“Atherogenic index of plasma” (log10 triglyceride/high-density lipoprotein−cholesterol) predicts high blood pressure, diabetes, and vascular events

2010 ◽  
Vol 4 (2) ◽  
pp. 89-98 ◽  
Author(s):  
Altan Onat ◽  
Günay Can ◽  
Hasan Kaya ◽  
Gülay Hergenç
2021 ◽  
Vol 34 ◽  
Author(s):  
Larisse Monteles NASCIMENTO ◽  
Nayara Vieira do Nascimento MONTEIRO ◽  
Thiana Magalhães VILAR ◽  
Cyntia Regina Lúcio de Sousa IBIAPINA ◽  
Karoline de Macedo Gonçalves FROTA

ABSTRACT Objective To investigate the influence of ultra-processed food consumption on anthropometric and atherogenic indices. Methods A cross-sectional study was conducted with 327 adolescents aged 14 to 19 years. Sociodemographic, anthropometric, biochemical, and food consumption data were evaluated. The ratios of atherogenic indices were calculated using the Castelli I (Total Cholesterol/High Density Lipoprotein Cholesterol), Castelli II (Low Density Lipoprotein Cholesterol/High Density Lipoprotein Cholesterol), and estimated Low Density Lipoprotein Cholesterol particle size (Atherogenic Index of Plasma=Triglycerides/High-Density Lipoprotein Cholesterol) indices. Logistic regression was used for the unadjusted and adjusted analysis between ultra-processed foods consumption, anthropometric, and atherogenic indices. The level of significance was 5%. Results Most participants were female (59.3%). Girls had a higher consumption of ultra-processed foods (26.6% vs. 20.5%). Of the total number of adolescents, 16.5% were overweight and 65.7% were from public schools. Adolescents with altered values for the Castelli I and II Index, and for the Atherogenic Index of Plasma had significantly higher weights, Waist Circumference, Waist Circumference/ Height and Body Mass Index/ Age values. The adjusted analysis identified a significant association (Odds ratio=2.29; 95% Confidence interval: 1.23-4.28) between the high consumption of ultra-processed foods and the Castelli II index. Conclusion The associations between atherogenic indices and anthropometric indices and the consumption of ultra-processed foods highlight the negative influence of these foods on adolescents’ cardiovascular health.


2020 ◽  
Vol 17 (8) ◽  
pp. 800-806
Author(s):  
Leigh M. Vanderloo ◽  
Jonathan L. Maguire ◽  
David W. H. Dai ◽  
Patricia C. Parkin ◽  
Cornelia M. Borkhoff ◽  
...  

Background: This study aimed to examine the association between physical activity (PA) and a total cardio metabolic risk (CMR) score in children aged 3–12 years. Secondary objectives were to examine the association between PA and individual CMR factors. Methods: A longitudinal study with repeated measures was conducted with participants from a large primary care practice-based research network in Toronto, Canada. Mixed effects models were used to examine the relationship between parent-reported physical activity and outcome variables (total CMR score, triglycerides, glucose, high-density lipoprotein cholesterol, systolic blood pressure, waist circumference, weight-to-height ratio, and non-high-density lipoprotein cholesterol). Results: Data from 1885 children (6.06 y, 54.4% male) with multiple visits (n = 2670) were included in the analyses. For every unit increase of 60 minutes of PA, there was no evidence of an association with total CMR score (adjusted: −0.02 [−0.014 to 0.004], P = .11]. For the individual CMR components, there was evidence of a weak association between PA and systolic blood pressure (−0.01 [−0.03 to −0.01], P < .001) and waist-to-height ratio (−0.81 [−1.62 to −0.003], P < .001). Conclusion: Parent-reported PA among children aged 3–12 years was not statistically associated with total CMR, but was weakly associated with systolic blood pressure and waist-to-height ratio.


1969 ◽  
Vol 6 (2) ◽  
pp. 816-820
Author(s):  
SAHIBZADA SAEED JAN ◽  
AMIN JAN ◽  
JAN.I.ALAM ◽  
TAJ MUHAMMAD KHAN

BACKGROUND: Diabetes mellitus is a well recognized risk factor for acute stroke, resulting in agreater ischemic to hemorrhagic stroke ratio in the people with diabetes compared with the generalpopulation. Diabetes also doubles the risk of stroke recurrence and has a poor outcome (or having poorprognosis for survival) as compared to non-diabetic patients, warranting strong and comprehensivepreventive efforts, The aim of this study was to evaluate the High Density Lipoprotein-Cholesterol(HDL-C) level in the adult diabetic and non-diabetic stroke patients coming to Medical Unit of SaiduTeaching Hospital, Swat.MATERIAL AND METHODOLOGY: This was a cross-sectional study, comprised of 100 subjects,50 were diabetic and 50 were non -diabetic stroke patients of ages between 40 to 90 years. The studysubjects underwent a detailed history and examination. Individuals with a history of medications knownto affects body composition, patients on anti-coagulants and having a history of blood dyscrasias likeleukemia’s, thalasemia, polycythemia, endocrinopathies and patients having clotting disorders, extraduraland intradural hemorrhage as a cause of stroke were excluded from the study. Fasting as well as randomblood sample were drawn from the participants for biochemical assays. The serum HDL-C level, bloodsugar (random and fasting), blood pressure (systolic and diastolic) of Diabetic stroke subjects werecompared with Non-diabetic stroke subjects.RESULTS: The HDL-C level was significantly low in our study in diabetic as compared to nondiabetic stroke subjects.CONCLUSION: The low HDL-C level along with poor metabolic control is an important risk factorfor chronic complications of diabetes mellitus like microvascular and macrovascular disease likeunstable angina, myocardial infarction and stroke. Therefore there is intense need of early screening andinterventions, to prevent macrovascular complications especially stroke in high risk diabetic patients.KEY WORDS: Diabetes mellitus, High-density Lipoprotein-Cholesterol (HDL-C), Blood pressure,Stroke.


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