A pilot study of hippocampal N-acetyl-aspartate in youth with treatment resistant major depression

2017 ◽  
Vol 207 ◽  
pp. 110-113 ◽  
Author(s):  
Danielle Lefebvre ◽  
Lisa Marie Langevin ◽  
Natalia Jaworska ◽  
Ashley D. Harris ◽  
R. Marc Lebel ◽  
...  
Keyword(s):  
Pilot Study ◽  
Major Depression ◽  
Treatment Resistant

P.303 Augmenting strategies for treatment-resistant major depression using atypical antipsychotics

2021 ◽  
Vol 44 ◽  
pp. S40-S41
Author(s):  
I.A. Alexandru ◽  
I.E. Ghenoiu ◽  
R.E. Manolache ◽  
R.A. Lecu ◽  
M.I. Gionea
Keyword(s):  
Major Depression ◽  
Atypical Antipsychotics ◽  
Treatment Resistant

Treatment of Aggressive Behavior in Dementia With the Anticonvulsant Topiramate: A Retrospective Pilot Study

2003 ◽  
Vol 15 (3) ◽  
pp. 307-309 ◽  
Author(s):  
Benny Fhager ◽  
Inga-Maj Meiri ◽  
Magnus Sjögren ◽  
Åke Edman
Keyword(s):  
Quality Of Life ◽  
Pilot Study ◽  
Side Effects ◽  
Aggressive Behavior ◽  
Extrapyramidal Side Effects ◽  
Treatment Resistant ◽  
Careful Treatment ◽  
And Training ◽  
Low Dosage

Aggressive behavior in dementia often has a severe impact on the quality of life of the patient and the caregivers, and is therefore important to handle. The strategy of treatment should be broad. Nonpharmacological interventions, including environmental adjustments and supporting and training the caregivers, should always be considered. Pharmacological treatment of aggressive behavior in patients with dementia often includes the use of neuroleptics. The atypical compounds clozapine, risperidone, and olanzapine have been shown to have an effect on aggressive behavior at low dosage with limited extrapyramidal side effects. The anticonvulsants carbamazepine and sodium valproate are further alternatives. In treatment-resistant cases, buspirone or lithium may be tried, although the effect of these substances on aggressive behavior in dementia has not been well established. In the end, however, a considerable degree of aggressive behavior sometimes remains after careful treatment trials, particularly in patients with severe aggressive behavior. In addition, treatment is sometimes limited by side effects.

A Treatment-Resistant Default Mode Subnetwork in Major Depression

2013 ◽  
Vol 74 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Baojuan Li ◽  
Li Liu ◽  
Karl J. Friston ◽  
Hui Shen ◽  
Lubin Wang ◽  
...  
Keyword(s):  
Major Depression ◽  
Treatment Resistant ◽  
Default Mode
Sign in / Sign up

Export Citation Format

Share Document