Demographics, Disparities, and Survival in Young Patients With Oral Cavity Squamous Cell Carcinoma: A Population-Level Analysis of 3828 Cases

2016 ◽  
Vol 94 (4) ◽  
pp. 912-913
Author(s):  
K. Zhan ◽  
E.A. Nicolli ◽  
T. Day
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Young Patients ◽  
Population Level ◽  
Level Analysis

Squamous cell carcinoma of the oral cavity in young patients: Vall D’Hebron hospital experience

2013 ◽  
Vol 42 (10) ◽  
pp. 1278
Author(s):  
A. Mogedas-Vegara ◽  
C. Bescós-Atín ◽  
A. Navaro-Jimenez ◽  
M. Alberola-Ferranti
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Young Patients ◽  
Hospital Experience

scholarly journals EP-1201 Outcomes in young patients (<40) treated for oral cavity squamous cell carcinoma in the modern era

2019 ◽  
Vol 133 ◽  
pp. S666
Author(s):  
A. Billfalk Kelly ◽  
L. Lin ◽  
W. Xu ◽  
S.H. Huang ◽  
R. Wu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Young Patients ◽  
Modern Era

Squamous cell carcinoma of the oral cavity in young patients: a matched-pair analysis

2007 ◽  
Vol 265 (S1) ◽  
pp. 57-61 ◽  
Author(s):  
Hsu-Chueh Ho ◽  
Moon-Sing Lee ◽  
Shih-Hsuan Hsiao ◽  
Juen-Haur Hwang ◽  
Shih-Kai Hung ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Young Patients ◽  
Matched Pair ◽  
Matched Pair Analysis ◽  
Pair Analysis

Clinicopathological features of squamous cell carcinoma of the oral cavity and oropharynx in young patients

2018 ◽  
Vol 56 (4) ◽  
pp. 332-337 ◽  
Author(s):  
R.C.-P. Martinez ◽  
H.P. Sathasivam ◽  
B. Cosway ◽  
V. Paleri ◽  
S. Fellows ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Young Patients ◽  
Clinicopathological Features

Squamous cell carcinoma of the oral cavity in young patients under 40 years

1997 ◽  
Vol 26 ◽  
pp. 220
Author(s):  
R. Martin-Granizo ◽  
F. Rodriguez ◽  
L. Naval ◽  
A. Padron ◽  
P. Rubio ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Young Patients

Outcomes of Young Patients With Oral Cavity Squamous Cell Carcinoma

2015 ◽  
Vol 93 (3) ◽  
pp. S214
Author(s):  
J.L. Shah ◽  
T. Bui ◽  
M. Kaplan ◽  
A.D. Colevas ◽  
Q.T. Le ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Young Patients

Spindle Cell Carcinoma of the Tongue: Fallacies in Its Diagnosis

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Cell Population ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Biphasic Tumor ◽  
Carcinoma Of The Tongue ◽  
Ihc Markers

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.

PD-L1 and survival in oral cavity squamous cell carcinoma

2020 ◽  
Vol 25 (4) ◽  
pp. 287-294
Author(s):  
S. I. Kutukova ◽  
N. P. Beliak ◽  
G. A. Raskin ◽  
M. S. Mukhina ◽  
Yu. V. Ivaskova ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Tumor Cells ◽  
Squamous Cell ◽  
Immune Cells ◽  
Negative Impact ◽  
Progression Free Survival ◽  
Negative Effect ◽  
Effect Of Pd

Relevance. Prognostic value of PD-L1 expression in oral cavity squamous cell carcinoma (OCSCC) and its effect on survival is still controversial. It should be to determine the prognostic role of PD-L1 expression on tumor and immune cells of OCSCC and assess their effect on overall survival (OS) and progression-free survival (PFS).Materials and methods. A prospective study included 145 patients, first diagnosed with OCSCC. PD-L1 expression on tumor and immune cells, infiltrating tumor and its microenvironment, was assessed in all tumor samples by IHC, CPS was calculated. Cut-off values were determined by ROC analysis for identification of PD-L1 expression effect on OS and PFS.Results. Most patients with oral mucosa squamous cell carcinoma showed positive expression of PD-L1 on tumor (77.2%) and immune cells (92.4%). The median PD-L1 expression on tumor cells was 13.5% [1.0-40.0], the median PD-L1 expression on immune cells was 5.0% [1.0-11.0], and the median CPS – 18.0 [3.0-7.8]. Univariate and multivariate analyses revealed a significant negative effect of PD-L1 expression on immune cells ≤ 7% on OS (HR 0.66; 95% CI 0.45-0.93; p = 0.0498); PD-L1 expression in tumor cells ≤ 15% (HR 0.65; 95% CI 0.43-0.98; p = 0.0416) and CPS ≤ 21 (HR 0.62; 95% CI 0.44-0.92; p = 0.0183) for PFS. PD-L1 expression in tumor cells ≤ 6% (HR 0.71; 95% CI 0.47-1.08; p = 0.1096) and CPS ≤ 7 (RR 0.67; 95% CI 0.44-1.01; p = 0.0575) had a confident tendency to negative impact on OS.Conclusion. Positive PD-L1 expression in tumor and immune cells as well as CPS are effective additional factors in the prognosis of the disease course, OS and PFS in patients with OCSCC.

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