A New Digital Tool to Assess Allergic Rhinitis Symptom Control

ABSTRACT Objective: Although there is no consensus regarding the etiology of paranasal mucous retention cysts (MRCs) in the literature, several studies suggest an allergic etiology. This study aimed to investigate a potential association between paranasal MRCs diagnosed with MRI scans and allergic sensitization in the pediatric population. Materials and Methods: A total of 4559 MRI scans were retrospectively evaluated for MRC in patients who presented to the pediatric neurology outpatient clinic with headache complaints. Fifty children with MRI findings conclusive for paranasal MRC and 50 children without such findings were included in the study. All study and control patients were invited for atopy/allergy evaluation. Total IgE measurements, blood eosinophil levels, nasal smear and skin prick tests were performed to evaluate the allergic status of the children. In addition, an allergic rhinitis symptom questionnaire was administered. Results: The mean age was 13.0±2.8 years (median 14 y, range 6-18 y) with a female-to-male ratio of 1.4:1 in the study group. The prevalence of MRC was found to be 1.1% (50 in 4559). The two groups did not differ with regard to the frequency of blood eosinophilia, nasal eosinophilia, serum IgE levels, and allergic rhinitis symptom severity (p>0.05). Positive skin test for at least one of the allergens tested was more common in the MRC group than the controls (40% vs. 16%, p=0.007). Multivariate analysis identified that a positive skin prick test for at least one allergen was a significant independent predictor of MRC (OR, 4.6; 95% CI 1.2-17.0, p=0.023). Conclusion: Our study showed that paranasal MRCs were significantly more frequent in atopic children compared to controls. Additionally, MRCs were found to be strongly associated with allergic sensitization. Keywords: Cysts, allergic rhinitis, children, diagnostic tests, signs and symptoms

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A new therapy (MP29-02*) effectively targets the entire seasonal allergic rhinitis symptom complex

Clinical and Translational Allergy ◽

10.1186/2045-7022-3-s2-p45 ◽

2013 ◽

Vol 3 (S2) ◽

Author(s):

David Price ◽

Jean Bousquet ◽

Claus Bachert ◽

Wytske Fokkens ◽

Glenis Scadding ◽

...

Keyword(s):

Allergic Rhinitis ◽

Seasonal Allergic Rhinitis ◽

New Therapy ◽

Allergic Rhinitis Symptom ◽

Rhinitis Symptom ◽

Symptom Complex

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Interventions Delivered in the Community Pharmacy to Manage Allergic Rhinitis- A Systematic Review of the Literature

Pharmacy ◽

10.3390/pharmacy8020080 ◽

2020 ◽

Vol 8 (2) ◽

pp. 80

Author(s):

Jéssica José ◽

Biljana Cvetkovski ◽

Vicky Kritikos ◽

Rachel Tan ◽

Sinthia Bosnic-Anticevich ◽

...

Keyword(s):

Systematic Review ◽

Allergic Rhinitis ◽

Community Pharmacy ◽

Selection Process ◽

Symptom Control ◽

Review Of The Literature ◽

Inclusion Criteria ◽

The Impact ◽

Valuable Role

Pharmacists have a valuable role in the management of allergic rhinitis (AR) at the community pharmacy level. This role has been reported extensively in numerous papers. However, a systematic review of the available literature and a comprehensive analysis of the outcomes has not been published. This systematic review aimed to evaluate the impact of interventions developed by pharmacists on clinical AR outcomes. A thorough search was performed in three electronic databases, including studies published between January 2000 and June 2019. After the selection process, only three articles met the inclusion criteria and were further analysed. Despite the scarcity of the available studies, in all of them was clear that the pharmacist plays a pivotal role in the management of AR, significantly improving the patients’ quality of life and symptom control. This systematic review also stresses the utmost importance to investigate and report practices and interventions developed by pharmacists using measurable outcomes.

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Daily versus self-adjusted dosing of topical mometasone furoate nasal spray in patients with allergic rhinitis: randomised, controlled trial

The Journal of Laryngology & Otology ◽

10.1017/s002221510999171x ◽

2009 ◽

Vol 124 (4) ◽

pp. 397-401 ◽

Cited By ~ 6

Author(s):

M A Khan ◽

A S Abou-Halawa ◽

A A Al-Robaee ◽

A A Alzolibani ◽

H A Al-Shobaili

Keyword(s):

Allergic Rhinitis ◽

Nasal Cavity ◽

Nasal Spray ◽

Controlled Trial ◽

Symptom Control ◽

Mometasone Furoate ◽

The Self ◽

Cavity Volume ◽

Significant Difference ◽

Randomised Controlled

AbstractBackground:Many patients with allergic rhinitis are reluctant to use daily intranasal steroids for prolonged periods. A self-adjusted regimen which delivers reasonable control of allergic rhinitis may be more acceptable to such patients.Objectives:To compare the efficacy of daily use of mometasone furoate nasal spray, versus a self-adjusted regimen, in patients with chronic allergic rhinitis, in terms of symptom control and nasal volume change.Setting:Ambulatory visits in an office setting.Patients and methods:Sixty patients with chronic allergic rhinitis were randomised: 30 were prescribed mometasone furoate nasal spray once daily for six weeks, while 30 were prescribed the same spray daily for one week, every alternate day for one week and then on a self-adjusted regimen for four weeks. Patients kept a symptom diary documenting sneezing, rhinorrhoea, nasal blockage and nasal itching. Acoustic rhinometry was used to measure the total nasal cavity volume at the first visit and at the end of the treatment period.Results:The total nasal score on treatment days showed an improvement in both groups, compared with baseline measurements. There was no significant difference in total nasal scores between the two groups, except on days 10 (p = 0.043), 20 (p = 0.008), 23 (p = 0.19), 30 (p = 0.008) and 37 (p = 0.000), when the daily group's total nasal score was significantly lower than the self-adjusted group's total nasal score, and on day 8 (p = 0.004), when the self-adjusted group's total nasal score was significantly lower than the daily group's total nasal score. Total nasal cavity volume significantly increased in both groups (p = 0.0001), with no statistically significant difference between the groups.Conclusions:Self-adjusted dosage of mometasone furoate nasal spray gives reasonable control of allergic rhinitis (albeit with some ‘breakthrough’ symptoms). Patients should learn how to control these symptoms with the least number of steroid doses.

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