Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

Age Related ◽

Disease Mutations ◽

Enhanced Synaptic Potentiation in Transgenic Mice Expressing presenilin 1 Familial Alzheimer's Disease Mutation Is Normalized with a Benzodiazepine

Neurobiology of Disease ◽

10.1006/nbdi.1999.0271 ◽

2000 ◽

Vol 7 (1) ◽

pp. 54-63 ◽

Cited By ~ 42

Author(s):

Shahid H. Zaman ◽

Angèle Parent ◽

Aaron Laskey ◽

Michael K. Lee ◽

David R. Borchelt ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mice ◽

Presenilin 1 ◽

Synaptic Potentiation ◽

Disease Mutation ◽

Impairments in Fast Axonal Transport and Motor Neuron Deficits in Transgenic Mice Expressing Familial Alzheimer's Disease-Linked Mutant Presenilin 1

Journal of Neuroscience ◽

10.1523/jneurosci.4272-06.2007 ◽

2007 ◽

Vol 27 (26) ◽

pp. 7011-7020 ◽

Cited By ~ 92

Author(s):

O. Lazarov ◽

G. A. Morfini ◽

G. Pigino ◽

A. Gadadhar ◽

X. Chen ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mice ◽

Motor Neuron ◽

Axonal Transport ◽

Presenilin 1 ◽

Fast Axonal Transport ◽

Familial Alzheimer’s disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts

BIOPHYSICS ◽

10.1134/s0006350910050131 ◽

2010 ◽

Vol 55 (5) ◽

pp. 760-764

Author(s):

A. L. Schwarzman ◽

S. V. Sarantseva ◽

O. L. Runova ◽

E. I. Talalaeva ◽

M. P. Vitek

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cell Adhesion ◽

Presenilin 1 ◽

Disease Mutations ◽

Familial Alzheimer's Disease ◽

Cell Cell

Familial Alzheimer's Disease Mutations in Presenilin-1 and Store-Operated Calcium Entry

Biophysical Journal ◽

10.1016/j.bpj.2010.12.3222 ◽

2011 ◽

Vol 100 (3) ◽

pp. 554a

Author(s):

Maria Ryazantseva ◽

Lyubov Glushankova ◽

Ilya Pozdnyakov ◽

Ilya Bezprozvanny ◽

Elena Kaznacheyeva

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Calcium Entry ◽

Presenilin 1 ◽

Disease Mutations ◽

Store Operated Calcium Entry ◽

95 Synthesis and metabolism of presenilin 1 with mutations linked to familial Alzheimer's disease in transgenic mice

Neurobiology of Aging ◽

10.1016/s0197-4580(96)80097-2 ◽

1996 ◽

Vol 17 (4) ◽

pp. S24

Author(s):

D. Borchelt ◽

M. Lee ◽

G. Thinakaran ◽

P.C. Wong ◽

H.H.H.H. Slunt ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mice ◽

Presenilin 1 ◽

O4-06-04: Intraneuronal Abeta42 aggregates seed amyloid plaques and cause neuronal loss in transgenic mice with five familial Alzheimer's disease mutations

Alzheimer s & Dementia ◽

10.1016/j.jalz.2006.05.339 ◽

2006 ◽

Vol 2 ◽

pp. S88-S88

Author(s):

Robert Vassar ◽

Holly Oakley ◽

Sreemathi Logan ◽

Erika Maus ◽

Pei Shao ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mice ◽

Neuronal Loss ◽

Amyloid Plaques ◽

Disease Mutations ◽

O2-03-02: Stepwise autoproteolysis of presenilin 1 is affected by familial Alzheimer's disease mutations

Alzheimer s & Dementia ◽

10.1016/j.jalz.2010.05.315 ◽

2010 ◽

Vol 6 ◽

pp. S101-S101

Author(s):

Christian Haass ◽

Akio Fukumori ◽

Harald Steiner

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Presenilin 1 ◽

Disease Mutations ◽

O2-04-06: The role of presenilin 1 familial Alzheimer's disease mutations for gamma-secretase activity and changed structural conformation

Alzheimer s & Dementia ◽

10.1016/j.jalz.2012.05.645 ◽

2012 ◽

Vol 8 (4S_Part_7) ◽

pp. P242-P242

Author(s):

Patricia Lara Vasquez ◽

Johanna Wanngren ◽

Silvia Maioli ◽

Lars Tjernberg ◽

Bengt Winblad ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Presenilin 1 ◽

Gamma Secretase ◽

Structural Conformation ◽

Disease Mutations ◽

Secretase Activity ◽

Staurosporine-Induced Activation of Caspase-3 Is Potentiated by Presenilin 1 Familial Alzheimer's Disease Mutations in Human Neuroglioma Cells

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1999.0732278.x ◽

2002 ◽

Vol 73 (6) ◽

pp. 2278-2285 ◽

Cited By ~ 33

Author(s):

Dora M. Kovacs ◽

Ronald Mancini ◽

John Henderson ◽

Sang J. Na ◽

Stephen D. Schmidt ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Caspase 3 ◽

Presenilin 1 ◽

Disease Mutations ◽

Familial Alzheimer's Disease Mutations in Presenilin 1 Do Not Alter Levels of the Secreted Amyloid Protein Precursor Generated by -Secretase Cleavage

Current Alzheimer Research ◽

10.2174/1567209197155492050 ◽

2009 ◽

Vol 999 (999) ◽

pp. 1-6

Author(s):

Rudolph E. Tanzi

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Presenilin 1 ◽

Amyloid Protein ◽

Protein Precursor ◽

Amyloid Protein Precursor ◽

Disease Mutations ◽