O1-01-05: Long-term use of angiotensin receptor blockers and risk of Alzheimer's disease in a cohort of patients with hypertension

2010 ◽  
Vol 6 ◽  
pp. S69-S69
Author(s):  
Rachel A. Whitmer ◽  
Peter Zandi ◽  
Charles P. Quesenberry ◽  
Jufen Zhou ◽  
Benjamin Wolozin
Drugs & Aging ◽  
2013 ◽  
Vol 30 (6) ◽  
pp. 367-372 ◽  
Author(s):  
Hitomi Kurinami ◽  
Munehisa Shimamura ◽  
Naoyuki Sato ◽  
Hironori Nakagami ◽  
Ryuichi Morishita

2015 ◽  
Vol 156 (5) ◽  
pp. 179-185 ◽  
Author(s):  
Gergely Fehér ◽  
Gabriella Pusch

The treatment of migraine depends on the frequency, severity and concomitant diseases. There are several specific drugs developed for migraine prevention in addition to the additive antimigraine effects of some other non-specific drugs. The aim of this literature-based review is to summarize the possible antimigraine properties of different antihypertensive agents (beta-blockers, calcium channel blockers, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, etc.) focusing on the possible side effects (avoidance of beta blockers in the absence of heart disease, possible antiparkinson effect of calcium channel blockers, additive effect of drugs modifying the renin-angiotensin system activity, etc.). Current evidence supports the use of angiotensin converting enzyme inhibitors (mainly lisinopril) and angiotensin receptor blockers (mainly candesartan) for long-term migraine prevention and blood pressure control. Long-term beta-blocker treatment should be avoided in the absence of ischemic heart disease due to possible unfavourable cardiovascular effects. Orv. Hetil., 2015, 156(5), 179–185.


2013 ◽  
Vol 10 (2) ◽  
pp. 13-18
Author(s):  
T E Morozova

This paper presents an overview of the literature on the treatment of arterial hypertension drugs that block the renin-angiotensin-aldosterone system (RAAS) – angiotensin receptor blockers ΙΙ (ARB), whose action is based on inhibition of the RAAS at the AII receptor. ARB candesartan (atakand), along with a strong long-term antihypertensive effect has organoprotective (causes regression of LVH has nephroprotection) antidiabetogennym effect, prevents the development of stroke. Clinical experience suggests candesartan, high efficiency and a good range of security among different categories of hypertensive patients with concomitant pathology, chronic heart failure, diabetes, obesity.


PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e50893 ◽  
Author(s):  
Laurent Azoulay ◽  
Themistocles L. Assimes ◽  
Hui Yin ◽  
Dorothee B. Bartels ◽  
Ernesto L. Schiffrin ◽  
...  

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