[P1-601]: DESIGN OF CONTROLS IN TRIALS OF COMPUTERISED COGNITIVE TRAINING IS INEFFECTUAL: A META-ANALYSIS IN HEALTHY OLDER ADULTS

2017 ◽  
Vol 13 (7S_Part_10) ◽  
pp. P526-P526 ◽  
Author(s):  
Harry Hallock ◽  
Anna Radowiecka ◽  
Kathryn M. Broadhouse ◽  
Isabella Hoi Kei Leung ◽  
Michael Valenzuela ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Training ◽  
Meta Analysis ◽  
Healthy Older Adults

scholarly journals Functional Brain Changes Associated with Cognitive Training in Healthy Older Adults: A Preliminary ALE Meta-Analysis

2018 ◽  
Author(s):  
Bryant M. Duda ◽  
Lawrence Sweet
Keyword(s):  
Older Adults ◽  
Cognitive Training ◽  
Neural Activity ◽  
Healthy Aging ◽  
Posterior Parietal Cortex ◽  
Right Hemisphere ◽  
Meta Analysis ◽  
Middle Frontal Gyrus ◽  
Precentral Gyrus ◽  
Healthy Older Adults

Accumulating evidence suggests that cognitive training (CT) programs may provide healthy older adults (OAs) with cognitive benefits that are accompanied by alterations in neural activity. The current review offers the first quantitative synthesis of the available literature on the neural effects of CT in healthy aging. It was hypothesized that OAs would evidence increased and decreased neural activations across various challenging CTs, and that these effects would be observed as significantly altered clusters within regions of the frontoparietal network (FPN). Online databases and reference lists were searched to identify peer-reviewed publications that reported assessment of neural changes associated with CT programs in healthy OAs. Among the 2097 candidate studies identified, 14 studies with a total of 238 participants met inclusionary criteria. GingerALE software was used to quantify neural effects in a whole-brain analysis. The activation likelihood estimation technique revealed significant increases in activation following CT in the left hemisphere middle frontal gyrus, precentral gyrus, and posterior parietal cortex, extending to the superior occipital gyrus. Two clusters of diminished neural activity following CT were identified within the right hemisphere middle frontal gyrus and supramarginal gyrus, extending to the superior temporal gyrus. These results provide preliminary evidence of common neural effects of different CT interventions within regions of the FPN. Findings may inform future investigations of neuroplasticity across the lifespan, including clinical applications of CT, such as assessing treatment outcomes.

scholarly journals Repetition Priming in Individuals with Amnestic Mild Cognitive Impairment and Alzheimer’s Dementia: a Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Liselotte De Wit ◽  
Vitoria Piai ◽  
Pilar Thangwaritorn ◽  
Brynn Johnson ◽  
Deirdre O’Shea ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Repetition Priming ◽  
Meta Analysis ◽  
Healthy Older Adults ◽  
Amnestic Mci ◽  
Standard Mean Difference ◽  
Priming Paradigm

AbstractThe literature on repetition priming in Alzheimer’s disease (AD) is inconsistent, with some findings supporting spared priming while others do not. Several factors may explain these inconsistencies, including AD severity (e.g., dementia vs. Mild Cognitive Impairment; MCI) and priming paradigm-related characteristics. This systematic review and meta-analysis provides a quantitative summary of repetition priming in AD. We examined the between-group standard mean difference comparing repetition priming in AD dementia or amnestic MCI (aMCI; presumably due to AD) to controls. Thirty-two studies were selected, including 590 individuals with AD dementia, 267 individuals with amnestic MCI, and 703 controls. Our results indicated that both individuals with aMCI and AD dementia perform worse on repetition priming tasks than cognitively older adults. Paradigm-related moderators suggested that the effect size between studies comparing the combined aMCI or AD dementia group to cognitively healthy older adults was the highest for paradigms that required participants to produce, rather than identify, primes during the test phase. Our results further suggested that priming in AD is impaired for both conceptual and perceptual priming tasks. Lastly, while our results suggested that priming in AD is impaired for priming tasks that require deep processing, we were unable to draw firm conclusions about whether priming is less impaired in aMCI or AD dementia for paradigms that require shallow processing.

scholarly journals EFFECT ASSESSMENT OF A COGNITIVE TRAINING PLATFORM IN HEALTHY OLDER ADULTS

2017 ◽  
Vol 5 ◽  
pp. 1032-1035
Author(s):  
Antonia Yaneva ◽  
Nonka Mateva
Keyword(s):  
Older Adults ◽  
Cognitive Training ◽  
Cognitive Functions ◽  
Cognitive Status ◽  
Post Intervention ◽  
Healthy Older Adults ◽  
Computerized Cognitive Training ◽  
Negative Results ◽  
Healthy Elderly ◽  
Traditional Programs

Cognitive interventions, especially cognitive training, may improve cognitive functions in healthy older adults. Computerized cognitive training platforms offer several advantages over traditional programs for cognitive training and stimulation. The focus of this article is the methodology of the studies that apply a particular online training program. We investigate the effectiveness of several studies for cognitive training in healthy elderly people and evaluate reported outcomes and potential bias and what factors determine, influence or contribute to the positive or negative results. The post-intervention scores demonstrate that computerized cognitive training may enhance some cognitive functions and the overall cognitive status but there is need for additional research to prove its effectiveness.

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