Risk of Locoregional Recurrence in Triple Negative Breast Cancer Patients Treated by Breast Conserving Therapy vs. Mastectomy: A Population-based Study

2010 ◽  
Vol 78 (3) ◽  
pp. S161
Author(s):  
J.F. Cuartero ◽  
J. Hanson ◽  
Z. Gabos ◽  
J. Deschennes ◽  
S. Sabri ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Triple Negative Breast Cancer ◽  
Locoregional Recurrence ◽  
Triple Negative ◽  
Breast Conserving Therapy ◽  
Population Based ◽  
Breast Cancer Patients ◽  
Population Based Study

scholarly journals Study of the Genetic Variants in BRCA1/2 and Non-BRCA Genes in a Population-Based Cohort of 2155 Breast/Ovary Cancer Patients, Including 443 Triple-Negative Breast Cancer Patients, in Argentina

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2711
Author(s):  
Angela R. Solano ◽  
Pablo G. Mele ◽  
Fernanda S. Jalil ◽  
Natalia C. Liria ◽  
Ernesto J. Podesta ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Population Based ◽  
Breast Cancer Patients ◽  
Ovary Cancer ◽  
Brca Gene ◽  
Pathogenic Variants ◽  
Brca Genes

Gene/s sequencing in hereditary breast/ovary cancer (HBOC) in routine diagnosis is challenged by the analysis of panels. We aim to report a retrospective analysis of BRCA1/2 and non-BRCA gene sequencing in patients with breast/ovary cancer (BOC), including triple-negative breast cancer (TNBC), in our population. In total 2155 BOC patients (1900 analyzed in BRCA1/2 and 255 by multigenic panels) gave 372 (17.2.6%) and 107 (24.1%) likely pathogenic/pathogenic variants (LPVs/PVs), including BRCA and non-BRCA genes, for the total and TNBC patients, respectively. When BOC was present in the same proband, a 51.3% rate was found for LPVs/PVs in BRCA1/2. Most of the LPVs/PVs in the panels were in BRCA1/2; non-BRCA gene LPVs/PVs were in CDH1, CHEK2, CDKN2A, MUTYH, NBN, RAD51D, and TP53. TNBC is associated with BRCA1/2 at a higher rate than the rest of the breast cancer types. The more prevalent PVs in BRCA1/2 genes (mostly in BRCA1) do not rule out the importance to panels of genes, although they are certainly far from shedding light on the gap of the 85% predicted linkage association of BOC with BRCA1/2 and are still not elucidated.

Antiestrogen use in breast cancer patients reduces the risk of subsequent lung cancer: A population-based study

2017 ◽  
Vol 48 ◽  
pp. 22-28 ◽  
Author(s):  
Sung-Chao Chu ◽  
Chia-Jung Hsieh ◽  
Tso-Fu Wang ◽  
Mun-Kun Hong ◽  
Tang-Yuan Chu
Keyword(s):  
Breast Cancer ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Population Based ◽  
Breast Cancer Patients ◽  
Population Based Study
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