Structural design and performance of the first hepatic portal blood flow blocker

Abstract Laparoscopic surgery has been gradually promoted by people because of its advantages of small trauma and quick recovery. However, the operation is difficult, the first hepatic portal should be completely fastened during the operation. In this paper, through the study of the existing structure of the blocker, a kind of blood flow blocker for the first hepatic hilum blocking under laparoscope is designed. All kinds of parameters were calibrated through equation calculation, and the pressure guiding the blood flow blocking of hepatic portal during operation was calculated. The dynamic analysis was carried out with ANSYS software, and it was found that the fluid movement state was most uniform when the airflow velocity reached 8m/s. The experimental apparatus was set up to simulate the process of hepatic portal vein being blocked in vitro, then the feasibility of blocking effect was evaluated. Finally, it is concluded that the designed blood flow blocking device can have good blocking effect on blood vessels.

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Hepatic steroid inactivating enzymes, hepatic portal blood flow and corpus luteum blood perfusion in cattle

Reproduction in Domestic Animals ◽

10.1111/rda.13166 ◽

2018 ◽

Vol 53 (3) ◽

pp. 751-758 ◽

Cited By ~ 5

Author(s):

CG Hart ◽

BE Voelz ◽

KE Brockus ◽

CO Lemley

Keyword(s):

Blood Flow ◽

Corpus Luteum ◽

Blood Perfusion ◽

Portal Blood Flow ◽

Portal Blood ◽

Hepatic Portal

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INFLUENCE OF IONOPHORE ADDITION TO ROUGHAGE AND HIGH-CONCENTRATE DIETS ON PORTAL BLOOD FLOW AND NET NUTRIENT FLUX IN CATTLE

Canadian Journal of Animal Science ◽

10.4141/cjas88-047 ◽

1988 ◽

Vol 68 (2) ◽

pp. 419-429 ◽

Cited By ~ 17

Author(s):

D. L. HARMON ◽

T. B. AVERY ◽

G. B. HUNTINGTON ◽

P. J. REYNOLDS

Keyword(s):

Blood Flow ◽

Oxygen Consumption ◽

Latin Square ◽

Portal Blood Flow ◽

Nutrient Flux ◽

Portal Blood ◽

Beef Steers ◽

Beef Heifers ◽

Net Flux ◽

Hepatic Portal

Two experiments using cattle with chronic hepatic-portal and arterial catheters were conducted to investigate effects of ionophore addition to roughage and high-concentrate diets on net nutrient flux across portal-drained viscera. Monensin and salinomycin added to a high-concentrate diet fed to three beef heifers in a Latin square design (exp. 1) increased the net portal flux of propionate (P < 0.05) and glutamate (P < 0.05) with a tendency for increased portal blood flow. Two beef steers (exp. 2) were fed alfalfa with monensin (300 mg d−1) for 22 d prior to dietary monensin and samples were taken on days −3, 0, 1,2, 4, 9, 16, 32, and 35 relative to monensin removal. Portal blood flow and gut oxygen consumption decreased (P < 0.05) following monensin removal until day 9, then remained relatively constant. Use of glucose by portal-drained viscera decreased (P < 0.05) until day 16, then returned towards initial values, while net appearance of L-lactate decreased linearly (P < 0.05). After monensin removal from the diet, the net portal flux of L-lactate, ammonia-N, acetate, propionate, isobutyrate, and 3-methylbutyrate were reduced (P < 0.05). These reductions were largely the result of decreased portal blood flow. In both experiments, dietary ionophores affected net flux across portal-drained viscera for several metabolites. These changes may differ, however, with roughage level and ionophore fed. Key words: Bovine, ionophore, absorption, blood flow

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The effects of feeding and acute cold exposure on the visceral release of volatile fatty acids, estimated hepatic uptake of propionate and release of glucose, and plasma insulin concentration in sheep

British Journal Of Nutrition ◽

10.1079/bjn19780028 ◽

1978 ◽

Vol 39 (1) ◽

pp. 219-226 ◽

Cited By ~ 20

Author(s):

G. E. Thompson ◽

J. M. Bassett ◽

A. W. Bell

Keyword(s):

Blood Flow ◽

Cold Exposure ◽

Plasma Insulin ◽

Volatile Fatty Acids ◽

Environmental Temperature ◽

Portal Blood Flow ◽

Portal Blood ◽

Insulin Concentration ◽

Plasma Insulin Concentration ◽

Hepatic Portal

1. Five sheep were given a meal while they were in a neutral environmental temperature (15–20°) and while acutely exposed to a moderately cold (1°, wind speed 2 m/s) environment.2. Before and at various times after feeding measurements were made of hepatic portal blood flow and the concentration of volatile fatty acids (VFA) and glucose in arterial, hepatic portal and hepatic venous blood plasma. From these measurements the net rate of release of VFA from the viscera was calculated, and the uptake of propionate and output of glucose by the liver was estimated, assuming hepatic arterial blood flow to be 20% of portal flow. The concentration of insulin in arterial and portal venous plasma was also measured.3. The change in environmental temperature did not affect the time taken by the animals to eat the meal completely.4. After feeding, in the neutral environment, there were significant increases in portal blood flow and release of VFA into the portal bloodstream. The uptake of propionate by the liver increased, significantly, and output of glucose also increased, but not significantly. Plasma insulin concentration also increased after feeding.5. During cold exposure portal blood flow was consistently higher, before and after feeding, than it was in the neutral environment. The release of VFA into the portal blood was also consistently greater during cold exposure, especially the release of propionate after feeding. Associated with this was an extra uptake of propionate and output of glucose by the liver. Plasma insulin concentration was slightly higher in the cold environment than the neutral environment before the animals were fed, but this difference was not apparent at any other time.

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