Biosynthesis of lead oxide and cerium oxide nanoparticles and their cytotoxic activities against colon cancer cell line

Author(s):  
Ebrahim Nazaripour ◽  
Farideh Mousazadeh ◽  
Mehdi Doosti Moghadam ◽  
Kazem Najafi ◽  
Fariba Borhani ◽  
...  
2022 ◽  
Author(s):  
Nidhi chaudhary ◽  
Manish Pratap Singh ◽  
Preeti Sirohi ◽  
Shadma Afzal ◽  
Nand K. Singh

Abstract ObjectiveIn the present study, we green synthesized ZnO NPs (zinc oxide nanoparticles) from Senna occidentalis leaf extract which were subsequently assessed for their cytotoxic and antioxidant activity on colon cancer SW480 cell line.Results Zinc oxide nanoparticles were characterized by using UV-Vis spectroscopy, X-ray diffractometer (XRD), Particle size analyzer (PSA), Fourier transform infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FE-SEM), Energy-dispersive X-ray (EDS) and atomic force microscope (AFM) analysis. The PSA, XRD and AFM showed 20-50 nm size and nearly cuboidal and irregular shaped of the ZnO NPs. The synthesized ZnO nanoparticles were evaluated for their anticancer activity on human colon cancer cell line (SW480) by using MTT and neutral red uptake assay. The SW480 colon cancer cells were treated with various concentrations of ZnO NPs in the range of 20–100 µg/ml for 2 hrs. The result showed that ZnO NPs could reduce cell viability of SW480 cells up to 50% at the concentration of 100 µg/ml and induce membrane leakage in a concentration dependent manner.ConclusionThe anticancer activity of zinc oxide nanoparticles has showed that these can be used as effective anti-cancer agent against colon cancer cell lines (SW480).


2020 ◽  
Vol 582 ◽  
pp. 119320
Author(s):  
Mohammad Hasan Faghfoori ◽  
Hamed Nosrati ◽  
Hamed Rezaeejam ◽  
Jalil Charmi ◽  
Saeed Kaboli ◽  
...  

Oncogene ◽  
2002 ◽  
Vol 21 (38) ◽  
pp. 5906-5911 ◽  
Author(s):  
Shigeki Sekine ◽  
Tatsuhiro Shibata ◽  
Michiie Sakamoto ◽  
Setsuo Hirohashi

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jigang Wang ◽  
Jianbin Zhang ◽  
Chong-Jing Zhang ◽  
Yin Kwan Wong ◽  
Teck Kwang Lim ◽  
...  

2015 ◽  
Vol 24 (10) ◽  
pp. 1686-1694 ◽  
Author(s):  
Jennifer Lee ◽  
Uwe Warnken ◽  
Martina Schnölzer ◽  
Johannes Gebert ◽  
Jürgen Kopitz

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