PHASE II CLINICAL TRIAL WITH AN AMPA-POSITIVE ALLOSTERIC MODULATOR (S 47445): BASELINE DEMOGRAPHIC AND CLINICAL CHARACTERISTICS OF PATIENTS SUFFERING FROM ALZHEIMER’S DISEASE AT MILD TO MODERATE STAGES WITH DEPRESSIVE SYMPTOMS

2017 ◽  
Vol 13 (7) ◽  
pp. P575 ◽  
Author(s):  
Jeffrey L. Cummings ◽  
Katy Bernard ◽  
Sylvie Bretin ◽  
Sylvie Gouttefangeas ◽  
Maria Pueyo
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Depressive Symptoms ◽  
Phase Ii ◽  
Clinical Characteristics ◽  
Phase Ii Clinical Trial ◽  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
Baseline Demographic

P2-027: TARGET ENGAGEMENT IN A PHASE II CLINICAL TRIAL OF AAV2-NGF GENE THERAPY FOR ALZHEIMER'S DISEASE

2006 ◽  
Vol 14 (7S_Part_12) ◽  
pp. P677-P677
Author(s):  
Michael J. Castle ◽  
Fernando Calvo Baltanas ◽  
Imre Kovacs ◽  
Alan H. Nagahara ◽  
Krystof S. Bankiewicz ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Gene Therapy ◽  
Phase Ii ◽  
Phase Ii Clinical Trial ◽  
Target Engagement ◽  
Ngf Gene

Donepezil Improves Gait Performance in Older Adults with Mild Alzheimer's Disease: A Phase II Clinical Trial

2014 ◽  
Vol 43 (1) ◽  
pp. 193-199 ◽  
Author(s):  
Manuel Montero-Odasso ◽  
Susan W. Muir-Hunter ◽  
Afua Oteng-Amoako ◽  
Karen Gopaul ◽  
Anam Islam ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Phase Ii ◽  
Phase Ii Clinical Trial ◽  
Gait Performance

scholarly journals O4-06-05: PF-04447943: A phase II controlled clinical trial of a selective PDE9A inhbitor in Alzheimer's disease

2011 ◽  
Vol 7 ◽  
pp. S695-S695 ◽  
Author(s):  
Elias Schwam ◽  
Rebecca Evans ◽  
Timothy Nicholas ◽  
Robert Chew ◽  
Wendy Davidson ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Phase Ii ◽  
Controlled Clinical Trial

P3-037: CLINICAL TRIAL DESIGN FOR A PHASE II, RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF AMX0035 IN ALZHEIMER'S DISEASE

2006 ◽  
Vol 14 (7S_Part_20) ◽  
pp. P1078-P1079
Author(s):  
Kent L. Leslie ◽  
Joshua Cohen ◽  
Justin Klee ◽  
Victoria Williams ◽  
Steven E. Arnold
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Phase Ii ◽  
Trial Design ◽  
Controlled Trial ◽  
Clinical Trial Design

A positive allosteric modulator of mGluR5 promotes neuroprotective effects in mouse models of Alzheimer's disease

2019 ◽  
Vol 160 ◽  
pp. 107785 ◽  
Author(s):  
Paula Maria Quaglio Bellozi ◽  
Giovanni Freitas Gomes ◽  
Maria Carolina Machado da Silva ◽  
Isabel Vieira de Assis Lima ◽  
Carla Ribeiro Álvares Batista ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mouse Models ◽  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
Neuroprotective Effects
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