The permeability of the blood in the artificial cancellous are affected by certain morphological aspects that include pore diameter, pore size, porosity and the bone surface area. In this study, computational fluid dynamics method is used to study the fluid flow through the cancellous structure. Result of the present work show that geometries with the same porosity and overall volume can have different permeability due to the differences in bone surface area. The hexahedron geometry has the highest permeability under stimulated blood flow conditions, where the cylindrical geometry has the lowest. Linear relationship is found between permeability and the two physical properties, bone surface area and the pore size.