Total Body Irradiation Compared With BEAM: Long-Term Outcomes of Peripheral Blood Autologous Stem Cell Transplantation for Non-Hodgkin's Lymphoma

2010 ◽  
Vol 78 (2) ◽  
pp. 513-520 ◽  
Author(s):  
Hong-Wei Liu ◽  
Matthew D. Seftel ◽  
Morel Rubinger ◽  
David Szwajcer ◽  
Alain Demers ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autologous Stem Cell Transplantation ◽  
Total Body Irradiation ◽  
Peripheral Blood ◽  
Hodgkin's Lymphoma ◽  
Long Term Outcomes ◽  
Total Body

scholarly journals The Burden of Survivorship on Hematological Patients—Long-Term Analysis of Toxicities after Total Body Irradiation and Allogeneic Stem Cell Transplantation

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5640
Author(s):  
Michael Oertel ◽  
Jonas Martel ◽  
Jan-Henrik Mikesch ◽  
Sergiu Scobioala ◽  
Christian Reicherts ◽  
...  
Keyword(s):  
Stem Cell ◽  
Side Effects ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Allogeneic Stem Cell Transplantation ◽  
Total Body Irradiation ◽  
Whole Body ◽  
Total Body

Total body irradiation is an effective conditioning modality before autologous or allogeneic stem cell transplantation. With the whole body being the radiation target volume, a diverse spectrum of toxicities has been reported. This fact prompted us to investigate the long-term sequelae of this treatment concept in a large patient cohort. Overall, 322 patients with acute leukemia or myelodysplastic syndrome with a minimum follow-up of one year were included (the median follow-up in this study was 68 months). Pulmonary, cardiac, ocular, neurological and renal toxicities were observed in 23.9%, 14.0%, 23.6%, 23.9% and 20.2% of all patients, respectively. The majority of these side effects were grades 1 and 2 (64.9–89.2% of all toxicities in the respective categories). The use of 12 Gray total body irradiation resulted in a significant increase in ocular toxicities (p = 0.013) and severe mucositis (p < 0.001). Renal toxicities were influenced by the age at transplantation (relative risk: 1.06, p < 0.001) and disease entity. In summary, total body irradiation triggers a multifaceted, but manageable, toxicity profile. Except for ocular toxicities and mucositis, a 12 Gray regimen did not lead to an increase in long-term side effects.

scholarly journals Long-term outcomes in children with high-risk neuroblastoma treated with autologous stem cell transplantation

2007 ◽  
Vol 40 (8) ◽  
pp. 741-746 ◽  
Author(s):  
T N Trahair ◽  
M R Vowels ◽  
K Johnston ◽  
R J Cohn ◽  
S J Russell ◽  
...  
Keyword(s):  
Stem Cell ◽  
High Risk ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autologous Stem Cell Transplantation ◽  
Long Term Outcomes

scholarly journals Correction: Long-term outcomes of the GPOH NB97 trial for children with high-risk neuroblastoma comparing high-dose chemotherapy with autologous stem cell transplantation and oral chemotherapy as consolidation

2019 ◽  
Vol 121 (10) ◽  
pp. 894-895 ◽  
Author(s):  
Frank Berthold ◽  
Angela Ernst ◽  
Barbara Hero ◽  
Thomas Klingebiel ◽  
Bernhard Kremens ◽  
...  
Keyword(s):  
Stem Cell ◽  
High Risk ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autologous Stem Cell Transplantation ◽  
High Dose Chemotherapy ◽  
Oral Chemotherapy ◽  
High Dose ◽  
Long Term Outcomes

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Efficacy and Long-Term Outcomes of Autologous Stem Cell Transplantation in POEMS Syndrome: A Nationwide Survey in Japan

2018 ◽  
Vol 24 (6) ◽  
pp. 1180-1186 ◽  
Author(s):  
Chika Kawajiri-Manako ◽  
Emiko Sakaida ◽  
Chikako Ohwada ◽  
Toshihiro Miyamoto ◽  
Taichi Azuma ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autologous Stem Cell Transplantation ◽  
Nationwide Survey ◽  
Poems Syndrome ◽  
Long Term Outcomes
Sign in / Sign up

Export Citation Format

Share Document