O4-06-04: Intraneuronal Abeta42 aggregates seed amyloid plaques and cause neuronal loss in transgenic mice with five familial Alzheimer's disease mutations

2006 ◽  
Vol 2 ◽  
pp. S88-S88
Author(s):  
Robert Vassar ◽  
Holly Oakley ◽  
Sreemathi Logan ◽  
Erika Maus ◽  
Pei Shao ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Transgenic Mice ◽  
Neuronal Loss ◽  
Amyloid Plaques ◽  
Familial Alzheimer’S Disease ◽  
Disease Mutations ◽  
Familial Alzheimer's Disease

scholarly journals Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

2010 ◽  
Vol 176 (1) ◽  
pp. 353-368 ◽  
Author(s):  
Miguel A. Gama Sosa ◽  
Rita De Gasperi ◽  
Anne B. Rocher ◽  
Athena Ching-Jung Wang ◽  
William G.M. Janssen ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Transgenic Mice ◽  
Vascular Pathology ◽  
Presenilin 1 ◽  
Familial Alzheimer’S Disease ◽  
Age Related ◽  
Disease Mutations ◽  
Familial Alzheimer's Disease

scholarly journals Cerebellar Amyloid-β Plaques: Disturbed Cortical Circuitry in AβPP/PS1 Transgenic Mice as a Model of Familial Alzheimer's Disease

2012 ◽  
Vol 31 (2) ◽  
pp. 285-300 ◽  
Author(s):  
Selene Lomoio ◽  
Irene López-González ◽  
Ester Aso ◽  
Margarita Carmona ◽  
Benjamín Torrejón-Escribano ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Transgenic Mice ◽  
Amyloid Β ◽  
Familial Alzheimer’S Disease ◽  
Cortical Circuitry ◽  
Familial Alzheimer's Disease

scholarly journals Effects of Risk Genes on BOLD Activation in Presymptomatic Carriers of Familial Alzheimer's Disease Mutations during a Novelty Encoding Task

2010 ◽  
Vol 21 (4) ◽  
pp. 877-883 ◽  
Author(s):  
J. M. Ringman ◽  
L. D. Medina ◽  
M. Braskie ◽  
Y. Rodriguez-Agudelo ◽  
D. H. Geschwind ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Familial Alzheimer’S Disease ◽  
Risk Genes ◽  
Disease Mutations ◽  
Familial Alzheimer's Disease

P1-412: Isoprenoids phenocopy familial Alzheimer's disease mutations and regulate gamma-secretase

2008 ◽  
Vol 4 ◽  
pp. T340-T340
Author(s):  
Kumar Sambamurti ◽  
Annamalai Prakasam ◽  
Anusuya Devi Jayachandran ◽  
Chitra Venugopal ◽  
Jagannatha K.S. Rao ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Gamma Secretase ◽  
Familial Alzheimer’S Disease ◽  
Disease Mutations ◽  
Familial Alzheimer's Disease
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