Development and evaluation of a tampering resistant transdermal fentanyl patch

2015 ◽  
Vol 488 (1-2) ◽  
pp. 102-107 ◽  
Author(s):  
Bing Cai ◽  
Håkan Engqvist ◽  
Susanne Bredenberg
1996 ◽  
Vol 32 (1) ◽  
pp. 19-24 ◽  
Author(s):  
M Scherk-Nixon

A transdermal therapeutic system (TTS) has been developed for the continuous delivery of fentanyl citrate to provide ongoing analgesia in human patients with chronic pain. Several researchers believe that fentanyl transdermal patches have a place in postoperative pain control. The purpose of this study was to determine whether transdermal technology is an effective way of administering fentanyl to feline patients. Fentanyl patches were applied to the skin of six cats, and blood samples for fentanyl analysis were collected over 104 hours. This study establishes that the transdermal patch technology is an effective, long-lasting, cost-effective, noninvasive, and well-tolerated mode of deliverying fentanyl to cats.


1998 ◽  
Vol 27 (2) ◽  
pp. 159-166 ◽  
Author(s):  
CHRISTINE M. EGGER ◽  
TANYA DUKE ◽  
JOY ARCHER ◽  
PETER H. CRIBB

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Lindsey N. Haut ◽  
Rupa Radhakrishnan ◽  
Riad Lutfi ◽  
Louise W. Kao ◽  
Laurie L. Ackerman

The opioid epidemic continues to have devastating consequences for children and families across the United States with rising prevalence of opioid use and abuse. Given the ease of access to these medications, accidental ingestion and overdose by children are becoming increasingly more common. The recognition of opioid-induced neurotoxicity and the associated life-threatening complication of acute cerebellar cytotoxic edema are crucial, as are the high morbidity and mortality without timely intervention. We discuss an infant with acute cytotoxic cerebellar edema following mucosal exposure to a transdermal fentanyl patch.


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