Brain targeted delivery of carmustine using solid lipid nanoparticles modified with tamoxifen and lactoferrin for antitumor proliferation

2016 ◽  
Vol 499 (1-2) ◽  
pp. 10-19 ◽  
Author(s):  
Yung-Chih Kuo ◽  
Shih-Jue Cheng
2014 ◽  
Vol 114 ◽  
pp. 407-415 ◽  
Author(s):  
Tuan Hiep Tran ◽  
Ju Yeon Choi ◽  
Thiruganesh Ramasamy ◽  
Duy Hieu Truong ◽  
Chien Ngoc Nguyen ◽  
...  

2015 ◽  
Vol 12 (4) ◽  
pp. 1230-1241 ◽  
Author(s):  
Jin-Ho Kim ◽  
Youngwook Kim ◽  
Ki Hyun Bae ◽  
Tae Gwan Park ◽  
Jung Hee Lee ◽  
...  

2020 ◽  
Vol 12 (4) ◽  
pp. 380
Author(s):  
JohnSushma Nannepaga ◽  
Swathi Ganna ◽  
RajasekharaReddy Gutturu ◽  
Rajesh Megala ◽  
Rasajna Nadella ◽  
...  

Drug Delivery ◽  
2018 ◽  
Vol 25 (1) ◽  
pp. 716-722 ◽  
Author(s):  
Meiling Zhou ◽  
Jierong Hou ◽  
Zhirong Zhong ◽  
Na Hao ◽  
Yan Lin ◽  
...  

2020 ◽  
pp. 72-80
Author(s):  
Varlamova ◽  
Arkhipov ◽  
Khalikov

A review of new directions in obtaining and manufacturing of innovative antiparasitic drugs is presented. The immobilization of antiparasitic drugs on or in nanoparticles to increase the efficacy and reduce side effects of drugs by improving the parameters of adsorption, bioavailability, slow release and intracellular permeability has been the most widespread direction in recent decades. Currently, such carriers as liposomes, polymer nanoparticles, solid lipid nanoparticles, nanosuspensions, nanocrystals, etc. are used as drug delivery systems for antiparasitic drugs. Studies conducted in our country have confirmed the efficacy of mechanochemical technology for producing solid dispersions of certain anthelmintic drugs (niclosamide, albendazole, fenbendazole, triclabendazole, praziquantel etc.) with excipients (arabinogalactan, polyvinylpyrrolidone, glycyrrhizic acid, etc.). On the example of solid lipid nanoparticles (SLN), the possibility and prospects of their further study and use as potential means of targeted delivery of antiparasitic drugs are shown, various manufacturing technologies are indicated, including homogenization methods, the use of supercritical fluids, the method of dry spray, evaporation, ultrasonic treatment, double emulsions, etc.


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