Anatomical restrictions in the surgical excision of scalp squamous cell carcinomas: does this affect local recurrence and regional nodal metastases?

2014 ◽  
Vol 43 (2) ◽  
pp. 142-146 ◽  
Author(s):  
G. Jenkins ◽  
A.B. Smith ◽  
A.N. Kanatas ◽  
D.R. Houghton ◽  
M.R. Telfer
Keyword(s):  
Local Recurrence ◽  
Squamous Cell ◽  
Surgical Excision ◽  
Squamous Cell Carcinomas ◽  
Nodal Metastases

Carcinoma of the Nasal Septum: Experience with 85 Cases

1982 ◽  
Vol 90 (1) ◽  
pp. 90-94 ◽  
Author(s):  
Charles W. Beatty ◽  
Bruce W. Pearson ◽  
Eugene B. Kern
Keyword(s):  
Squamous Cell Carcinoma ◽  
Malignant Melanoma ◽  
Squamous Cell ◽  
Nasal Septum ◽  
Surgical Excision ◽  
Squamous Cell Carcinomas ◽  
Cell Type ◽  
Predominant Cell Type ◽  
Choice Of Treatment ◽  
Initial Choice

A review of 85 Mayo Clinic patients with carcinoma of the nasal septum revealed squamous cell carcinoma (58 patients) to be the predominant cell type, with adenocarcinoma (12 patients) and malignant melanoma (7 patients) being next in frequency. Twenty-five (29%) of the 85 patients had metastatic disease. Twenty percent (17) of the patients had another malignancy at some time during their lives. The study suggests that tobacco smoking may have a role in the etiology of squamous cell carcinomas of the nasal septum. In most patients, wide surgical excision was the initial choice of treatment.

Bilateral Rostral Maxillectomy and Nasal Planectomy for Large Rostral Maxillofacial Neoplasms in Six Dogs and One Cat

2004 ◽  
Vol 40 (2) ◽  
pp. 137-146 ◽  
Author(s):  
B. Duncan X. Lascelles ◽  
Ralph A. Henderson ◽  
Bernard Seguin ◽  
Julius M. Liptak ◽  
Stephen J. Withrow
Keyword(s):  
Postoperative Complications ◽  
Local Recurrence ◽  
Squamous Cell ◽  
Intraoperative Complications ◽  
Squamous Cell Carcinomas ◽  
Complete Excision ◽  
Poorly Differentiated

This paper describes in detail an aggressive rostral maxillectomy procedure in one cat and six dogs, and the postoperative complications and outcomes are reported. The surgeries were performed to attempt complete excision of large and extensive rostral maxillary fibrosarcomas (n=4), squamous cell carcinomas (n=2), or poorly differentiated mesenchymal neoplasia (n=1). The surgeries involved transection of the maxilla at the level of premolar (PM)1 and PM2 in a cat and two dogs, and between PM2 and PM3 in four dogs. There were no intraoperative complications. Complete margins of resection were obtained in all cases. The postoperative appearance was acceptable to owners. Local recurrence was only observed in one dog (10 months after surgery) during a follow-up period of 11 to 66 months (median, 21.5 months).

Cyclin D1 protein expression is related to clinical progression in laryngeal squamous cell carcinomas

1997 ◽  
Vol 111 (7) ◽  
pp. 622-626 ◽  
Author(s):  
Pasquale Capaccio ◽  
Giancarlo Pruneri ◽  
Nadia Carboni ◽  
Angelo Virgilio Pagliari ◽  
Roberto Buffa ◽  
...  
Keyword(s):  
Protein Expression ◽  
Cyclin D1 ◽  
Squamous Cell ◽  
D1 Protein ◽  
Squamous Cell Carcinomas ◽  
Low Grade ◽  
Nodal Metastases ◽  
Tumour Extension ◽  
Cyclin D1 Protein ◽  
Cyclin Dl

AbstractThe expression of cyclin D1 gene was investigated in 74 laryngeal squamous cell carcinomas (LSCCs) in order to determine its clinical and prognostic value. Overexpression of cyclin Dl was detected immunohistochemically using DCS6 monoclonal antibody on formalin-fixed, paraffin-embedded tissue sections. Cyclin D1 expression was detected in 22 of the 74 cases investigated (30 per cent), thirteen of which presented nodal metastases (59 per cent); of the patients without any detectable cyclin D1 protein expression, six presented nodal metastases (12 per cent). Cyclin D1 protein expression was found in five per cent of the specimens of normal mucosa, eight per cent of thosewith low-grade dysplasia and 20 per cent of those with high-grade dysplasia. A statistically significant association was found between cyclin D1 expression and the supraglottic site (p<0.05), tumour extension (p<0.001), the presence of lymph node metastases (p<0.001), and advanced clinical stage (p<0.001). Cyclin D2 expression analysis is an important tool in the selection of LSCC patients with an aggressive clinical course.

Molecular Alterations in Nodal Metastases and its Primary Tumors in Squamous Cell Carcinomas of the Larynx

2008 ◽  
Vol 59 (3) ◽  
pp. 114-119 ◽  
Author(s):  
Juan Pablo Rodrigo ◽  
Rubén Cabanillas ◽  
María Dolores Chiara ◽  
Juana García Pedrero ◽  
Manuel Florentino Fresno ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Nodal Metastases ◽  
Primary Tumors ◽  
Molecular Alterations

Malignant Tumours of the External Ear

1993 ◽  
Vol 1 (4) ◽  
pp. 177-183
Author(s):  
Cengiz H Karsli ◽  
Oleh M Antonyshyn ◽  
Christopher R Forrest ◽  
Dalai Assaad ◽  
Ida Ackerman
Keyword(s):  
Squamous Cell ◽  
Frozen Section ◽  
Single Case ◽  
Retrospective Chart Review ◽  
External Auditory Meatus ◽  
Surgical Excision ◽  
Squamous Cell Carcinomas ◽  
External Ear ◽  
Malignant Tumours ◽  
Regional Cancer Centre

CH Karsli, OM Antonyshyn, CR Forrest, D Assaad, I Ackerman. Malignant tumours of the external ear. Can J Plast Surg 1994;1(4): 177-183. This study employs a retrospective chart review to describe the demographic features, clinical presentation and treatment of malignant tumours of the external ear. This series includes 129 tumours of the external ear in as many consecutive patients presenting to the Toronto Bayview Regional Cancer Centre between January 1986 and December 1991. Sixty-seven per cent of those tumours were basal cell carcinomas, 32% were squamous cell carcinomas, and a single case of Kaposi's sarcoma was encountered. The majority of patients was male and the mean age was 70.1 years. The helical rim was the most common site of involvement, followed by the postauricular, conchal and antihelical regions. Small tumours were located in the visually obvious areas of the ear, namely the helix and lobule, whereas larger tumours were found in the deeper central portions such as the concha and external auditory meatus. Twelve per cent of squamous cell carcinomas were metastatic at the time of treatment. Treatment methods included electrodesiccation and curettage, surgical excision with or without frozen sections, radiotherapy or combination therapy. Surgical excision, with frozen section control in carefully selected cases, remains the treatment of choice for the majority of external ear tumours. Various methods of reconstruction of the resulting defects are described.

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