Maturation of auditory function related to hearing threshold estimations using the auditory brainstem response during infancy

2011 ◽  
Vol 75 (2) ◽  
pp. 163-170 ◽  
Author(s):  
Andre M. Marcoux
Keyword(s):  
Auditory Brainstem Response ◽  
Hearing Threshold ◽  
Auditory Brainstem ◽  
Auditory Function ◽  
Brainstem Response

scholarly journals A validation study of auditory function in an aminoglycoside-furosemide ototoxicity mouse model: Auditory brainstem response and distortion product otoacoustic emissions

2021 ◽  
Vol 5 ◽  
pp. 239784732110168
Author(s):  
Yeji Ahn ◽  
Jin Sil Choi ◽  
Dae Hyun Kim ◽  
Temuulen Batsaikhan ◽  
Young Joon Seo
Keyword(s):  
Hearing Loss ◽  
Mouse Model ◽  
Auditory Brainstem Response ◽  
Hearing Threshold ◽  
Otoacoustic Emission ◽  
Auditory Brainstem ◽  
Auditory Function ◽  
Brainstem Response ◽  
Ototoxic Drugs ◽  
Ototoxic Drug

Sensorineural hearing loss due to ototoxic drugs remains as a conflict as the treatment option with aminoglycosides. Ototoxic mouse model was produced with the administration of ototoxic drugs aminoglycoside kanamycin and loop-diuretic furosemide, thus validation of auditory function of the mouse model is needed to determine the efficacy of the drugs. Kanamycin sulfate 550 mg/kg (VWR life sciences, PA, USA) and furosemide 130 mg/kg (Lasix, Handok, Korea) were administered through subcutaneous and intraperitoneal injection respectively. Auditory brainstem response and distortion otoacoustic emission tests were performed on days 3,5,7,10,14 post administration of the ototoxic drug. Thresholds in response to the stimulus given in the auditory brainstem recordings and distortion otoacoustic emission tests were obtained. The hearing threshold shift to high stimulus intensity was observed post administration of the ototoxic drug. Latency of the ABR peak waves were recorded and analyzed, latency delay was observed as hearing threshold increases. These findings will further support in the application of this animal model in various studies regarding ototoxic hearing loss.

Auditory steady state response in auditory neuropathy

2010 ◽  
Vol 124 (9) ◽  
pp. 950-956 ◽  
Author(s):  
A A Emara ◽  
T A Gabr
Keyword(s):  
Steady State ◽  
Auditory Brainstem Response ◽  
Otoacoustic Emissions ◽  
Hearing Threshold ◽  
Auditory Brainstem ◽  
Auditory Neuropathy ◽  
Steady State Response ◽  
State Response ◽  
Auditory Steady State Response ◽  
Brainstem Response

AbstractReview:Auditory neuropathy is a disorder characterised by preservation of outer hair cell function, with normal otoacoustic emissions and/or cochlear microphonics, but an absent or distorted auditory brainstem response.Purpose:This study aimed to objectively assess hearing thresholds in patients with auditory neuropathy, using the auditory steady state response.Materials and methods:Thirteen patients with auditory neuropathy and 15 normal hearing subjects were examined. Audiological evaluation included basic audiological tests, otoacoustic emissions, auditory brainstem response and auditory steady state response.Results:In the auditory neuropathy patients, the auditory brainstem response was absent in 11 patients, while the auditory steady state response was absent in only three.Conclusion:The auditory steady state response may serve as a valuable objective measure for assessing the hearing threshold across different frequencies in patients with auditory neuropathy. We recommend that auditory steady state response be used to complete the evaluation of patients with auditory neuropathy.

The Use of Artificial Neural Networks for Objective Determination of Hearing Threshold Using the Auditory Brainstem Response

2011 ◽  
pp. 195-216
Author(s):  
Robert T. Davey ◽  
Paul J. McCullagh ◽  
H. Gerry McAllister ◽  
H. Glen Houston
Keyword(s):  
Auditory Brainstem Response ◽  
Classification Accuracy ◽  
Hearing Threshold ◽  
Auditory Brainstem ◽  
Time Frequency ◽  
Response Data ◽  
Brainstem Response ◽  
Stage Process ◽  
High Level ◽  
Age Range

We have analyzed high and low level auditory brainstem response data (550 waveforms over a large age range; 126 were repeated sessions used in correlation analysis), by extracting time, frequency, and phase features and using these as inputs to ANN and decision tree classifiers. A two stage process is used. For responses with a high poststimulus to prestimulus power ratio indicative of high level responses, a classification accuracy of98% has been achieved. These responses are easily classified by the human expert. For lower level responses appropriate to hearing threshold, additional features from time, frequency, and phase have been used for classification, providing accuracies between 65% and 82%. These used a dataset with repeated recordings so that correlation could be employed. To increase classification accuracy, it may be necessary to combine the relevant features in a hybrid model.

Hearing threshold in preterm and term infantsby auditory brainstem response

1985 ◽  
Vol 107 (4) ◽  
pp. 593-599 ◽  
Author(s):  
Sana Lary ◽  
George Briassoulis ◽  
Linda de Vries ◽  
Lilly M.S. Dubowitz ◽  
V.ictor. Dubowitz
Keyword(s):  
Auditory Brainstem Response ◽  
Hearing Threshold ◽  
Auditory Brainstem ◽  
Brainstem Response

The Impact of Clinical History on the Threshold Estimation of Auditory Brainstem Response Results for Infants

2017 ◽  
Vol 60 (3) ◽  
pp. 725-731 ◽  
Author(s):  
Maha Zaitoun ◽  
Steven Cumming ◽  
Alison Purcell ◽  
Katie O'Brien
Keyword(s):  
Auditory Brainstem Response ◽  
Hearing Threshold ◽  
Clinical Information ◽  
Clinical History ◽  
Auditory Brainstem ◽  
True Negative ◽  
History Information ◽  
Brainstem Response ◽  
The Difference ◽  
The Impact

Purpose This study assesses the impact of patient clinical history on audiologists' performance when interpreting auditory brainstem response (ABR) results. Method Fourteen audiologists' accuracy in estimating hearing threshold for 16 infants through interpretation of ABR traces was compared on 2 occasions at least 5 months apart. On the 1st occasion, ABR traces were presented to the audiologists with no clinical information except for the age of the child. On the 2nd occasion, audiologists were given a full clinical history for the ABR cases. Results The addition of clinical history information had no statistically significant impact on sensitivity, specificity, or accuracy of diagnosis. Although the mean numbers of true-negative and true-positive diagnoses were higher when audiologists were given clinical information, the difference was again not statistically significant. Conclusion This study suggests that if there are circumstances in which case material is incomplete or unavailable, audiologists have no cause for concern regarding the accuracy of their interpretation of ABR traces. In a clinical manner, this may help audiologists with large caseloads or audiologists who need to provide a diagnosis of hearing loss in a short time by allowing them to focus on conducting ABR without the need for case history information.

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