Hearing Loss and Tumor Control following Fractionated Stereotactic Radiation Therapy (FSRT) for Vestibular Schwannoma (VS): The Johns Hopkins Hospital (JHH) Experience

2010 ◽  
Vol 78 (3) ◽  
pp. S9 ◽  
Author(s):  
H. Qiu ◽  
K.J. Redmond ◽  
S. Batra ◽  
E. Ford ◽  
L.R. Kleinberg ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Radiation Therapy ◽  
Vestibular Schwannoma ◽  
Johns Hopkins Hospital ◽  
Tumor Control ◽  
Stereotactic Radiation Therapy ◽  
Stereotactic Radiation ◽  
Fractionated Stereotactic Radiation Therapy

scholarly journals Single Dose versus Fractionated Stereotactic Radiotherapy for Meningiomas

2002 ◽  
Vol 29 (3) ◽  
pp. 240-248 ◽  
Author(s):  
Simon S. Lo ◽  
Kwan H. Cho ◽  
Walter A. Hall ◽  
Ronald J. Kossow ◽  
Wilson L. Hernandez ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Late Complications ◽  
Treatment Modalities ◽  
Tumor Control ◽  
Stereotactic Radiation Therapy ◽  
Tumor Control Probability ◽  
Stereotactic Radiation ◽  
Conventional Fractionation ◽  
Fractionated Stereotactic Radiation Therapy

Objective:To evaluate the safety and efficacy of stereotactic radiosurgery (SRS) compared to fractionated stereotactic radiation therapy (FSRT) for meningiomas treated over a seven year period.Methods and materials:Of the 53 patients (15 male and 38 female) with 63 meningiomas, 35 were treated with SRS and the 18 patients with tumors adjacent to critical structures or with large tumors were treated with FSRT. The median doses for the SRS and the FSRT groups were 1400 cGy (500- 4500 cGy) and 5400 cGy (4000-6000 cGy) respectively. Median target volumes for SRS and FSRT were 6.8 ml and 8.8 ml respectively. The median follow-up for the SRS and FSRT groups were 38 months (4.1-97 months) and 30.5 months (6.0-63 months) respectively.Results:The five-year tumor control probability (TC) for benign versus atypical meningiomas were 92.7% vs. 31% (P=.006). The three-year TC were 92.7% vs. 93.3% for SRS vs. FSRT groups respectively (P=.62). For benign meningiomas, the three-year TC were 92.9% vs. 92.3% for the SRS group (29 patients) vs. FSRT group (14 patients) respectively (P=.77). Two patients in the SRS group and one in the FSRT group developed late complications.Conclusion:Preliminary data suggest that SRS is a safe and effective treatment for patients with benign meningiomas. Fractionated stereotactic radiation therapy with conventional fractionation appeared to be an effective and safe treatment alternative for patients not appropriate for SRS. A longer follow-up is required to determine the long-term efficacy and the toxicity of these treatment modalities.

PD-0803 LINAC-Hypofractionated Stereotactic Radiation Therapy in Five Fractions for Vestibular Schwannoma

2021 ◽  
Vol 161 ◽  
pp. S636-S637
Author(s):  
A. Gawish ◽  
A. Mpotsaris ◽  
I. Sandalcioglu ◽  
K.P. Stein ◽  
T. Brunner ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Vestibular Schwannoma ◽  
Stereotactic Radiation Therapy ◽  
Stereotactic Radiation
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