Comparison of IGRT Registration Strategies for Optimal Coverage of Primary Lung Tumors and Involved Nodes Based on Multiple Four-Dimensional CT Scans Obtained Throughout the Radiotherapy Course

2012 ◽  
Vol 82 (4) ◽  
pp. 1541-1548 ◽  
Author(s):  
Nasiruddin Mohammed ◽  
Larry Kestin ◽  
Inga Grills ◽  
Chirag Shah ◽  
Carri Glide-Hurst ◽  
...  
Keyword(s):  
Lung Tumors ◽  
Ct Scans ◽  
Primary Lung Tumors

scholarly journals Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Jin Li ◽  
Qian Xu ◽  
Cunhua Mao ◽  
Yuliang Liu
Keyword(s):  
Lung Cancer ◽  
Contrast Agents ◽  
Adverse Reactions ◽  
Lung Tumors ◽  
Ct Imaging ◽  
Ct Scans ◽  
Imaging Features ◽  
Display Time ◽  
Imaging Characteristics ◽  
Primary Lung Tumors

As one of the conventional methods of lung cancer detection, computed tomography (CT) usually requires the use of contrast agents to enhance the imaging effect. Conventional iodine contrast agents have poor signal-to-noise ratio and are prone to adverse reactions. It is necessary to find more effective and safe contrast agents for CT scans. The gold nanoparticles with secondary electron effect and photoelectric absorption effect can prolong the display time of the patient’s blood circulation after being injected into the patient’s body, which makes the nanocontrast agent a research hotspot in the field of CT imaging. In this study, ultrasmall gold nanoclusters with a diameter of about 5 nm were used as the contrast agent in CT scans. It was found that CT scans based on nanocontrast agents can obtain high-quality lung cancer imaging images, and the patient has no obvious adverse reactions. When observing the CT image, it was found that the stage of lung cancer patients can be clearly distinguished through the CT scan image. When analyzing the consistency of CT imaging and pathological classification, the Kappa value was 0.810, indicating that the two have a high degree of consistency. Therefore, this study believes that the imaging characteristics of primary lung tumors based on nanocontrast agents are highly correlated with their pathological types.

COMPUTED TOMOGRAPHIC APPEARANCE OF PRIMARY LUNG TUMORS IN DOGS

2010 ◽  
Vol 52 (2) ◽  
pp. 168-172 ◽  
Author(s):  
ANGELA J. MAROLF ◽  
DEBRA S. GIBBONS ◽  
BRENDAN K. PODELL ◽  
RICHARD D. PARK
Keyword(s):  
Lung Tumors ◽  
Computed Tomographic ◽  
Primary Lung Tumors

PO-1019: Long term outcomes and lung function evolution of primary lung tumors treated with Cyberknife SABR

2020 ◽  
Vol 152 ◽  
pp. S543-S544
Author(s):  
F. Sacino ◽  
N. Jansen ◽  
C. Mievis ◽  
L. Seidel ◽  
S. Cucchiaro ◽  
...  
Keyword(s):  
Lung Function ◽  
Lung Tumors ◽  
Long Term Outcomes ◽  
Primary Lung Tumors

scholarly journals Prognostic factors and clinical outcomes after stereotactic radiotherapy for primary lung tumors

2020 ◽  
Vol 25 (6) ◽  
pp. 943-950
Author(s):  
Isabel Rodrigues ◽  
Tiago Figueiredo ◽  
João Gagean ◽  
Carolina Ferreira ◽  
André Laranja ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Clinical Outcomes ◽  
Stereotactic Radiotherapy ◽  
Lung Tumors ◽  
Primary Lung Tumors

scholarly journals Prognostic Implication of Predominant Histologic Subtypes of Lymph Node Metastases in Surgically Resected Lung Adenocarcinoma

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Kenichi Suda ◽  
Katsuaki Sato ◽  
Shigeki Shimizu ◽  
Kenji Tomizawa ◽  
Toshiki Takemoto ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lung Adenocarcinoma ◽  
Lymph Node Metastases ◽  
Lung Tumor ◽  
International Association ◽  
Lung Tumors ◽  
Prognostic Implication ◽  
Primary Lung Tumors ◽  
Node Metastases ◽  
Histologic Subtypes

The International Association for the Study of Lung Cancer, American Thoracic Society, and European Respiratory Society (IASLC/ATS/ERS) proposed a new classification for lung adenocarcinoma (AD) based on predominant histologic subtypes, such as lepidic, papillary, acinar, solid, and micropapillary; this system reportedly reflects well outcomes of patients with surgically resected lung AD. However, the prognostic implication of predominant histologic subtypes in lymph nodes metastases is unclear so far. In this study, we compared predominant subtypes between primary lung tumors and lymph node metastatic lesions in 24 patients with surgically treated lung adenocarcinoma with lymph node metastases. Additionally, we analyzed prognostic implications of these predominant histologic subtypes. We observed several discordance patterns between predominant subtypes in primary lung tumors and lymph node metastases. Concordance rates were 22%, 64%, and 100%, respectively, in papillary-, acinar-, and solid-predominant primary lung tumors. We observed that the predominant subtype in the primary lung tumor (HR 12.7,P = 0.037), but not that in lymph node metastases (HR 0.18,P = 0.13), determines outcomes in patients with surgically resected lung AD with lymph node metastases.

RADIOGRAPHIC CHARACTERIZATION OF PRIMARY LUNG TUMORS IN 74 DOGS

2014 ◽  
Vol 55 (5) ◽  
pp. 480-487 ◽  
Author(s):  
Laura E. Barrett ◽  
Rachel E. Pollard ◽  
Allison Zwingenberger ◽  
Alexandra Zierenberg-Ripoll ◽  
Katherine A. Skorupski
Keyword(s):  
Lung Tumors ◽  
Primary Lung Tumors

Abstract 3750: Functional analysis of the Fanconi Anemia pathway in primary lung tumors

2010 ◽  
Author(s):  
Wenrui Duan ◽  
Li Gao ◽  
Xin Wu ◽  
Weiqiang Zhao ◽  
Marino Leon ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Fanconi Anemia ◽  
Lung Tumors ◽  
Fanconi Anemia Pathway ◽  
Primary Lung Tumors

Interobserver and Intraobserver Variability in Measurement of Non–Small-Cell Carcinoma Lung Lesions: Implications for Assessment of Tumor Response

2003 ◽  
Vol 21 (13) ◽  
pp. 2574-2582 ◽  
Author(s):  
Jeremy J. Erasmus ◽  
Gregory W. Gladish ◽  
Lyle Broemeling ◽  
Bradley S. Sabloff ◽  
Mylene T. Truong ◽  
...  
Keyword(s):  
Tumor Size ◽  
Tumor Response ◽  
Lung Tumors ◽  
World Health ◽  
Ct Scans ◽  
Intraobserver Variability ◽  
Who Criteria ◽  
Significant Difference ◽  
Misclassification Rates ◽  
Serial Measurements

Purpose: Response of solid malignancies to therapy is usually determined by serial measurements of tumor size. The purpose of our study was to assess the consistency of measurements performed by readers evaluating lung tumors. Materials and Methods: The study group was composed of 33 patients with lung tumors more than 1.5 cm. Bidimensional (BD) and unidimensional (UD) measurements were performed on computed tomography (CT) scans according to the World Health Organization (WHO) criteria and the Response Evaluation Criteria in Solid Tumors (RECIST), respectively. Measurements were performed independently by five thoracic radiologists using printed film and were repeated after 5 to 7 days. Inter- and intraobserver measurement variations were estimated through statistical modeling. Results: There were 40 tumors with an average size of 1.8 to 8.0 cm (mean, 4.1 cm). Analysis of variance showed a significant difference (P < .05) among readers and among the measured nodules for UD and BD measurements. Interobserver misclassification rates were more than intraobserver misclassification rates using either progressive disease or response criteria. The probability of misclassifying a tumor with the WHO criteria or RECIST was greatest with interobserver measurements when criteria for progression (43% BD, 30% UD) were used and lowest with intraobserver measurements when criteria for response (2.5% BD, 3.0% UD) were used. In addition, interobserver misclassification rates were more than intraobserver misclassification rates for both regular and irregular tumors. Conclusion: Measurements of lung tumor size on CT scans are often inconsistent and can lead to an incorrect interpretation of tumor response. Consistency can be improved if the same reader performs serial measurements for any one patient.

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