Hypertensive Disorders of Pregnancy and Recurrent Wheezing: 18 Month Follow-up Of A Birth Cohort Study

Hypertensive disorders of pregnancy account for approximately 22% of all maternal deaths in Latin America and the Caribbean. Pharmacotherapies play an important role in preventing and reducing the occurrence of adverse outcomes. However, the patterns of medications used for treating women with hypertensive disorders of pregnancy (HDP) living in this country is unclear. A population-based birth cohort study including 4262 women was conducted to describe the pattern of use of cardiovascular agents and acetylsalicylic acid between women with and without HDP in the 2015 Pelotas (Brazil) Birth Cohort. The prevalence of maternal and perinatal outcomes in this population was also assessed. HDP were classified according to Ministry of Health recommendations. Medications were defined using the Anatomical Therapeutic Chemical Classification System and the substance name. In this cohort, 1336 (31.3%) of women had HDP. Gestational hypertension was present in 636 (47.6%) women, 409 (30.6%) had chronic hypertension, 191 (14.3%) pre-eclampsia, and 89 (6.7%) pre-eclampsia superimposed on chronic hypertension. Approximately 70% of women with HDP reported not using any cardiovascular medications. Methyldopa in monotherapy was the most frequent treatment (16%), regardless of the type of HDP. Omega-3 was the medication most frequently reported by women without HDP. Preterm delivery, caesarean section, low birth weight, and neonatal intensive care admissions were more prevalent in women with HDP. Patterns of use of methyldopa were in-line with the Brazilian guidelines as the first-line therapy for HDP. However, the large number of women with HDP not using medications to manage HDP requires further investigation.

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Associations of maternal ozone exposures during pregnancy with maternal blood pressure and risk of hypertensive disorders of pregnancy: A birth cohort study in Guangzhou, China

Environmental Research ◽

10.1016/j.envres.2020.109207 ◽

2020 ◽

Vol 183 ◽

pp. 109207

Author(s):

Wenjun Cao ◽

Moran Dong ◽

Xiaoli Sun ◽

Xin Liu ◽

Jianpeng Xiao ◽

...

Keyword(s):

Blood Pressure ◽

Cohort Study ◽

Birth Cohort ◽

Maternal Blood ◽

Birth Cohort Study ◽

Hypertensive Disorders Of Pregnancy ◽

Hypertensive Disorders ◽

Exposures During Pregnancy ◽

Maternal Blood Pressure

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Thyroid autoantibodies in pregnancy are associated with hypertensive disorders of pregnancy: Ma'anshan Birth Cohort Study

Clinical Endocrinology ◽

10.1111/cen.13590 ◽

2018 ◽

Vol 88 (6) ◽

pp. 928-935 ◽

Cited By ~ 4

Author(s):

Yan Han ◽

Lei-jing Mao ◽

Xing Ge ◽

Kun Huang ◽

Shuang-qin Yan ◽

...

Keyword(s):

Cohort Study ◽

Birth Cohort ◽

Birth Cohort Study ◽

Thyroid Autoantibodies ◽

Hypertensive Disorders Of Pregnancy ◽

Hypertensive Disorders ◽

In Pregnancy

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Size at birth and height in early adolescence: a prospective birth cohort study

Cadernos de Saúde Pública ◽

10.1590/s0102-311x2008000400018 ◽

2008 ◽

Vol 24 (4) ◽

pp. 871-878 ◽

Cited By ~ 3

Author(s):

Cora L. P. Araújo ◽

Pedro C. Hallal ◽

Gisele A. Nader ◽

Ana Maria B. Menezes ◽

Cesar G. Victora

Keyword(s):

Cohort Study ◽

Birth Cohort ◽

Early Adolescence ◽

Strong Predictor ◽

Birth Length ◽

Birth Cohort Study ◽

Size At Birth ◽

Prospective Birth Cohort ◽

Prospective Birth Cohort Study

The aim of this study was to evaluate the association between size at birth (birthweight and birth length) and height in early adolescence in a prospective birth cohort study in Pelotas, Rio Grande do Sul, Brazil. Interviews were carried out in 1993, including measurements of birthweight and length, and in 2004-2005, including measurements of weight and height. This analysis includes 4,452 individuals, with a mean age of 11.3 years (standard deviation - SD = 0.3), representing a follow-up rate of 87.5%. Mean height at 11 years was 145.8 cm (SD = 7.9), or 144.9 cm (SD = 7.7) in boys and 146.8 cm (SD = 7.9) in girls. Birthweight and birth length were positively associated with height in early adolescence in the crude analysis, but after adjustment for confounding and for each other, only the effect of birth length was still significant. A one z-score increase in birth length was associated with a 1.63 cm increase in height at 11 years. The present study shows that birth length is a strong predictor of later height, while the effect of birth weight disappears after adjustment for birth length.

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