compare its levels in different clinical and functional stages of OSMF. Methodology: The study group (Group 1) included 30 patients of OSMF, and the control group (Group 2) was formed by age and sex-matched healthy individuals. Salivary SOD levels were determined by Nitro Blue Tetrazolium (NBT) chloride method. The levels of salivary SOD were compared between the two groups and the data thus obtained was subjected to statistical analysis using independent sample t-test and one way Analysis of variance (ANOVA) test. Results: The mean salivary SOD in the study group was 0.583 IU/mL and 0.864 IU/mL in control group and the difference was found to be statistically significant. Thus, the patients with OSMF had significantly lower levels of salivary SOD compared to the controls. Conclusion: The decrease in the salivary SOD levels in patients with OSMF suggests the role of oxidative stress in the pathogenesis of OSMF and initiation and progression of carcinogenesis. Thus, it can be used as a prognostic marker for early detection of carcinoma in patients with OSMF and thereby, improving the quality of life patients.

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