Remnant-like particle cholesterol and serum amyloid A–low-density lipoprotein levels in obese subjects with metabolic syndrome

2011 ◽  
Vol 5 (5) ◽  
pp. 395-400 ◽  
Author(s):  
Kazuhiko Kotani ◽  
Noriko Asahara-Satoh ◽  
Yasuhisa Kato ◽  
Rika Araki ◽  
Akihiro Himeno ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Serum Amyloid A ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Amyloid ◽  
Low Density ◽  
Amyloid A ◽  
Obese Subjects

scholarly journals Serum Amyloid a Low-Density Lipoprotein Levels and Smoking Status in Obese Japanese Patients

2011 ◽  
Vol 39 (5) ◽  
pp. 1917-1922 ◽  
Author(s):  
K Kotani ◽  
N Satoh-Asahara ◽  
Y Kato ◽  
R Araki ◽  
A Himeno ◽  
...  
Keyword(s):  
Serum Amyloid A ◽  
Smoking Status ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Japanese Patients ◽  
Serum Amyloid ◽  
Low Density ◽  
Amyloid A

Influence of atorvastatin on serum amyloid A-low density lipoprotein complex in hypercholesterolemic patients

2012 ◽  
Vol 64 (1) ◽  
pp. 212-216 ◽  
Author(s):  
Kotani Kazuhiko ◽  
Yamada Toshiyuki ◽  
Miyamoto Michiaki ◽  
Ishibashi Shun ◽  
Taniguchi Nobuyuki ◽  
...  
Keyword(s):  
Serum Amyloid A ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Amyloid ◽  
Low Density ◽  
Amyloid A ◽  
Lipoprotein Complex

Effect of statins on atherogenic serum amyloid A and α1-antitrypsin low-density lipoprotein complexes

2016 ◽  
Vol 225 ◽  
pp. 332-336 ◽  
Author(s):  
Yusuke Miyazaki ◽  
Yasufumi Katanasaka ◽  
Yoichi Sunagawa ◽  
Sae Hirano-Sunagawa ◽  
Masafumi Funamoto ◽  
...  
Keyword(s):  
Serum Amyloid A ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Amyloid ◽  
Low Density ◽  
Amyloid A

Correlation Between Serum Amyloid A-low Density Lipoprotein And Genotoxicity In Smokers

2018 ◽  
Vol 28 (2) ◽  
pp. 89-92
Author(s):  
Aneela Jamil ◽  
◽  
Amir Rashid ◽  
Abdul Khaliq Naveed ◽  
Asifa Majeed Majeed
Keyword(s):  
Serum Amyloid A ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Amyloid ◽  
Low Density ◽  
Amyloid A

scholarly journals Serum concentrations and expressions of serum amyloid A and leptin in adipose tissue are interrelated: the Genobin Study

2008 ◽  
Vol 158 (3) ◽  
pp. 333-341 ◽  
Author(s):  
T Lappalainen ◽  
M Kolehmainen ◽  
U Schwab ◽  
L Pulkkinen ◽  
D E Laaksonen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Metabolic Syndrome ◽  
Adipose Tissue ◽  
Weight Reduction ◽  
Serum Amyloid A ◽  
Normal Weight ◽  
Serum Amyloid ◽  
Serum Concentrations ◽  
Amyloid A ◽  
Obese Subjects

ObjectiveSerum amyloid A (SAA) is a novel link between increased adipose tissue mass and low-grade inflammation in obesity. Little is known about the factors regulating its serum concentration and mRNA levels. We investigated the association between SAA and leptin in obese and normal weight subjects and analyzed the effect of weight reduction on serum SAA concentration and gene expression in adipose tissue of the obese subjects.MethodsSeventy-five obese subjects (60±7 years, body mass index (BMI) 32.9±2.8 kg/m2, mean±s.d.) with impaired fasting plasma glucose or impaired glucose tolerance and other features of metabolic syndrome, and 11 normal weight control subjects (48±9 years, BMI 23.7±1.9 kg/m2) were studied at the baseline. Twenty-eight obese subjects underwent a 12-week intensive weight reduction program followed by 5 months of weight maintenance. Blood samples and abdominal s.c. adipose tissue biopsies were taken at the baseline and after the follow-up. Gene expression was studied using real-time quantitative PCR.ResultsThe gene expressions in women and serum concentrations of leptin and SAA were interrelated independently of body fat mass in the obese subjects (r=0.54, P=0.001; r=0.24, P=0.039 respectively). In multiple linear regression analyses, leptin mRNA explained 38% of the variance in SAA mRNA (P=0.002) in the obese women. Weight loss of at least 5% increased SAA mRNA expression by 48 and 36% in men and women, but serum SAA concentrations did not change.ConclusionsThe association between SAA and leptin suggests an interaction between these two adipokines, which may have implications in inflammatory processes related to obesity and the metabolic syndrome.

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