scholarly journals Interventions Delivered in the Community Pharmacy to Manage Allergic Rhinitis- A Systematic Review of the Literature

Pharmacy ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 80
Author(s):  
Jéssica José ◽  
Biljana Cvetkovski ◽  
Vicky Kritikos ◽  
Rachel Tan ◽  
Sinthia Bosnic-Anticevich ◽  
...  
Keyword(s):  
Systematic Review ◽  
Allergic Rhinitis ◽  
Community Pharmacy ◽  
Selection Process ◽  
Symptom Control ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
The Impact ◽  
Valuable Role

Pharmacists have a valuable role in the management of allergic rhinitis (AR) at the community pharmacy level. This role has been reported extensively in numerous papers. However, a systematic review of the available literature and a comprehensive analysis of the outcomes has not been published. This systematic review aimed to evaluate the impact of interventions developed by pharmacists on clinical AR outcomes. A thorough search was performed in three electronic databases, including studies published between January 2000 and June 2019. After the selection process, only three articles met the inclusion criteria and were further analysed. Despite the scarcity of the available studies, in all of them was clear that the pharmacist plays a pivotal role in the management of AR, significantly improving the patients’ quality of life and symptom control. This systematic review also stresses the utmost importance to investigate and report practices and interventions developed by pharmacists using measurable outcomes.

scholarly journals The Impact of Autoantibodies on IVF Treatment and Outcome: A Systematic Review

2019 ◽  
Vol 20 (4) ◽  
pp. 892 ◽  
Author(s):  
Mara Simopoulou ◽  
Konstantinos Sfakianoudis ◽  
Evangelos Maziotis ◽  
Sokratis Grigoriadis ◽  
Polina Giannelou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Inclusion Criteria ◽  
Vitro Fertilization ◽  
Different Types ◽  
Significant Research ◽  
Central Database ◽  
The Impact

The role of autoantibodies in in vitro fertilization (IVF) has been discussed for almost three decades. Nonetheless, studies are still scarce and widely controversial. The aim of this study is to provide a comprehensive systematic review on the possible complications associated to autoantibodies (AA) impeding the chances of a successful IVF cycle. An Embase, PubMed/Medline and Cochrane Central Database search was performed on 1 December 2018, from 2006 until that date. From the 598 articles yielded in the search only 44 relevant articles ultimately fulfilled the inclusion criteria and were qualitatively analyzed. Five subsets of results were identified, namely, thyroid related AA, anti-phospholipid antibodies, anti-nuclear antibodies, AA affecting the reproductive system and AA related to celiac disease. It may be implied that the majority of auto-antibodies exert a statistically significant effect on miscarriage rates, whereas the effects on clinical pregnancy and live birth rates differ according to the type of auto-antibodies. While significant research is performed in the field, the quality of evidence provided is still low. The conduction of well-designed prospective cohort studies is an absolute necessity in order to define the impact of the different types of autoantibodies on IVF outcome.

scholarly journals The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Samantha W. Jones ◽  
Amy L. Ball ◽  
Amy E. Chadwick ◽  
Ana Alfirevic
Keyword(s):  
Systematic Review ◽  
Mitochondrial Dna ◽  
Drug Response ◽  
Drug Efficacy ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Mtdna Variation ◽  
Pubmed Database ◽  
Mtdna Variants ◽  
The Impact

Background: The triad of drug efficacy, toxicity and resistance underpins the risk-benefit balance of all therapeutics. The application of pharmacogenomics has the potential to improve the risk-benefit balance of a given therapeutic via the stratification of patient populations based on DNA variants. A growth in the understanding of the particulars of the mitochondrial genome, alongside the availability of techniques for its interrogation has resulted in a growing body of literature examining the impact of mitochondrial DNA (mtDNA) variation upon drug response.Objective: To critically evaluate and summarize the available literature, across a defined period, in a systematic fashion in order to map out the current landscape of the subject area and identify how the field may continue to advance.Methods: A systematic review of the literature published between January 2009 and December 2020 was conducted using the PubMed database with the following key inclusion criteria: reference to specific mtDNA polymorphisms or haplogroups, a core objective to examine associations between mtDNA variants and drug response, and research performed using human subjects or human in vitro models.Results: Review of the literature identified 24 articles reporting an investigation of the association between mtDNA variant(s) and drug efficacy, toxicity or resistance that met the key inclusion criteria. This included 10 articles examining mtDNA variations associated with antiretroviral therapy response, 4 articles examining mtDNA variants associated with anticancer agent response and 4 articles examining mtDNA variants associated with antimicrobial agent response. The remaining articles covered a wide breadth of medications and were therefore grouped together and referred to as “other.”Conclusions: Investigation of the impact of mtDNA variation upon drug response has been sporadic to-date. Collective assessment of the associations identified in the articles was inconclusive due to heterogeneous methods and outcomes, limited racial/ethnic groups, lack of replication and inadequate statistical power. There remains a high degree of idiosyncrasy in drug response and this area has the potential to explain variation in drug response in a clinical setting, therefore further research is likely to be of clinical benefit.

scholarly journals The Impacts of Educational Asthma Interventions in Schools: A Systematic Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Ana Carla Carvalho Coelho ◽  
Laís Souza Barretto Cardoso ◽  
Carolina de Souza-Machado ◽  
Adelmir Souza-Machado
Keyword(s):  
Systematic Review ◽  
Health Professionals ◽  
Developed Countries ◽  
Educational Interventions ◽  
School Staff ◽  
Review Of The Literature ◽  
Controlled Clinical Trials ◽  
Asthma Symptoms ◽  
The Impact

Objective. To review the literature on the impact of educational asthma interventions in schools regarding the knowledge and morbidity of the disease among children and adolescents.Methods. A systematic review was conducted for controlled clinical trials investigating the effectiveness of educational asthma interventions for students, asthmatic or nonasthmatic, families, and school staff. Databases were CENTRAL, PubMed, LILACS, MEDLINE, and SciELO. Articles published in any language were considered, in the period from 2005 to 2014, according to the PRISMA guidelines.Results. Seventeen articles were selected (N=5,879 subjects). 94% of the interventions (16 of 17 studies) were applied in developed countries that were led by health professionals and most of them targeted asthmatics. Asthma education promotes the improvement of knowledge about the disease in at least one of the evaluated areas. 29% of the interventions (5 of 17 studies) showed a reduction of the asthma symptoms, 35% (6 of 17 studies) reduction of the hospitalization instances and emergency visits, 29% (5 of 17 studies) reduction of school absenteeism, and 41% (7 of 17 studies) increase in the quality of life of the individuals.Conclusions. Educational interventions in schools raise the awareness of asthma and weaken the impact of morbidity indicators.

scholarly journals Is project-based learning effective among kindergarten and elementary students? A systematic review

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249627
Author(s):  
Marta Ferrero ◽  
Miguel A. Vadillo ◽  
Samuel P. León
Keyword(s):  
Systematic Review ◽  
Elementary Students ◽  
Basic Education ◽  
Project Based Learning ◽  
Control Group ◽  
Inclusion Criteria ◽  
Final Sample ◽  
Educational Implications ◽  
The Impact

Project-based learning (PjBL) is becoming widespread in many schools. However, the evidence of its effectiveness in the classroom is still limited, especially in basic education. The aim of the present study was to perform a systematic review of the empirical evidence assessing the impact of PjBL on academic achievement of kindergarten and elementary students. We also examined the quality of studies, their compliance with basic prerequisites for a successful result, and their fidelity towards the key elements of PBL intervention. For this objective, we conducted a literature search in January 2020. The inclusion criteria for the review required that studies followed a pre-post design with control group and measured quantitatively the impact of PBL on content knowledge of students. The final sample included eleven articles comprising data from 722 students. The studies yielded inconclusive results, had important methodological flaws, and reported insufficient or no information about important aspects of the materials, procedure and key requirements from students and instructors to guarantee the success of PjBL. Educational implications of these results are discussed.

scholarly journals The Impact of Non-Price In-premise Marketing on Food and Beverage Purchasing and Consumer Behaviour: A Systematic Review

2021 ◽  
Author(s):  
Ross Whitehead ◽  
Stefania Greci ◽  
Hilary Thomson ◽  
Gillian Armour ◽  
Kathryn Angus ◽  
...  
Keyword(s):  
Systematic Review ◽  
Public Policy ◽  
English Language ◽  
Consumer Behaviour ◽  
Future Research ◽  
Inclusion Criteria ◽  
Online Purchase ◽  
Food And Beverage ◽  
The Impact

In-premise marketing is commonly used to promote foods that are high in fat, sugar or salt. In order to inform development of public policy in this area, this systematic review sought to determine the quantity and quality of English-language evidence which examines the role and impact of in-premise advertising (e.g., signage, posters) and positional promotions (e.g., checkout displays) on consumer behaviour and diet-related outcomes in retail, out-of-home (i.e., cafes, restaurants, takeaways) and online purchasing environments. Sixty-two studies met inclusion criteria, of which 69% (n=42) were identified as being methodologically weak. The best-available evidence constitutes findings from four methodologically strong studies, and ten moderate studies which are not confounded by additional promotions such as price or availability. These studies predominantly found evidence that in-premise marketing is likely to be successful in influencing consumer behaviour towards targeted items, across retail and out-of-home settings. These findings provide a basis for authorities to consider acting to restrict in-premise marketing of unhealthy foods and encouraging the in-premise marketing of healthier products. This review identified gaps in the evidence available on non-sales outcomes, and on online purchase environments. These gaps, and identified methodological limitations of the extant evidence remain to be addressed by future research.

scholarly journals Effect of COVID-19 on Health-Related Quality of Life in Adolescents and Children: A Systematic Review

2021 ◽  
Vol 18 (9) ◽  
pp. 4563
Author(s):  
Hadi Nobari ◽  
Mohamad Fashi ◽  
Arezoo Eskandari ◽  
Santos Villafaina ◽  
Álvaro Murillo-Garcia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Children And Adolescents ◽  
Negative Impact ◽  
Health Related Quality ◽  
Inclusion Criteria ◽  
Related Quality ◽  
Health Related ◽  
The Impact

The aim of the present systematic review was to assess and provide an up-to-date analysis of the impact of coronavirus disease 2019 (COVID-19) pandemic on the health-related quality of life (HRQoL) of children and adolescents. Thus, an electronic search of the literature, in two well-known databases (PubMed and Web of Science), was performed until February 2021 (without date restriction). PRISMA guideline methodology was employed and data regarding the HRQoL were extracted from eligible studies. Articles were included if they met the following inclusion criteria: (a) children and/or adolescent population (4 to 19 years old); (b) HRQoL as a main assessment; (c) German, Spanish, Portuguese, French, and English language; and (d) pre-pandemic and during pandemic HRQoL data. Following the initial search, 241 possible related articles were identified. A total of 79 articles were identified as duplicates. Moreover, 129 articles were removed after reading the title and abstract. Of the remaining 33 articles, 27 were removed since they were not focused on children or adolescents (n = 19), articles did not report pre- and post- pandemic HRQoL values (n = 6), articles were not focused on HRQoL (n = 6), and one article was an editorial. Finally, six studies fulfilled the inclusion criteria and, therefore, were included in the systematic review. A total of 3177 children and/or adolescents during COVID-19 were included in this systematic review. Three articles showed that COVID-19 pandemic significantly impacted the HRQoL of children and adolescents, and another did not report comparison between pre- and during COVID-19 pandemic, although a reduction in the HRQoL can be observed. Nevertheless, two articles did not find significant changes and another one did not report p-values. Regarding sex differences, only two studies analyzed this topic, observing no differences between girls and boys in the impact of COVID-19 pandemic on HRQoL. Taking into account these results, this systematic review might confirm that COVID-19 has a negative impact on the HRQoL of children and/or adolescents.

Childhood Maltreatment Consequences on Social Pragmatic Communication: A Systematic Review of the Literature

2021 ◽  
Vol 6 (2) ◽  
pp. 262-287
Author(s):  
Yvette D. Hyter
Keyword(s):  
Systematic Review ◽  
Experimental Study ◽  
Child Protection ◽  
Well Being ◽  
Pragmatic Language ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Belief Attribution ◽  
Pragmatic Communication ◽  
The Impact

Purpose Maltreatment is a threat to child health and well-being and negatively influences all aspects of development, including language. Less seems to be known about the consequences that maltreatment has on social pragmatic communication. A systematic review of the literature was performed to summarize existing empirical research on complex trauma (the impact of maltreatment, including abuse and neglect, in the caregiving system) on social pragmatic communication of children and youth. The goal of this review article was to review the empirical evidence of the association between maltreatment and social pragmatic communication profiles of children. Method Research articles published between 1974, when the first comprehensive law of child protection was enacted, and 2020 were reviewed. Seven electronic databases were used to conduct the search for literature using several combined concepts related to social pragmatic communication and maltreatment. The inclusion criteria were that articles addressed any form of maltreatment, included participants aged 18 years or younger, and primarily focused on the impact of maltreatment on social pragmatic communication and that their method and findings were based on an experimental study. Studies were excluded if they were written in a language other than English, focused on adults, did not include the social pragmatic communication and maltreatment concepts, were a systematic review or meta-analysis, or were a theoretical rather than experimental study. A modified version of the Primary Research Appraisal Tool was used to determine key characteristics of each article. Results Thirty-eight articles met inclusion criteria for this study. Findings of these studies provide evidence that maltreatment has an impact on social pragmatic communication including social cognition, perspective taking, and belief attribution; executive functions including working memory; and pragmatic language including narrative discourse and the use of varied communicative functions. Conclusions The major findings have implications for knowledge and skills of speech-language and hearing professionals working with children and adolescents and for the type of assessment and intervention processes used to assess social pragmatic communication. Suggestions for future studies are provided.

scholarly journals The Quality of Life of Patients with HIV/AIDS Undergoing Antiretroviral Therapy: A Systematic Review

Jurnal NERS ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. 50
Author(s):  
Putri Irwanti Sari ◽  
RTS Netisa Martawinarti ◽  
Nurmawati S. Lataima ◽  
Vivi Meiti Berhimpong
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Antiretroviral Therapy ◽  
Side Effects ◽  
Research Articles ◽  
Adherence To Treatment ◽  
Inclusion Criteria ◽  
The Impact ◽  
Hiv Aids

Introduction: Quality of Life (QoL) is one of the most important things for a patient with HIV/AIDS. Good QoL will improve the adherence to treatment, especially antiretroviral therapy. The purpose of this study was to explore about the quality of life of the patients with HIV/AIDS undergoing antiretroviral therapy.Methods: The data was collected through a literature review from electronic databases such as Scopus, ProQuest, Google Scholar and Springerlink journal. The keywords were "quality of life", "HIV/AIDS", "quality of life of patients with HIV/AIDS" or "quality of life and HIV/AIDS and antiretroviral therapy".Results: The researcher obtained 15 articles based on the inclusion criteria. Several research articles that were analyzed showed that the Quality of Life of HIV/AIDS patients undergoing antiretroviral therapy was not all good. This is caused by the side-effects of using antiretroviral therapy and the side-effects that were physical, psychological, social and environmental.Conclusion: The impact of the side effects of antiretroviral therapy has caused the clients with HIV/AIDS to choose other therapies such as ART replacement therapy to improve the quality of life for patients with HIV/AIDS.

scholarly journals Psychological effects of the pandemic on caregivers of older adults: A rapid systematic review

2021 ◽  
Vol 10 (8) ◽  
pp. e13210817125
Author(s):  
Willian Roger Dullius ◽  
Álisson Secchi ◽  
Silvana Alba Scortegagna
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Older Adults ◽  
Sleep Problems ◽  
Poor Quality ◽  
Psychological Effects ◽  
Psychological Interventions ◽  
Inclusion Criteria ◽  
The Impact

The COVID-19 pandemic has rendered numerous impacts on society, especially to caregivers of older adults, who are facing many tasks. These elevated number of demands and modifications can affect these caregivers’ mental health. This study aimed to gather empirical evidence on existing researches about the impact of caregiver’s mental health of older adults during the COVID-19 pandemic. This rapid systematic review, developed from international and Brazilian databases from January/2020 to April/2021, identified 4714 potentially relevant articles, published in English and Portuguese. Eighteen (18) articles that potentially met the inclusion criteria were screened and read. Eleven of them met the inclusion criteria and were selected for this review. Caregivers of older adults demonstrate different psychological manifestations such as higher levels of stress, anxiety, sleep problems, depression, somatic symptoms, and poor quality of life. Those can directly influence the care provided to the older adults. Knowing the effects on the caregivers can be conducted psychological interventions to prevent and minimize impacts in their lives.

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